Applied Biosystems Launches Mouse Genome Microarray.Business Editors/Health/Medical Writers BIOWIRE2K FOSTER CITY, Calif.--(BUSINESS WIRE)--May 25, 2004 New Microarray Provides the Most Comprehensive Source of Mouse Genomic Data Combined With a High Sensitivity, Integrated System for Gene Expression Analysis Applied Biosystems Applied Biosystems, Inc. (formerly NASDAQ: ABIO) is the original name of a pioneer biotechnology company founded in 1981 in Foster City, California, among the Silicon Valley cities of the southern San Francisco Bay Area. Group (NYSE NYSE See: New York Stock Exchange :ABI Abi (ā`bī) [short for Abijah], in the Bible, King Hezekiah's mother. (Application Binary Interface) A specification for a specific hardware platform combined with the operating system. ), an Applera Corporation business, today announced the commercial availability of the Applied Biosystems Mouse Genome Survey Microarray for use with its recently introduced Expression Array System, a highly sensitive Adj. 1. highly sensitive - readily affected by various agents; "a highly sensitive explosive is easily exploded by a shock"; "a sensitive colloid is readily coagulated" gene expression detection system that detects more genes and achieves more than a 10-fold increase in sensitivity for the detection of low expressed genes when compared to conventional fluorescent microarrays. "The Applied Biosystems Mouse Genome Survey Microarray complements our recently commercialized Human Genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes. Survey Microarray and is a further example of our commitment to provide superior performance for the study of genome-wide expression analysis," said Michael W. Hunkapiller, Ph.D., President of Applied Biosystems. "Researchers now have the most comprehensive, integrated solution for mouse expression analysis, including the ability to easily move from whole-genome analysis to gene quantification and single-gene analysis using our Mouse Expression Array System in conjunction with our TaqMan(R) Mouse Gene Expression Assays, TaqMan(R) Low Density Array, Celera Discovery System, and real-time PCR PCR polymerase chain reaction. PCR abbr. polymerase chain reaction Polymerase chain reaction (PCR) systems." The Applied Biosystems Mouse Genome Survey Microarray contains probes representing a complete, annotated, and fully curated set of approximately 32,000 mouse genes from the public and Celera databases. Employing the same highly sensitive chemiluminescence chemiluminescence /chemi·lu·mi·nes·cence/ (kem?i-loo?mi-nes´ens) luminescence produced by direct transformation of chemical energy into light energy. technology and well-defined, 60mer probe lengths as the Applied Biosystems Human Genome Survey Microarray, the Mouse Genome Survey Microarray provides the most comprehensive source of mouse genomic data for researchers studying the mouse, an important animal model of disease used also for safety assessment of therapeutics in toxicology studies. In addition, the annotation file supplied with the mouse microarray provides pre-computed human-mouse ortholog pairs for each gene when available. By obtaining a license to the Celera Discovery System(TM) online platform, researchers using the Celera Map Viewer can access graphical displays to compare human and mouse genes within their genomic context, and to identify genes located on the same chromosome and whether there is demonstrable linkage between them. The Applied Biosystems Rat Genome Survey Microarray is in development, and is expected to be available later this calendar year. For more information about the Applied Biosystems Mouse Expression Array System, please visit http://info.appliedbiosystems.com/eas. About Applera Corporation and Applied Biosystems Applera Corporation consists of two operating groups. The Applied Biosystems Group serves the life science industry and research community by developing and marketing instrument-based systems, consumables, software, and services. Customers use these tools to analyze nucleic acids Nucleic acids The cellular molecules DNA and RNA that act as coded instructions for the production of proteins and are copied for transmission of inherited traits. (DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. and RNA RNA: see nucleic acid. RNA in full ribonucleic acid One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic ), small molecules, and proteins to make scientific discoveries, develop new pharmaceuticals, and conduct standardized testing. Applied Biosystems is headquartered in Foster City, CA, and reported sales of $1.7 billion during fiscal 2003. The Celera Genomics Group (NYSE:CRA See Community Reinvestment Act. ), located in Rockville, MD, and South San Francisco South San Francisco, city (1990 pop. 54,312), San Mateo co., W Calif.; inc. 1908. South San Francisco has several industrial parks; its manufactures include medical supplies and equipment, foods, paint, paper products, consumer goods, and clothing. , CA, is engaged principally in integrating advanced technologies to discover and develop new therapeutics. Celera intends to leverage its proteomic, bioinformatic, and genomic capabilities to identify and validate drug targets, and to discover and develop new therapeutics. Its Celera Discovery System(TM) online platform, marketed exclusively by Applied Biosystems, is an integrated source of information based on the human genome and other biological and medical sources. Celera Diagnostics, a 50/50 joint venture between Applied Biosystems and Celera Genomics, is focused on discovery, development, and commercialization of novel diagnostic products. Information about Applera Corporation, including reports and other information filed by the company with the Securities and Exchange Commission, is available at http://www.applera.com, or by telephoning 800-762-6923. Information about Applied Biosystems is available at http://www.appliedbiosystems.com/. Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as "believe," "expect," "plans," and "should" among others. These forward-looking statements are based on Applera Corporation's current expectations. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995 provides a "safe harbor Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. " for such forward-looking statements. In order to comply with the terms of the safe harbor, Applera Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. These factors include but are not limited to (1) rapidly changing technology and dependence on the development of new products; (2) ability to integrate the Applied Biosystems Expression Array System with other Applied Biosystems products and services; (3) Applied Biosystems' dependence on the operation of computer hardware, software, and Internet applications and related technology; (4) unproven use of genomics information to develop or commercialize products; (5) market adoption of the technology; (6) claims for patent infringement patent infringement n. the manufacture and/or use of an invention or improvement for which someone else owns a patent issued by the government, without obtaining permission of the owner of the patent by contract, license or waiver. ; and (7) other factors that might be described from time to time in Applera Corporation's filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and Applera does not undertake any duty to update this information, including any forward-looking statements, unless required by law. For Research Use Only. Not for use in diagnostic procedures. ABI PRISM and Applied Biosystems are registered trademarks and AB (Design), Applera, Celera, Celera Diagnostics, Celera Discovery System, and Celera Genomics are trademarks of Applera Corporation and its subsidiaries in the U.S. and/or certain other countries. TaqMan is a registered trademark of Roche Molecular Systems, Inc. |
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