Aspect Medical Systems Features New BIS Education Program, Product Family at American Society of Anesthesiologists Meeting.

BIS technology featured in nearly 100 scientific posters and sessions

NORWOOD, Mass. -- Aspect Medical Systems, Inc. (NASDAQ: ASPM) will present a complete family of BIS[R] products accompanied by a new BIS Education program at the American Society of Anesthesiologists (ASA) Annual Meeting, taking place October 13-17, 2007 in San Francisco. The ASA meeting will also feature nearly 100 scientific studies related to BIS monitoring at the meeting of more than 10,000 anesthesiologists. This research covers a broad spectrum of topics including short and long-term outcome benefits of BIS monitoring and the role of fluctuations in trends of BIS values in assessing patient response during surgery.

"The volume and diversity of BIS-related research presented at the ASA meeting reflect the growing global interest in use of BIS to help clinicians improve the safety and quality of care," said Nassib Chamoun, president and CEO of Aspect. "This interest reinforces the need to provide our customers with more product choices that are best suited to their unique practice requirements, and to provide standardized, scaleable education programs that support their adoption of BIS in clinical practice. The BIS family of monitoring solutions and comprehensive educational programs are designed to address these needs."

Industry-leading brain monitoring products & education programs

The BIS family of products being presented at the meeting includes the BIS VISTA[TM] and BIS VIEW[TM] monitors, and BISx[TM] or modular integration solutions for Datascope, Dixtal, Draeger, GE Healthcare, Mindray, Nihon Kohden, Philips and Spacelabs. To help customers safely and effectively implement use of BIS technologies, Aspect has developed a variety of online and peer-based BIS Education resources.

"We've designed the BIS Education program to allow an ever-increasing number of anesthesia professionals using our monitoring systems to access thorough and consistent training," said Scott Kelley, MD, vice president of medical affairs for Aspect Medical Systems. "The need for formal training regarding proper usage of medical devices in the operating room is a prominent topic at the ASA annual meeting. With more than 40,000 BIS monitors in use, we are committed to providing our customers with a diversity of education resources to enhance the integration of BIS monitoring into their patient care."

BIS Education online resources include:

* Continuing Medical Education (CME) and Continuing Education (CE) accredited activities sponsored by Healthstream[R]

* Interactive clinical overviews of BIS technology utilization

* Simulation technologies developed from BIS case data

* Interactive database of clinical outcomes studies on brain monitoring to support informed medical decisions powered by Dr. Evidence[R]

The BIS Education program also provides customers with resources to facilitate training at the bedside, including a team of clinician educators who are available to provide hands-on training in the operating room or to provide educational lectures.

More information about BIS products and Education can be found during the ASA meeting at the Aspect booth 1804.

Research highlights: anesthetic management and patient outcomes

Research being presented at ASA that was sponsored by Aspect includes two studies that evaluated how rapid changes in BIS values may be useful in assessing patient response to pain during surgery. The first study explored how the brain responds to different forms of surgical stimulation using bilateral BIS monitoring. Study results showed that when stimulation was localized to one side of the body, the opposite brain hemisphere showed a relatively greater response, thereby demonstrating how painful stimulus can lead to specific brain responses. The second study, conducted on pediatric patients, demonstrated that highly variable BIS measurements during surgery were associated with patients reporting greater pain during recovery. This result is consistent with findings from a similar study conducted in adults that were presented at the ASA meeting last year. "Collectively, these studies further suggest that assessing intraoperative BIS variability may be clinically useful in improving pain management and comfort for patients during and after their surgery," said Scott Greenwald, Ph.D., vice president of research at Aspect and co-author of the studies.

A third study provided a prospective, randomized evaluation of 118 patients to explore the relationship between depth of consciousness (as measured by BIS) and changes in inflammatory biomarkers after major orthopedic surgery. BIS-guided anesthesia was compared with standard clinical practice to determine the effects of exposure to inhalational anesthetics on post-operative inflammatory response. Patients in the BIS monitored group showed a reduced C-reactive protein response (a marker of inflammatory response and a strong predictor of future cardiovascular events) compared to standard practice not using BIS. "These findings confirm results from our pilot study conducted last year and suggest that BIS-guided anesthetic titration may help moderate the inflammatory response to the trauma of surgery," said Peter Sebel, MBBS, a professor of anesthesiology at Emory University School of Medicine and investigator in the study.

About BIS Monitoring

Using a sensor placed on the patient's forehead, BIS monitoring translates information from the EEG into a single number that represents each patient's level of consciousness. This number - the BIS value - ranges from 100 (indicating an awake patient) to zero (indicating the absence of brain activity). Using the BIS value to guide administration of anesthetic medication, in conjunction with other vital signs, allows clinicians to make better-informed decisions to achieve optimal anesthesia.

About the Company

Aspect Medical Systems, Inc. (NASDAQ: ASPM) is a global market leader in brain monitoring technology. To date, the Company's Bispectral Index (BIS) technology has been used to assess approximately 20 million patients and has been the subject of more than 2,800 published articles and abstracts. BIS technology is installed in approximately 80 percent of hospitals listed in the July 2007 U.S News and World Report ranking of America's Best Hospitals and in approximately 58 percent of all domestic operating rooms. In the last twelve months BIS technology was used in approximately 17 percent of all U.S. surgical procedures requiring general anesthesia or deep sedation. BIS technology is available in more than 160 countries. Aspect Medical Systems has OEM agreements with seven leading manufacturers of patient monitoring systems. The company is also investigating how other methods of analyzing brain waves may aid in the diagnosis and management of neurological diseases, including depression and Alzheimer's disease. For more information, visit Aspect's Web site at http://www.aspectmedical.com.

Safe Harbor Statement

Certain statements in this release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995 and may involve risks and uncertainties, including: statements regarding the expected benefits of the Company's BIS Education programs and the BIS family of product offerings, including the suggested benefits of BIS monitoring demonstrated in sponsored research studies of BIS monitoring in various clinical settings and patient populations; and the Company's belief that the market for BIS monitoring is continuing to grow globally. There are a number of important factors that could cause actual results to differ materially from those indicated by these forward-looking statements. For example, the Company may not achieve widespread market acceptance of its BIS monitoring technology among anesthesiologists and its BIS Education program may not achieve the Company's goal of enhancing the integration of BIS monitoring into patient care. The Company also faces other barriers to market penetration and acceptance. The Company may not be able to compete with new products or alternative techniques that may be developed by others, including third-party anesthesia monitoring products approved by the FDA, and also faces competitive and regulatory risks relating to its ability to successfully develop and introduce enhancements and new products, including products to aid in the treatment of neurological disorder. Cases of awareness with recall during monitoring with the BIS system and significant product liability claims are among the factors that could limit market acceptance. There are additional factors that could cause the Company's actual results to vary from its forward-looking statements, including without limitation those set forth under the heading "Risk Factors" in the Company's Annual Report on Form 10-K for the year ended December 31, 2006 and the Company's Quarterly Report on Form 10-Q for the fiscal quarter ended June 30, 2007, each as filed with the Securities and Exchange Commission. In addition, any forward-looking statements represent the Company's views only as of the date of this press release and should not be relied upon as representing the Company's views as of any subsequent date. While the Company may elect to update forward-looking statements in the future, it specifically disclaims any obligation to do so, even if its expectations change. Therefore, you should not rely on these forward-looking statements as representing the Company's views as of any date subsequent to the date of this press release.

Aspect and BIS are trademarks of Aspect Medical Systems, Inc. and are registered in the USA, EU and other countries. BIS VISTA, BIS VIEW and BISx, are trademarks of Aspect Medical Systems, Inc. All other trademarks, service marks and company names are the property of their respective owners.