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Applied Biosystems and Integromics to Offer Integrated Real-Time PCR and Data Analysis Platform.


First-of-Its Kind Solution Combines Industry-Leading Software and Instrument Systems to Aid Researchers in Studying Gene Expression Data

FOSTER CITY, Calif. & GRANADA, Spain -- Applied Biosystems Applied Biosystems, Inc. (formerly NASDAQ: ABIO) is the original name of a pioneer biotechnology company founded in 1981 in Foster City, California, among the Silicon Valley cities of the southern San Francisco Bay Area.  (NYSE NYSE

See: New York Stock Exchange
:ABI Abi (ā`bī) [short for Abijah], in the Bible, King Hezekiah's mother.


(Application Binary Interface) A specification for a specific hardware platform combined with the operating system.
), an Applera Corporation business, and Integromics S.L., a scientific IT company, today announced the availability of an integrated solution for analyzing real-time PCR PCR polymerase chain reaction.

PCR
abbr.
polymerase chain reaction


Polymerase chain reaction (PCR) 
 data. The companies have created a first-of-its-kind solution that integrates advanced bioinformatics software with high-throughput real-time PCR instrument systems. The resulting platform is expected to aid life-scientists in performing data analysis in a variety of research projects.

This unique solution integrates Integromics' Real-Time StatMiner[TM] software with any combination of Applied Biosystems' line of real-time PCR systems. The joint solution will be co-marketed exclusively by the two companies.

Real-time PCR is a laboratory method used to detect and determine the amount of nucleic acids Nucleic acids
The cellular molecules DNA and RNA that act as coded instructions for the production of proteins and are copied for transmission of inherited traits.
 present in samples. Data generated by real-time PCR systems can help life scientists to assess variations in gene expression. This method is commonly used to study the development of disease, differentiation in stem cells stem cells, unspecialized human or animal cells that can produce mature specialized body cells and at the same time replicate themselves. Embryonic stem cells are derived from a blastocyst (the blastula typical of placental mammals; see embryo), which is very young , or the toxic effects of drugs. Another emerging application of real-time PCR is for the study of microRNAs, and understanding their role as genetic markers genetic marker
n.
A gene phenotypically associated with a particular, easily identified trait and used to identify an individual or cell carrying that gene.
 used in disease classification and drug discovery.

As real-time PCR expands in its applications, researchers are looking for Looking for

In the context of general equities, this describing a buy interest in which a dealer is asked to offer stock, often involving a capital commitment. Antithesis of in touch with.
 integrated, high-throughput data analysis tools that work seamlessly with their instrument systems. Often times, they develop their own software programs that are only loosely integrated with their systems, requiring bioinformatics expertise to manage them. The Applied Biosystems-Integromics solution is the first commercially available offering that integrates the system that generates the data with the software that is used to analyze it.

The solution works by capturing raw data from an Applied Biosystems real-time PCR system. The StatMiner software then enables visualization and analysis of the data generated during the real-time PCR process through a combination of interactive data visualization See information visualization.  tools, advanced statistical analysis and data mining. Users of the software are guided through the analysis process, enabling the use of the software by non-experts in bioinformatics.

"Advanced bioinformatics tools that help researchers in the analysis and interpretation of raw gene expression data are becoming a key complement to the advances in instrumentation and reagents," said Vicente R. Carro, chief executive officer of Integromics S.L. "By combining Applied Biosystems' leadership in real-time PCR with Integromics' expertise in bioinformatics, we have created a solution that provides our mutual customers a better way to manage their high-throughput projects and analyze their real-time PCR data."

Integromics is an innovative developer of data management, integration and analysis software used in genomics and proteomics research. The company's Real-Time StatMiner Software is a stand alone application which is also available as an integrated guide within other leading laboratory data analysis systems.

Applied Biosystems is a global leader in the development and commercialization of instrument-based systems, consumables, software, and services for the life-science market. The company is an industry leader in driving innovation in the life science industry through initiatives such the BioIT Alliance and its own Software Development Program, in which its genetic analysis data file formats and data file converters are available to independent software vendors such as Integromics. This program facilitates the development of next-generation bioinformatics applications that can advance productivity and data sharing The ability to share the same data resource with multiple applications or users. It implies that the data are stored in one or more servers in the network and that there is some software locking mechanism that prevents the same set of data from being changed by two people at the same time.  on Applied Biosystems' industry leading genetic analyzers and real-time PCR sequence detection systems that include the Applied Biosystems 7900HT Fast Real-Time PCR System, 7500 Real-Time PCR System, 7500 Fast Real-Time PCR System, StepOne[TM] Real-Time PCR System, and StepOnePlus[TM] Real-Time PCR System.

"Applied Biosystems is focused on creating a more collaborative environment that enables independent software developers to bring to market innovative new applications that enhance the value of our best-in-class instrument systems," said John Gerace, vice president and general manager for Applied Biosystems' sequence detection business. "Working in collaboration with Integromics we have created a solution that supports our mutual customers in their gene expression research by enabling them to turn their data into meaningful information for use in a range of research projects including drug discovery and development."

For more information on Applied Biosystems' complete line of workflow solutions for real-time PCR please visit http://www.appliedbiosystems.com.

For more information about Integromics and the Real-Time StatMiner software please visit http://www.integromics.com/StatMiner.php.

About Applera Corporation and Applied Biosystems

Applera Corporation consists of two operating groups. Applied Biosystems serves the life science industry and research community by developing and marketing instrument-based systems, consumables, software, and services. Customers use these tools to analyze nucleic acids (DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 and RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
), small molecules, and proteins to make scientific discoveries and develop new pharmaceuticals. Applied Biosystems' products also serve the needs of some markets outside of life science research, which we refer to as "applied markets," such as the fields of: human identity testing (forensic and paternity testing paternity testing

see parentage testing.
); biosecurity, which refers to products needed in response to the threat of biological terrorism Noun 1. biological terrorism - terrorism using the weapons of biological warfare
bioterrorism

act of terrorism, terrorism, terrorist act - the calculated use of violence (or the threat of violence) against civilians in order to attain goals that are
 and other malicious, accidental, and natural biological dangers; and quality and safety testing, such as testing required for food and pharmaceutical manufacturing. Applied Biosystems is headquartered in Foster City, CA, and reported sales of approximately $2.1 billion during fiscal 2007. Celera is a diagnostics business delivering personalized disease management solutions through a combination of tests and services based on proprietary genetics discovery platforms. The business is developing diagnostic products that predict disease risk and optimize therapy selection and patient outcomes, based on the discovery and validation of novel markers in complex diseases such as cardiovascular disease Cardiovascular disease
Disease that affects the heart and blood vessels.

Mentioned in: Lipoproteins Test

cardiovascular disease 
, breast cancer, and liver and autoimmune diseases Autoimmune diseases
A group of diseases, like rheumatoid arthritis and systemic lupus erythematosus, in which immune cells turn on the body, attacking various tissues and organs.

Mentioned in: Complement Deficiencies, Premature Menopause
. Celera also maintains a strategic alliance with Abbott for the development and commercialization of some of its molecular diagnostic products. Information about Applera Corporation, including reports and other information filed by the company with the Securities and Exchange Commission, is available at http://www.applera.com, or by telephoning 800.762.6923. Information about Applied Biosystems is available at http://www.appliedbiosystems.com.

About Integromics S.L.

Integromics, S.L., winner of the Frost & Sullivan award A Sullivan Award may refer to:
  • Algernon Sydney Sullivan Award or Mary Mildred Sullivan Award; awarded at 29-grantee institutions of the Algernon Sydney Sullivan Foundation.
 2007 in the category "Product Innovation," provides IT solutions for Life Sciences (Genomics and Proteomics). In the post-genomic era, Integromics S.L. offers state-of-the-art products, services and training in two strategic areas: data management/integration and intelligent data analysis. The company has developed a network of collaborations both in industry and academia to provide complete technological solutions that will help our clients to achieve their goals. Integromics S.L, was founded in 2002 and is based in Granada, Spain, with offices in Madrid (Spain) and Philadelphia (USA). Integromics Inc. a wholly owned subsidiary Wholly Owned Subsidiary

A subsidiary whose parent company owns 100% of its common stock.

Notes:
In other words, the parent company owns the company outright and there are no minority owners.
 which was established in 2007. For more information: www.integromics.com.

Applied Biosystems Forward Looking Statements

Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as "should, "planned," and "expect," among others. These forward-looking statements forward-looking statement

A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections.
 are based on Applera Corporation's current expectations. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995 provides a "safe harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
" for such forward-looking statements. In order to comply with the terms of the safe harbor, Applera Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. These factors include but are not limited to: (1) rapidly changing technology and dependence on the development and customer acceptance of new products; (2) sales dependent on customers' capital spending capital spending

Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years.
 policies and government-sponsored research; and (3) other factors that might be described from time to time in Applera Corporation's filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and Applera does not undertake any duty to update this information, including any forward-looking statements, unless required by law.

For Research Use Only. Not for use in diagnostic procedures.

Applera, Applied Biosystems, and AB (Design) are registered trademarks of Applera Corporation or its subsidiaries in the U.S. and/or certain other countries.

Real-Time StatMiner is a registered trademark of Integromics, S.L. in the U.S. and/or certain other countries.

TaqMan is a registered trademark of Roche Molecular Systems, Inc.

(c)Copyright 2007. All Rights Reserved.
COPYRIGHT 2007 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved.

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Date:Dec 13, 2007
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