Aspect Medical Systems, Inc. Reports Effectiveness of Shelf Registration Statement.

NORWOOD, Mass. -- Aspect Medical Systems, Inc. (NASDAQ: ASPM) reported today that on October 5, 2007, the U.S. Securities and Exchange Commission declared effective the shelf registration statement filed with the Commission on August 29, 2007, as amended on October 2, 2007, in connection with the registration for re-sale of an aggregate principal amount of $125 million of 2.50% Convertible Senior Notes due 2014, which Aspect Medical Systems issued in a private placement in June 2007, and shares of Aspect Medical Systems common stock, $0.01 par value, which are issuable upon conversion of the notes.

Under the shelf registration statement, the holders of the 2.50% Convertible Senior Notes due 2014, and the common stock which may be issued upon conversion of such notes, may sell these securities in one or more separate offerings with the size, price and terms to be determined at the time of sale.

Any offering of securities covered by the shelf registration statement may be made only by means of written prospectuses and prospectus supplements. This press release shall not constitute an offer to sell, or the solicitation of an offer to buy, nor shall there be any sale of these securities in any jurisdiction in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction.

A copy of the registration statement and prospectus relating to the re-sale of the 2.50% Convertible Senior Notes due 2014, and the common stock which may be issued upon conversion of such notes, may be obtained from Aspect Medical's Investor Relations Department, Aspect Medical Systems, Inc., One Upland Road, Norwood, Massachusetts 02062, telephone: [phone].

About the Company

Aspect Medical Systems, Inc. (NASDAQ: ASPM - News) is a global market leader in brain monitoring technology. To date, the Company's Bispectral Index (BIS) technology has been used to assess approximately 20 million patients and has been the subject of more than 2,800 published articles and abstracts. BIS technology is installed in approximately 80 percent of hospitals listed in the July 2007 U.S News and World Report ranking of America's Best Hospitals and in approximately 58 percent of all domestic operating rooms. In the last twelve months BIS technology was used in approximately 17 percent of all U.S. surgical procedures requiring general anesthesia or deep sedation. BIS technology is available in more than 160 countries. Aspect Medical Systems has OEM agreements with seven leading manufacturers of patient monitoring systems.

Safe Harbor Statement

Certain statements in this release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995 and may involve risks and uncertainties. There are a number of important factors that could cause actual results to differ materially from those indicated by these forward-looking statements, including those factors described under the heading "Risk Factors" in the Company's Quarterly Report on Form 10-Q for the quarter ended June 30, 2007, which is on file with the SEC.

In addition, the statements in this press release represent the Company's expectations and beliefs as of the date of this press release. The Company anticipates that subsequent events and developments may cause these expectations and beliefs to change. However, while the Company may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing the Company's expectations or beliefs as of any date subsequent to the date of this press release.

For further information regarding Aspect Medical Systems, Inc., visit the Aspect Medical Systems website at www.aspectmedical.com.