Applied DNA Sciences Signs Cooperative Agreement with Department of Energy.

LOS ANGELES -- Applied DNA Sciences, Inc. (OTCBB:APDN) signed a Cooperative Research and Development Agreement (CRADA) with the Department of Energy's laboratory in Idaho to develop the next generation of rapid analytical tools used for DNA analysis, to enhance speed, efficiency and expand the utility of the novel Applied DNA security marker technology.

Consistent with the National Security mission of the DOE laboratories, and because of their unique equipment and capabilities, scientists and engineers at the Idaho lab will work to improve DNA forensic testing tools that build upon Polymerase Chain Reaction (PCR-based) detection of DNA recovered from security marked materials. Providing greater security for official documents, currency, textiles and drug packaging are the goals of this program. Articles spiked with the harmless botanical DNA marker, will help to thwart counterfeiting, grey market corruption and enhance the accounting of sensitive or secure materials.

"Applied DNA Sciences has developed a proprietary and exclusive method to stabilize botanical DNA to survive harsh industrial processing and endure years of use. We have enlisted the unique expertise of the national laboratories to make DNA work as a broadly adopted, practical security solution, which requires a method of detection and analysis that is faster and cheaper over that which is commercially available today, said Paul Reep, Chief Technology Officer.

In February of this year Applied DNA Sciences executed a similar research agreement with the Agricultural Research Service (USDA-ARS) Cotton Quality Research Station in Clemson, South Carolina, to develop methods of integrating the DNA marker into textile materials. The marker system technology has undergone rapid development since executing the agreement and will soon produce a commercially available security solution to the industry. According to the International Anti-counterfeit Coalition, in 2002 counterfeit textiles and apparel cost the U.S. economy $98M. The International Chamber of Commerce suggests the global problem was $350B for that same year, representing 7% of world trade.

Contacts: Applied DNA Sciences, Inc. Paul Reep, 310-860-1362, ([e-mail]) Department of Energy: Keith Arterburn, 208-526-4845, [e-mail], Tom Harrison, 208-526-1710 ([e-mail]) and Tom Ulrich, 208-526-7282, ([e-mail])

About Applied DNA Sciences, Inc.

Applied DNA Sciences, Inc. provides proprietary DNA-embedded security solutions, using plant (non-human) DNA, that verify authenticity and protect corporate and government agencies from counterfeiting, fraud, piracy, product diversion, identity theft and unauthorized intrusion. Applied DNA Sciences has an exclusive licensing and partnership agreement covering North America and Europe with Biowell Technology, Inc. of Taiwan whose technology is protected by 10 international patents. (http://www.biowell.com.tw/eng). Applied DNA Sciences, Inc., 9229 West Sunset Boulevard Los Angeles, CA 90069; Tel: [phone]; Fax: [phone]. www.ADNAS.com.

Except for historical information contained herein, the matters set forth in this press release, such as statements relating to the Company's ability to drive technological developments and the acceptance and timing of product introductions, are forward-looking statements that are subject to risks and uncertainties, including timely development and acceptance of new products, the impact of competitive products and pricing, the timely development and release of products by suppliers and other risks detailed in the Company's Registration Statement filed with the SEC.