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ArthroCare Secures Exclusive Rights to Distribute Biocomposites' BiLok Absorbable Tissue Fixation Technology in United States.


Business Editors/Health/Medical Writers

SUNNYVALE, Calif.--(BUSINESS WIRE)--May 1, 2003

Agreement Enables ArthroCare to Provide Surgeons Worldwide a

Complete System of Tissue Anchors and Fixation Devices for Knee and

Shoulder Reconstructions

ArthroCare Corp. (Nasdaq:ARTC ARTC Arthrocare Corp (stock symbol)
ARTC Australian Rail Track Corporation
ARTC Air Route Traffic Control
ARTC Association de la Recherche Theatrale au Canada
ARTC Andean Root and Tuber Crops
), a multi-business medical device company that develops products based on its patented Coblation(R) technology, today announced it has secured exclusive rights to distribute Biocomposites' BiLok(R) absorbable tissue fixation technology in the United States United States, officially United States of America, republic (2005 est. pop. 295,734,000), 3,539,227 sq mi (9,166,598 sq km), North America. The United States is the world's third largest country in population and the fourth largest country in area. . Under this agreement, the first product to be marketed by ArthroCare will be the BiLok ACL See access control list.

1. ACL - Access Control List.
2. ACL - Association for Computational Linguistics.
3. ACL - A Coroutine Language.

A Pascal-based implementation of coroutines.

["Coroutines", C.D.
 Screw.

With BiLok, ArthroCare is able to provide surgeons worldwide a complete system for ligament and tendon reconstructions in the knee, significantly increasing the company's revenue per procedure in arthroscopic anterior cruciate ligament anterior cruciate ligament
n. Abbr. ACL
The cruciate ligament of the knee that crosses from the anterior intercondylar area of the tibia to the posterior part of the lateral condyle of the femur.
 (ACL) reconstructions and complementing the company's ACL reconstruction products acquired last October through its acquisition of Atlantech Medical Devices, Ltd.

ACL reconstructions are the most common surgical ligament and tendon procedures performed in the United States, with nearly 300,000 performed annually, often on high-profile athletes.

"We are pleased to have been granted exclusive rights to distribute the Biocomposites technology in the United States," said Michael A. Baker Michael Allen Baker (Captain, USN, Ret.) is the International Space Station Program Manager for International and Crew Operations, at NASA's Johnson Space Center. He is responsible for the coordination of program operations, integration and flight crew training and support , president and chief executive officer for ArthroCare. "We have been distributing the BiLok ACL Screw outside of this country for the past three years with great success, particularly in Europe. The U.S. distribution rights are an expansion of our original agreement with Biocomposites. We look forward to further leveraging the BiLok implant to complement and broaden our current ACL product set worldwide."

BiLok ACL Screw -- Turning Implants Into Bone

During ACL reconstruction surgery, a tendon is inserted into bone and secured using anchoring devices or screws, usually made of metal or single-polymer absorbable materials. Growth of healthy, new bone to secure the tendon during healing requires osteogenic osteogenic /os·te·o·gen·ic/ (-jen´ik) derived from or composed of any tissue concerned in bone growth or repair.

os·te·o·gen·ic or os·te·o·ge·net·ic
adj.
 cells, which need a biocompatible biocompatible /bio·com·pat·i·ble/ (-kom-pat´i-b'l) being harmonious with life; not having toxic or injurious effects on biological function.  scaffold onto which they can attach and proliferate. Extensive research shows the most biocompatible bone scaffolds are those based on calcium salts.

The BiLok ACL Screw is manufactured using a proprietary process where calcium salts are impregnated im·preg·nate  
tr.v. im·preg·nat·ed, im·preg·nat·ing, im·preg·nates
1. To make pregnant; inseminate.

2. To fertilize (an ovum, for example).

3.
 throughout the device and on the surface, where they are available as a scaffold. The result is an osteoconductive healing response that essentially converts the screw itself into bone. This process ultimately creates a stronger fixation of the tendon, permitting patients to more quickly return to normal activity and restoring the operative site to a more natural condition. In addition, the BiLok ACL Screw eliminates the need to remove an implant months after surgery, which is sometimes necessary with metal screws.

Biocomposites technology has been used clinically for more than four years. And, Biocomposites has compiled more than four years of human clinical data with significant, positive results.

"ArthroCare's past successes in the distribution of BiLok products in Europe will provide an excellent base for increasing their distribution to U.S. surgeons," said Biocomposites' managing director J. Stephen Bratt. "Our product development people will work closely with the ArthroCare team to expand the BiLok range of sports medicine sports medicine, branch of medicine concerned with physical fitness and with the treatment and prevention of injuries and other disorders related to sports. Knee, leg, back, and shoulder injuries; stiffness and pain in joints; tendinitis; "tennis elbow"; and  products."

In addition to ArthroCare's distribution of the BiLok ACL Screw, the agreement calls for other, new bioabsorbable products to be developed by Biocomposites and marketed by ArthroCare. These new products are expected to include innovative solutions for ligament and meniscus meniscus /me·nis·cus/ (me-nis´kus) pl. menis´ci   [L.] something of crescent shape, as the concave or convex surface of a column of liquid in a pipet or buret, or a crescent-shaped cartilage in the knee joint.  reconstruction and anchors for soft tissue fixation in the shoulder. More than a million patients undergo surgeries requiring these types of products in the United States annually.

ArthroCare will market the BiLok ACL Screw to arthroscopic surgeons through its U.S. distribution network.

ABOUT ARTHROCARE

ArthroCare Corp. (www.arthrocare.com), headquartered in Sunnyvale, Calif., is a multi-business medical device company that develops, manufactures and markets minimally invasive soft tissue surgical products based on its patented Coblation technology. Coblation uses low-temperature radiofrequency energy to gently and precisely dissolve rather than burn soft tissue, minimizing damage to healthy tissue. ArthroCare targets a multi-billion dollar market opportunity across several medical specialties, significantly improving surgical procedures and enabling new, minimally invasive procedures. ArthroCare's Coblation-based devices have been used in approximately two million surgical procedures worldwide. The company has developed and marketed Coblation-based products for arthroscopic, spine/neurologic, ear, nose and throat, cosmetic, urologic, gynecologic gynecologic /gy·ne·co·log·ic/ (gi?ne-) (jin?e-kah-loj´ik) pertaining to the female reproductive tract or to gynecology.  and laparoscopic/general surgical procedures, and continues research in other areas.

Safe Harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
 Statements

Except for historical information, this press release includes forward-looking statements. These statements include, but are not limited to, the expectations regarding trends in newly commercialized markets, the company's belief that certain surgical products and procedures will enhance achievement of the company's long-term potential, the sustainability of growth rates Growth Rates

The compounded annualized rate of growth of a company's revenues, earnings, dividends, or other figures.

Notes:
Remember, historically high growth rates don't always mean a high rate of growth looking into the future.
 in certain markets, the effect of anticipated government regulatory clearances, continued success of product diversification efforts, opportunities to execute strategic initiatives, and other statements that involve risks and uncertainties. These risks and uncertainties include, but are not limited to, the fact that the company's operating results will fluctuate, the market price of the company's stock may be highly volatile, the sustainability of the company's growth rate, continued success of market diversification efforts. These and other risks and uncertainties are detailed from time to time in the company's Securities and Exchange Commission filings, including ArthroCare's Form 10-K Form 10-K

A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information.


Form 10-K

See 10-K.
 for the year ended Dec. 31, 2002. Forward-looking statements are indicated by words or phrases such as "anticipates," "estimates," "projects," "believes," "intends," "expects," and similar words and phrases Words and Phrases®

A multivolume set of law books published by West Group containing thousands of judicial definitions of words and phrases, arranged alphabetically, from 1658 to the present.
. Actual results may differ materially from management plans.
COPYRIGHT 2003 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2003, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:May 1, 2003
Words:882
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