Applied Biosystems Announces Enhancements to Its Online Research Offerings to Better Enable Genetic Variation and Disease Association Studies.Business Editors/Health/Medical Writers BIOWIRE2K FOSTER CITY, Calif.--(BUSINESS WIRE)--March 10, 2004 Researchers Can Now Search for and Order Assays for High-Throughput SNP SNP Scottish National Party Noun 1. SNP - (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily Genotyping and Resequencing, Access Annotated Rat Genome Applied Biosystems Applied Biosystems, Inc. (formerly NASDAQ: ABIO) is the original name of a pioneer biotechnology company founded in 1981 in Foster City, California, among the Silicon Valley cities of the southern San Francisco Bay Area. Group (NYSE NYSE See: New York Stock Exchange :ABI Abi (ā`bī) [short for Abijah], in the Bible, King Hezekiah's mother. (Application Binary Interface) A specification for a specific hardware platform combined with the operating system. ), an Applera Corporation business, today announced a series of enhancements to its two online research resources, the free myScience(SM) research environment within the Applied Biosystems Web site and the subscription-based Celera Discovery System(TM) (CDS) online platform. These enhancements now give users the ability to design and order custom SNPlex(TM) genotyping assays to compare genetic differences and identify disease-associated genes. Researchers can now also search for and order the recently released VariantSEQr(TM) resequencing product sets to identify specific genetic variations in genes that may cause or contribute to a disease state. myScience provides users of the SNPlex(TM) Genotyping System with a simple entry point for submitting SNPs to the SNPlex(TM) System's assay design pipeline. Users can archive design reports and access them from the password protected myScience workspace. To order resequencing sets for the VariantSEQr(TM) Resequencing System, researchers can search in the myScience research environment under gene names, symbols, or chromosomal position. Graphical viewers allow users to more easily choose and order the most appropriate sets to meet their research needs. The latest release of the Celera Discovery System(TM) (CDS) online platform provides additional proprietary content, integration of genomic data, and viewer functionality. In addition to Celera's human and mouse genomic data, CDS now includes Celera's genome assembly and annotation content for the rat, a major mammalian model organism A model organism is a species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms. . Applied Biosystems has extended the interactive CDS graphical viewer to allow users to quickly visualize assembly-to-assembly differences between species or between public and Celera assemblies of the same species. A further enhancement of the graphical viewer enables researchers to add their own data, thereby graphically integrating their data with Celera and public data. Furthermore, the VariantSEQr(TM) resequencing product sets and the SNPlex(TM) System design and ordering pipeline are also now accessible through CDS. "With these enhancements, myScience and CDS provide a more robust and differentiated set of online information resources (1) The data and information assets of an organization, department or unit. See data administration. (2) Another name for the Information Systems (IS) or Information Technology (IT) department. See IT. and e-commerce tools to support our customers and facilitate the selection and ordering of our new reagent products," said Michael W. Hunkapiller, Ph.D., President of Applied Biosystems. "The new features within the myScience research environment offer a simple way to integrate experimental workflows both online and at the lab bench by linking high-quality biological information directly with the ready-to-use assays for gene expression, genotyping, resequencing, and protein expression studies." "Furthermore, the additional assembly and annotation of the rat genome provides CDS subscribers greater comparative genomics Comparative genomics is the study of relationships between the genomes of different species or strains. Comparative genomics is an attempt to take advantage of the information provided by the signatures of selection to understand the function and evolutionary processes that act on capabilities that should further advance functional genomics Noun 1. functional genomics - the branch of genomics that determines the biological function of the genes and their products genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences) and proteomics research," said Dr. Hunkapiller. About myScience(SM) myScience(SM) is a free, online life science research environment within the Applied Biosystems Web site for the design and analysis of genomic based experiments. For more information visit http://myscience.appliedbiosystems.com/. About the Celera Discovery System(TM) (CDS) Online Platform CDS is a web-based discovery platform that provides scientists with access to a comprehensive source of integrated, curated, and validated proprietary and public biological data, including annotated human, mouse, and rat genomes. More than 250 institutions worldwide currently subscribe to Verb 1. subscribe to - receive or obtain regularly; "We take the Times every day" subscribe, take buy, purchase - obtain by purchase; acquire by means of a financial transaction; "The family purchased a new car"; "The conglomerate acquired a new company"; CDS, including pharmaceutical and biotechnology companies Top 100 Biotechnology Companies The following is a list of the top 100 biotechnology companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies. , as well as academic organizations. For more information visit http://www.celeradiscoverysystem.com/. About Applera Corporation and Applied Biosystems Applera Corporation consists of two operating groups. The Applied Biosystems Group serves the life science industry and research community by developing and marketing instrument-based systems, consumables, software, and services. Customers use these tools to analyze nucleic acids Nucleic acids The cellular molecules DNA and RNA that act as coded instructions for the production of proteins and are copied for transmission of inherited traits. (DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. and RNA RNA: see nucleic acid. RNA in full ribonucleic acid One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic ), small molecules, and proteins to make scientific discoveries, develop new pharmaceuticals, and conduct standardized testing. Applied Biosystems is headquartered in Foster City, CA, and reported sales of $1.7 billion during fiscal 2003. The Celera Genomics Group (NYSE:CRA See Community Reinvestment Act. ), located in Rockville, MD, and South San Francisco South San Francisco, city (1990 pop. 54,312), San Mateo co., W Calif.; inc. 1908. South San Francisco has several industrial parks; its manufactures include medical supplies and equipment, foods, paint, paper products, consumer goods, and clothing. , CA, is engaged principally in integrating advanced technologies to discover and develop new therapeutics. Celera intends to leverage its proteomic, bioinformatic, and genomic capabilities to identify and validate drug targets, and to discover and develop new therapeutics. Its Celera Discovery System(TM) online platform, marketed exclusively by Applied Biosystems, is an integrated source of information based on the human genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes. and other biological and medical sources. Celera Diagnostics, a 50/50 joint venture between Applied Biosystems and Celera Genomics, is focused on discovery, development, and commercialization of novel diagnostic products. Information about Applera Corporation, including reports and other information filed by the company with the Securities and Exchange Commission, is available at http://www.applera.com, or by telephoning 800-762-6923. Information about Applied Biosystems is available at http://www.appliedbiosystems.com/. Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as "believe," "expect," "should," "anticipate," and "planned," among others. These forward-looking statements are based on Applera Corporation's current expectations. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995 provides a "safe harbor Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. " for such forward-looking statements. In order to comply with the terms of the safe harbor, Applera Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. These factors include but are not limited to: (1) rapidly changing technology could adversely affect demand for Applied Biosystems' products, and its business is dependent on development of new products; (2) uncertainty of successful integration of the myScience(SM) research environment and the Celera Discovery System(TM) online platform with Applied Biosystems' products and market acceptance and adoption of those products; (3) Applied Biosystems' sales are dependent on customers' capital spending capital spending Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years. policies and government-sponsored research; (4) dependence on the operation of computer hardware, software, and Internet applications and related technology for its businesses, particularly those focused on the development and marketing of information-based products and services (5) other factors that might be described from time to time in Applera Corporation's filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and Applera does not undertake any duty to update this information, including any forward-looking statements, unless required by law. Applied Biosystems and Celera are registered trademarks and Applera, Celera Diagnostics, Celera Discovery System, Celera Genomics, myScience, SNPlex, and VariantSEQr are trademarks of Applera Corporation or its subsidiaries in the U.S. and/or certain other countries. |
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