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As Founder Jim Lindelien Departs, Dr. Roland Luethy Applies Pharmaceutical Insight to Development of Accelerated Algorithms for TimeLogic DeCypher Solution.


Business Editors/Health & Medical Writers

BIOWIRE2K

CRYSTAL BAY, Nev.--(BUSINESS WIRE)--Feb. 27, 2003

TimeLogic(TM) announces that founder Jim Lindelien is leaving the company to pursue new opportunities. Lindelien started TimeLogic in 1994 and pioneered the engineering of the DeCypher(R) Accelerated Bioinformatics Solution. DeCypher efficiently speeds core bioinformatics tasks -- including BLAST, Smith-Waterman, and Hidden Markov Model A hidden Markov model (HMM) is a statistical model in which the system being modeled is assumed to be a Markov process with unknown parameters, and the challenge is to determine the hidden parameters from the observable parameters.  analysis -- through the use of FPGA (Field Programmable Gate Array) A type of gate array that is programmed in the field rather than in a semiconductor fab. Containing up to hundreds of thousands of gates, there are a variety of FPGA architectures on the market.  technology rather than a large collection of server CPUs. Lindelien most recently held the position of Chief Technology Officer at TimeLogic.

"We thank Jim for his vision in creating DeCypher and for helping build TimeLogic into a dominant player within life science computing computing - computer ," commented Rick MacDonald, TimeLogic President and COO. "As founder and primary shareholder, Jim is comfortable with TimeLogic's future prospects and has chosen this time to pursue other personal interests," MacDonald added.

TimeLogic's Senior Bioinformatics Research Scientist, Roland Luethy, Ph.D., continues to focus on development of additional algorithms for the DeCypher system. "We are excited to apply TimeLogic's acceleration technology to emerging drug discovery and genomics research problems," Luethy remarked. With over nine years of experience at Amgen Inc., Dr. Luethy has developed a wide range of algorithms for genomic and proteomic analysis, including protein structure prediction Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry. Its aim is the prediction of the three-dimensional structure of proteins from their amino acid sequences, sometimes including additional relevant information such as , protein threading and signal peptide A signal peptide is a short (3-60 amino acids long) peptide chain that directs the post-translational transport of a protein. Signal peptides may also be called targeting signals, signal sequences, transit peptides, or localization signals.  localization Customizing software and documentation for a particular country. It includes the translation of menus and messages into the native spoken language as well as changes in the user interface to accommodate different alphabets and culture. See internationalization and l10n. . He also led high throughput EST database projects and coordinated analysis of vast amount of proteomics data generated at Amgen. Dr. Luethy received his Ph.D. from University of Bern The University of Bern is a university in the Swiss capital of Bern. It was founded in 1834. As one of the German-speaking universities in Switzerland its official name is Universität Bern, although it is frequently referred to in the French form, Université de Berne.  in Switzerland in 1988.

About TimeLogic

With TimeLogic's leading-edge DeCypher technology, complex bioinformatics searches are compressed from hours to minutes, and multiple months to days. DeCypher brings the performance equivalent of hundreds to thousands of server CPUs, and enables drug discovery and genomics researchers to integrate multiple analysis techniques for more comprehensive scientific results.

TimeLogic has been accelerating discovery since 1996. DeCypher bioinformatics systems are in use by over 50 top biotechnology, pharmaceutical and agribusiness agribusiness

Agriculture operated by business; specifically, that part of a modern national economy devoted to the production, processing, and distribution of food and fibre products and byproducts.
 companies, as well as key academic and government research institutions worldwide. TimeLogic is headquartered at 22 State Route 28, Crystal Bay, NV 89402-0248. For more information, please contact Christopher Hoover, Director of Marketing (Tel: 775/832-3104, chrish@timelogic.com) or visit http://www.timelogic.com.
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Publication:Business Wire
Date:Feb 27, 2003
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