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Asterand Offers Researchers Internet Access to RNA to Speed Drug Discovery.


DETROIT -- Asterand (LSE LSE - Language Sensitive Editor :ATD ATD Anthropomorphic Test Dummy
ATD Attention to Detail
ATD Advanced Technology Demonstration
AtD Achieving the Dream
ATD Atmospheric Technology Division (US National Center for Atmospheric Research)
ATD Assistant Technical Director
), the Detroit based biobanking company is offering research scientists simple and easy access to human RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
 samples via the internet.

"This is a valuable new service to help scientists focused on early stage drug discovery," says Dr Victoria Blanc Asterand's Director of Product Development. "The first RNA samples available through Asterand's e-commerce site (http://solutions.asterand.com) include those from common cancers such as breast and colon cancer colon cancer, cancer of any part of the colon (often called the large intestine). Colon cancer is the second most common cancer diagnosed in the United States. . Over time we will be adding thousands of RNA samples from a wide range of diseases."

"The value of RNA analysis is that it is an effective way of differentiating between the diseased state and normal state of tissues. Our provision of this material over the internet expedites the process of identification of novel cellular targets for drug development.

"The high quality RNA coupled with the ease of acquisition is important because the isolation of the RNA is complete, the RNA integrity has been evaluated and approved, and therefore experiments can be planned and executed without delays."

"We are providing scientists with unique and unusual material. Each sample of total RNA is from an individual donor, supplied in 5 [eth]-g aliquots. Asterand standard clinical data are provided with every sample, along with pathology report details, so that the clinical context of the RNA can be understood. Each sample has been quality assured by use of the Agilent Bioanalyzer and confirmed to have an RNA integrity number The RNA integrity number (RIN) is an algorithm for assigning integrity values to RNA measurements.

The integrity of RNA is a major concern for gene expression studies and traditionally has been evaluated using the 28S to 18S rRNA ratio, a method that has been shown to be
 of at least 6, and in tumor tumor: see neoplasm.  samples, no less than 70% tumor cells. This ensures that the materials are suitable for all forms of gene expression analysis - from Northern blots Northern blot

an immunologic technique for the detection of specific messenger RNAs using complementary DNA. Called also Northern transfer.
, to TaqMan to Affymetrix chips.

"Over the last several years we have gained a great deal of experience in processing hundreds of thousands of samples of RNA," says Dr Anja Penger, Director of Biomaterials, and head of the RNA project at Asterand's UK facility in Royston, UK. "Our team has high throughput capacity for measuring and aliquotting samples, bar-coding and distribution. We are very excited to be able to provide the RNA with the efficiency of online sales."

Asterand plc is a UK public company that supports human drug discovery by providing high quality, well characterised human biomaterials and preclinical research services.
COPYRIGHT 2007 Business Wire
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Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Mar 5, 2007
Words:372
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