Atypical Improves Cognition in First Episode Psychosis.
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See Windows XP. , B.C. -- The atypical antipsychotic The atypical anti-psychotics (also known as second generation anti-psychotics) are a class of prescription medications used to treat psychiatric conditions. Some atypical anti-psychotics are FDA approved for use in the treatment of schizophrenia. agent quetiapine proved beneficial in measures of cognitive function cognitive function Neurology Any mental process that involves symbolic operations–eg, perception, memory, creation of imagery, and thinking; CFs encompasses awareness and capacity for judgment in young patients experiencing a first episode of psychosis, Dr. L. Kopala reported at a meeting of the International Congress on Schizophrenia Research.
"Cognitive dysfunction is the most important predictor of future social and occupational functioning in patients with psychotic disorders," said Dr. Kopala of the department of psychiatry, Dalhousie University Dalhousie University (dălhou`zē), at Halifax, N.S., Canada; nonsectarian; coeducational; founded 1818 by the 9th earl of Dalhousie. Except for a few years between 1838 and 1845, Dalhousie did not function as a university until 1863. , Halifax, N.S. It traditionally has been considered a core feature of the illness and is unlikely to be amenable to treatment. A recent review suggested that cognitive function may worsen following treatment with the standard antipsychotic drugs Antipsychotic Drugs Definition
Antipsychotic drugs are a class of medicines used to treat psychosis and other mental and emotional conditions.
Purpose (Am. J. Psychiatry 158:176-84, 2001).
In an open-label study that included 30 patients ranging in age from 17 to 39, evaluations of abstraction, fluency, attention, memory, and sensory/motor function were performed at baseline, 3 months, 6 months, and 1 year. "Better performance was observed over time for all of the neuropsychological tests examined," Dr. Kopala reported. "Predictably, the timed motor tasks did not change over time," he said.
Verbal fluency rose from an average total score of 33 at baseline to 39 after 1 year of treatment. Statistically significant improvements were seen on measures of executive function and attention, reported Dr. Kopala, also of the Nova Scotia Nova Scotia (nō`və skō`shə) [Lat.,=new Scotland], province (2001 pop. 908,007), 21,425 sq mi (55,491 sq km), E Canada. Geography
Early Psychosis Program in Dartmouth.
Funding for this study was provided by AstraZeneca Pharmaceuticals.