Aspect Medical Systems Signs Lease Agreement for New Headquarters Facility in Norwood, Mass.

NEWTON, Mass. -- -Provider of Brain Monitoring Technology to Relocate at End of 2006 to Accommodate Growth-

Aspect Medical Systems, Inc. (NASDAQ: ASPM) today announced that it has entered into a lease agreement to relocate its corporate headquarters to One Upland Road in Norwood, Mass. in late 2006. Under the terms of the agreement, the company will occupy 100,000 square feet at the end of 2006 and will expand to 135,000 square feet by 2008. The Norwood facility more than doubles the capacity of Aspect's current facility.

"Aspect has experienced significant growth over the past two years as a result of the increased recognition of the quality and safety benefits that our brain monitoring technology provides for patients and healthcare providers," said Mike Falvey, Aspect's Chief Financial Officer. "We expect this growth to continue in the coming years. The new Upland Road facility provides us with the ability to increase manufacturing capacity so that we can expand our product line and accommodate expected growth while providing a cost effective, high-quality and high-productivity work environment for our employees." Under the terms of the agreement Aspect will lease the facility for ten years with additional rights to extend the lease.

About Aspect Medical Systems, Inc.

Aspect Medical Systems, Inc. (NASDAQ: ASPM) is a global market leader in brain monitoring technology. The Company's BIS technology has been used to assess more than 13.1 million patients and has been the subject of approximately 2,200 published articles and abstracts. BIS technology is installed in approximately 68 percent of America's top-ranked hospitals, as listed in the July 2005 U.S. News and World Report ranking of America's Best Hospitals, and in approximately 41 percent of all domestic operating rooms. In the last twelve months, BIS technology was used in approximately 13% of all U.S. surgical procedures requiring general anesthesia or deep sedation. BIS technology is available in more than 160 countries. Aspect Medical Systems has OEM agreements with seven leading manufacturers of patient monitoring systems. The company is also investigating how other methods of analyzing brain waves may aid in the diagnosis and management of neurological diseases, including depression and Alzheimer's disease. For more information, visit Aspect's web site at http://www.aspectmedical.com.

Safe Harbor Statement

Certain statements in this release are forward-looking and may involve risks and uncertainties, including statements concerning expectations as to the timing of its relocation and expected growth of the Company and use and market acceptance of its products. There are factors that could cause the Company's actual results to vary from its forward-looking statements, including without limitation a failure to complete any modifications to the Company's new facility on a timely basis or at all, a change in, or absence of growth in, market acceptance of the Company's BIS monitoring products, and those factors set forth under the heading " Factors Affecting Future Operating Results" in the Company's Quarterly Report on Form 10-Q for the fiscal quarter ended October 1, 2005 , as filed with the Securities and Exchange Commission. In addition, any forward-looking statements represent the Company's views only as of the date of this press release and should not be relied upon as representing the Company's views as of any subsequent date. While the Company may elect to update forward-looking statements in the future, it specifically disclaims any obligation to do so, even if its expectations change. Therefore, you should not rely on these forward-looking statements as representing the Company's views as of any date subsequent to the date of this press release.

Aspect, Bispectral Index and BIS are registered trademarks of Aspect Medical Systems, Inc. All other trademarks, service marks and company names are the property of their respective owners.