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Asuragen's microRNA Expression Profiling Service Offers Sanger miRBase 8.0 Plus New Proprietary Content; Enhanced Service Offering Will Expand the Number of microRNAs That Can Be Globally Analyzed for Differential Gene Expression.


AUSTIN, Texas -- Asuragen announces the launch of the next generation of microarray content to be offered through its microRNA Expression Profiling Microarray technology is often used for gene expression profiling. It makes use of the sequence resources created by the genome sequencing projects and other sequencing efforts to answer the question,  Service.

The latest generation of microarrays, manufactured using GE Healthcare's CodeLink(TM) technology, includes microRNA probes corresponding to known human, mouse, and rat microRNAs. In addition to content available through the Sanger miRBase 8.0 database, the array also contains 152 novel microRNAs with confirmed expression in human tissues. These latter sequences are exclusive to Asuragen's microRNA Expression Profiling Service offering and are not available through any other service provider.

"In the era of rapid microRNA discoveries, Asuragen distinguishes its services from those of other providers by offering cutting-edge content, fast turn-around time, and microRNA-specific bioinformatics. The introduction of this next generation content demonstrates Asuragen's commitment to delivering the best quality and most complete data possible," said Scott Hunicke-Smith, Vice President and General Manager of Asuragen Services.

This enhanced service Enhanced service is service offered over commercial carrier transmission facilities used in interstate communications, that employs computer processing applications that act on the format, content, code, protocol, or similar aspects of the subscriber's transmitted information;  offering greatly expands the number of microRNAs that can be globally analyzed for the discovery and analysis of differentially expressed genes in a range of biological systems. In addition to the microRNA Expression Profiling Service, Asuragen also offers Custom Isolation, Gene (mRNA) Expression Profiling, and Bioinformatics Services to support and accelerate molecular biological research.

About microRNAs

MicroRNAs are naturally occurring small RNAs that act to regulate mRNA expression and have the potential to be the basis for a new class of diagnostics and therapeutics. There are approximately 450 microRNAs identified in humans, with the total predicted to eventually reach 1,000 or more. MicroRNAs are believed to regulate at least one-third of the human genes and are likely to play significant roles in the manifestation of many disease states, including metabolic and infectious diseases and cancer.

About Asuragen, Inc.

Asuragen, Inc. is a newly formed company that resulted from the sale, in March, 2006, of the Research Products Division of Ambion, Inc. to Applied Biosystems Group (NYSE NYSE

See: New York Stock Exchange
: ABI Abi (ā`bī) [short for Abijah], in the Bible, King Hezekiah's mother.


(Application Binary Interface) A specification for a specific hardware platform combined with the operating system.
). Asuragen is comprised of two of Ambion's former divisions, Diagnostics and Services, along with the formation of a new Discovery group dedicated to developing new technologies that will become cutting edge clinical products.

Asuragen's current product portfolio consists of Signature(R) Genetic Testing Genetic Testing Definition

A genetic test examines the genetic information contained inside a person's cells, called DNA, to determine if that person has or will develop a certain disease or could pass a disease to his or her offspring.
 and Oncology Testing products, as well as industry leading controls and standards engineered using its patented Armored RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
(R) technology. Asuragen has recently formed a partnership with Digene Corporation (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
: DIGE DIGE Differential In-Gel Electrophoresis
DIGE Direct-Injection Gasoline Engine
) to market and distribute its Signature cystic fibrosis cystic fibrosis (sĭs`tĭk fībrō`sĭs), inherited disorder of the exocrine glands (see gland), affecting children and young people; median survival is 25 years in females and 30 years in males.  screening products.

The vision for Asuragen is to become a fully integrated diagnostic reagent company focused on molecular oncology and early detection of cancer, with emphasis on microRNAs. Comprised of over 100 employees spun out of Ambion, Asuragen is empowered with not only a high level of scientific expertise, but also assay development, business infrastructure and an established cGMP manufacturing facility that allow it to span the spectrum of discovery, production and commercialization.

For more information, visit www.asuragen.com.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Aug 16, 2006
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