Aspirin 'cuts stroke risk in patients with peripheral artery disease'.Byline: ANI Washington, May 13 (ANI): Aspirin is likely to reduce the risk of stroke in patients with peripheral artery disease, suggests a new study. Although aspirin is effective in the prevention of cardiovascular events in patients with symptomatic coronary heart disease coronary heart disease: see coronary artery disease. coronary heart disease or ischemic heart disease Progressive reduction of blood supply to the heart muscle due to narrowing or blocking of a coronary artery (see atherosclerosis). and cerebrovascular disease, its effect in patients with peripheral artery disease (PAD) has been uncertain. To determine the effect of aspirin on cardiovascular event rates in patients with PAD, lead researcher Dr Jeffrey S. Berger, of the University of Pennsylvania (body, education) University of Pennsylvania - The home of ENIAC and Machiavelli. http://upenn.edu/. Address: Philadelphia, PA, USA. , Philadelphia conducted a meta-analysis to evaluate available evidence from randomized controlled trials of aspirin therapy, with or without dipyridamole dipyridamole /di·py·rid·a·mole/ (di?pi-rid´ah-mol) a platelet inhibitor and coronary vasodilator used to prevent thromboembolism associated with mechanical heart valves, to treat transient ischemic attacks, and as an adjunct in (an antiplatelet agent), that reported cardiovascular event rates. "Results of this meta-analysis demonstrated that for patients with PAD, aspirin therapy alone or in combination with dipyridamole did not significantly decrease the primary end point of cardiovascular events, results that may reflect limited statistical power," wrote the authors. Even though aspirin use is associated with a statistically nonsignificant non·sig·nif·i·cant adj. 1. Not significant. 2. Having, producing, or being a value obtained from a statistical test that lies within the limits for being of random occurrence. decrease in the risk of a group of combined cardiovascular events but is associated with a significant reduction in the risk of one of these events, nonfatal stroke. "Larger prospective studies of aspirin and other antiplatelet agents are warranted among patients with PAD in order to draw firm conclusions about clinical benefit and risks," the authors added. The study appears in the issue of JAMA JAMA abbr. Journal of the American Medical Association . (ANI) Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency. (ANI) - All Rights Reserved. Provided by Syndigate.info an Albawaba.com company |
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