Auriga Announces New Alliance with Degussa to Enhance Product Pipeline Targeting Chronic Gastro-Intestinal Diseases; Technology to Leverage Degussa's Novel EUDRACOL(TM) Technology to Improve Drug Dosing, Efficacy and Reduce Side Effects in GI Tract.NORCROSS, Ga. -- Auriga Laboratories, Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :ARGA ARGA Arkansas Rice Growers Association (North Little Rock, AR) ), a specialty pharmaceutical company dedicated to applying advances in drug delivery to improve and extend the value of medicines for improved patient outcomes and the marketer of the Extendryl(R) family of products, announces the execution of a strategic agreement with Degussa to develop a proprietary formulation targeting serious chronic gastrointestinal diseases utilizing Degussa's proprietary EUDRACOL(TM) technology. Auriga is developing an oral, controlled-release corticosteroid corticosteroid /cor·ti·co·ster·oid/ (-ster´oid) any of the steroids elaborated by the adrenal cortex (excluding the sex hormones) or any synthetic equivalents; divided into two major groups, the glucocorticoids and formulation that targets inflammatory bowel disease inflammatory bowel disease n. Abbr. IBD Any of several incurable and debilitating diseases of the gastrointestinal tract characterized by inflammation and obstruction of parts of the intestine. lesions at different sites within the GI tract. Degussa, the world's largest specialty chemical company, will provide the proprietary drug delivery technology and formulation concentrating the therapeutic benefits of the selected corticosteroid specifically where it is needed in the GI tract, providing dosing and efficacy, and reducing side effects Side effects Effects of a proposed project on other parts of the firm. . "We're very excited to announce this development alliance with Degussa, which provides Auriga with an opportunity to design improved drug delivery treatments for inflammatory diseases of the bowel by leveraging the unique features of the EUDRACOL(TM) technology platform," said Philip Pesin, Chief Executive Officer of Auriga. "Auriga has always held a fundamental belief that corticosteroids Corticosteroids Definition Corticosteroids are group of natural and synthetic analogues of the hormones secreted by the hypothalamic-anterior pituitary-adrenocortical (HPA) axis, more commonly referred to as the pituitary gland. represent a major untapped therapeutic resource for the treatment of Crohn's disease
The treatment of Crohn's disease is sequential: to treat acute disease, and then to maintain remission. Treatment initially involves the use of medications to treat any infection and to reduce inflammation. . We are very pleased to see our belief has now been justified with the recent announcement by the American Academy of Gastroenterology, recommending a corticosteroid as first-line therapy for mild to moderate Crohn's. This recommendation is a significant first step in opening up what we see as a new and exciting era in the treatment of this debilitating de·bil·i·tat·ing adj. Causing a loss of strength or energy. Debilitating Weakening, or reducing the strength of. Mentioned in: Stress Reduction disease." Drug delivery to specific disease sites within the GI tract is essential for the creation of improved pharmacological treatments with greater efficacy and reduced side effects for the patient suffering from Inflammatory Bowel Diseases (IBD IBD abbr. inflammatory bowel disease Inflammatory bowel disease (IBD) Disease in which the lining of the intestine becomes inflamed. Mentioned in: Amebiasis IBD 1. ). By joining forces with Degussa now to develop this novel formulation with targeted delivery, and in combination with Auriga's existing development pipeline, Auriga establishes itself as a valued development partner in the specialty pharmaceutical marketplace. Under the terms of the development agreement, Degussa is responsible for development of the prototype formulations. Auriga Laboratories is responsible for formulation scale-up, manufacture, clinical, regulatory submission/approval, and product launch and marketing. EUDRACOL(TM) is a proprietary multi-layer colonic drug delivery system that is designed to provide drug protection in the upper gastrointestinal tract gastrointestinal tract n. The part of the digestive system consisting of the stomach, small intestine, and large intestine. Gastrointestinal tract and controlled drug release in the ileum ileum: see intestine. ileum Final and longest segment of the small intestine. It is the site of absorption of vitamin B12 (see vitamin B complex) and reabsorption of about 90% of conjugated bile salts. and colon. About Degussa Degussa is the global market leader in specialty chemicals. Its business is creating essentials-innovative products and system solutions that make indispensable contributions to the customers' success. Degussa has developed cutting-edge oral drug delivery technologies based on EUDRAGIT(R) polymers. A broad range of EUDRAGIT(R) products are widely used throughout the pharmaceutical industry as coatings for modified release dosage forms. For more information, visit www.degussa.com. About Auriga Auriga is a specialty pharmaceutical company with sales, marketing, and development capabilities. Auriga has an exclusive license the Extendryl(R) family of products and promotes the products through its dedicated sales force. The Extendryl(R) line is indicated for treatment and relief of cough, cold and allergy symptoms. These products offer different combinations of antihistamines Antihistamines Definition Antihistamines are drugs that block the action of histamine (a compound released in allergic inflammatory reactions) at the H1 , expectorants Expectorants Definition Expectorants are drugs that loosen and clear mucus and phlegm from the respiratory tract. Purpose The drug described here, guaifenesin, is a common ingredient in cough medicines. , decongestants Decongestants Definition Decongestants are medicines used to relieve nasal congestion (stuffy nose). Purpose A congested or stuffy nose is a common symptom of colds and allergies. , anticholinergics, and anti-tussive that are designed to provide symptomatic relief for several patient types in the acute respiratory disease area. Auriga plans to become a fully integrated pharmaceutical company by acquiring its own manufacturing and development capabilities. Moving forward, the Company will complement its internal development efforts via acquisition and/or in-license additional products and technologies to further grow revenues. For more information, please visit: www.aurigalabs.com. For investor-specific information and resources, visit http://www.trilogy-capital.com/tcp/auriga/. To read or download Auriga's Investor Fact Sheet, please visit http://www.trilogy-capital.com/tcp/auriga/factsheet.html. To view current stock quotes and news, visit http://www.trilogy-capital.com/tcp/auriga/quote.html. Forward-Looking Statements The information contained herein includes forward-looking statements. These statements relate to future events or to our future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance, or achievements to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond our control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects our current views with respect to future events and is subject to these and other risks, uncertainties and assumptions relating to our operations, results of operations, growth strategy and liquidity. We assume no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. The safe harbor for forward-looking statements contained in the Securities Litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute. When a person begins a civil lawsuit, the person enters into a process called litigation. Reform Act of 1995 protects companies from liability for their forward-looking statements if they comply with the requirements of the Act. |
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