Applied NeuroSolutions and Nanosphere Sign Research Agreement; Companies Seek to Develop Next-Generation Tests for Alzheimer's Disease.VERNON HILLS Vernon Hill II (born circa 1946) is the founder and former chairman, president, and chief executive officer of Commerce Bancorp and Commerce Bank of Cherry Hill Township, New Jersey. , Ill. & NORTHBROOK, Ill. -- Applied NeuroSolutions, Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :APNS APNS All Pakistan Newspapers Society APNS Alliance to Protect Nantucket Sound ), a Company focused on the development of an integrated product portfolio for the diagnosis and treatment of Alzheimer's disease Alzheimer's disease (ăls`hī'mərz, ôls–), degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia. , and Nanosphere, Inc., a nanotechnology-based molecular diagnostics company, today announced a research collaboration for the development of diagnostic tests for Alzheimer's disease. Today there are no FDA-approved diagnostic tests to detect Alzheimer's disease; it can only be confirmed post-mortem. A definitive diagnostic test may lead to earlier detection of the disease and enable better medical intervention as well as help distinguish Alzheimer's from other forms of age-related dementia. A diagnostic test could also greatly aid research and development of new pharmaceuticals to treat the disease. This research program will apply Nanosphere's proprietary Biobarcode(TM) technology for ultra-sensitive protein detection to Applied NeuroSolutions' proprietary biomarkers, which have been shown to be 85 to 95 percent accurate in the detection of Alzheimer's disease. Ultra-sensitive detection of these markers has the potential to lead to the next generation of diagnostic tests for Alzheimer's disease. "Nanosphere has developed a groundbreaking platform for the detection of nucleic acids Nucleic acids The cellular molecules DNA and RNA that act as coded instructions for the production of proteins and are copied for transmission of inherited traits. and proteins at extraordinary low concentrations, and we believe this collaboration could lead to better diagnostic tests for Alzheimer's disease, strengthening our product pipeline and potentially allowing us to utilize other bodily fluids for an Alzheimer's test," said John DeBernardis, Ph.D., President and Chief Executive Officer of Applied NeuroSolutions. "Applied NeuroSolutions has achieved significant progress with the development of its cerebrospinal fluid cerebrospinal fluid (CSF) Clear, colourless liquid that surrounds the brain and spinal cord and fills the spaces in them. It helps support the brain, acts as a lubricant, maintains pressure in the skull, and cushions shocks. (CSF Cerebrospinal Fluid (CSF) Analysis Definition Cerebrospinal fluid (CSF) analysis is a laboratory test to examine a sample of the fluid surrounding the brain and spinal cord. ) test to detect p-tau, a biomarker for Alzheimer's disease," said William Moffitt, President and Chief Executive Officer of Nanosphere, Inc. "Using our proprietary technology could lead to the development of a more sensitive and specific test for future clinical use, potentially leading to the earlier detection of Alzheimer's disease." About Applied NeuroSolutions Applied NeuroSolutions, Inc. (OTCBB:APNS) is developing products to diagnose and treat Alzheimer's disease based on a novel hypothesis of AD pathology. In partnership with Dr. Peter Davies For other persons of the same name, see Peter Davis. Peter Davies (born March 22, 1989) is a Welsh actor who has appeared in many minor roles in such BBC productions as Little Britain, Holy Cross, and the more recent Sweeney Todd. and a scientific team at Albert Einstein College of Medicine
The Albert Einstein College of Medicine (AECOM) is a graduate school of Yeshiva University. It is a private medical school located in the Jack and Pearl Resnick Campus of Yeshiva University in the Morris Park , Applied NeuroSolutions has developed a cerebrospinal fluid (CSF) test to detect Alzheimer's disease at a very early stage with 85%-95% accuracy in nearly 3,500 patient samples. There are approximately 2 million new patients annually worldwide who are candidates for an AD CSF diagnostic test, according to according to prep. 1. As stated or indicated by; on the authority of: according to historians. 2. In keeping with: according to instructions. 3. Datamonitor. The company is also developing a blood serum-based screening test, as well as a new class of therapeutics to treat AD. Alzheimer's disease currently afflicts over 4 million Americans, and the market for AD therapy is expected to grow to 21 million patients by 2010 in the seven major pharmaceutical markets (USA, France, Germany, Italy, Spain, U.K. and Japan) according to BioPortfolio, Ltd. There are currently no FDA-approved diagnostic tests to detect Alzheimer's disease. For more information, visit www.appliedneurosolutions.com. About Nanosphere, Inc. Nanosphere is a life sciences company applying proprietary nanotechnology to create new standards in medical care and public safety. With a universal Verigene(TM) product platform for the detection of nucleic acids and proteins at extraordinarily low concentrations, Nanosphere is rapidly advancing the development of assays for genomic and proteomic research, clinical laboratories and point-of-care markets. The privately held company privately held company A firm whose shares are held within a relatively small circle of owners and are not traded publicly. is based in Northbrook, Illinois. Additional information is available at www.nanosphere.us. This press release contains forward-looking statements forward-looking statement A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections. . Applied NeuroSolutions wishes to caution the readers of this press release that actual results may differ from those discussed in the forward-looking statements and may be adversely affected by, among other things, the risks associated with new product development and commercialization, clinical trials, intellectual property, regulatory approvals, potential competitive offerings, and access to capital. For further information, please visit the company's websites at www.appliedneurosolutions.com, and review the company's filings with the Securities and Exchange Commission. |
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