Applying genomic and proteomic microarray technology in drug discovery.RS419 2004-057042 0-8493-1469-0 Applying genomic and proteomic microarray technology in drug discovery. Matson, Robert S Robert, Henry Martyn 1837-1923. American army engineer and parliamentary authority. He designed the defenses for Washington, D.C., during the Civil War and later wrote Robert's Rules of Order (1876). Noun 1. . CRC (Cyclical Redundancy Checking) An error checking technique used to ensure the accuracy of transmitting digital data. The transmitted messages are divided into predetermined lengths which, used as dividends, are divided by a fixed divisor. Press, [c]2005 243 p. $149.95 A microarray is a collections of small spots of biological capture--such as DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. , an antibody, or a carbohydrate--organized on a planar A technique developed by Fairchild Instruments that creates transistor sublayers by forcing chemicals under pressure into exposed areas. Planar superseded the mesa process and was a major step toward creating the chip. substrate such as a glass microscope slide. The technique allows a global assessment of the cellular process, delivers digital information that can be assembled and used to quantify biological events and relations on an unprecedented scale, and quickly provides researchers with voluminous data in response to a biological query. Though array-based technologies are now being adopted in diverse fields, Matson, a senior scientist at a California company, emphasizes present and potential applications related to drug discovery, where he says microarrays continue to play significant and increasingly important roles. He discusses quantitative biology, commercial microarrays, supports and surface chemistry, arraying processes, microarray-based applications in gene expression, and protein microarray A protein microarray is a piece of glass on which different molecules of protein have been affixed at separate locations in an ordered manner thus forming a microscopic array. applications. |
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