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Applied Biosystems Announces Commercial Availability of Rapid Avian Influenza Detection Kits in Europe, Asia and Africa.


WARRINGTON, England -- Assay Can Be Run on More Than 1,400 Applied Biosystems Applied Biosystems, Inc. (formerly NASDAQ: ABIO) is the original name of a pioneer biotechnology company founded in 1981 in Foster City, California, among the Silicon Valley cities of the southern San Francisco Bay Area.  Instruments in Public Health Laboratories across Europe, Asia and Africa

Applied Biosystems (NYSE NYSE

See: New York Stock Exchange
:ABI Abi (ā`bī) [short for Abijah], in the Bible, King Hezekiah's mother.


(Application Binary Interface) A specification for a specific hardware platform combined with the operating system.
), an Applera Corporation business, today announced the commercial availability in Europe, Asia, and Africa of its TaqMan(R) Influenza A/H A/H Ampere/Hour
A/H Air Handling
5 Detection Kit, which is capable of rapidly and reliably detecting multiple strains of avian influenza avian influenza: see influenza.  in laboratory samples. This test is not currently available for sale in the United States.

Applied Biosystems' avian influenza kits can detect the presence of the avian influenza virus in as few as two and a half hours. In comparison, traditional cell culture testing takes from 2-10 days to confirm avian influenza infections. The Applied Biosystems kits include standardized reagents and an accompanying protocol run on real-time PCR PCR polymerase chain reaction.

PCR
abbr.
polymerase chain reaction


Polymerase chain reaction (PCR) 
 (polymerase chain reaction polymerase chain reaction (pŏl`ĭmərās') (PCR), laboratory process in which a particular DNA segment from a mixture of DNA chains is rapidly replicated, producing a large, readily analyzed sample of a piece of DNA; the process is ) platforms, a technology widely used by life science researchers.

"We are delivering on the European, Asian, and African public health community's call for an early warning system for avian influenza," said Lars Holmkvist, President of Applied Biosystems, Europe. "Applied Biosystems' detection kit can detect infected samples in a matter of hours, not days, thereby speeding the public health response to avian flu outbreaks."

The kits, which can detect a broad range of viral strains, have been tested for accuracy against recent samples of avian influenza in collaboration with the following laboratories:

--Robert Koch Institute, Germany

--Avian Influenza Reference Veterinary Lab, Italy

--National Public Health Institute, Finland

--Ministry of Agriculture, Turkey

"Due to the geographical variability and frequent mutation of the avian influenza virus, detection technologies need to be tested against as many samples from as many different regions as possible," stated Dr. Brunhilde Schweiger of the National Reference Center for Influenza at the Robert Koch Institute in Germany. "Based on tests performed in our lab for detection of the H5 virus and differentiation from other influenza viruses, we are confident that Applied Biosystems' assays can quickly detect currently circulating strains of the virus with a high degree of reliability."

The Applied Biosystems TaqMan(R) Influenza A/H5 Detection Kits, which are manufactured in Warrington, England, are commercially available in Europe, Asia and Africa and have already been shipped to public health departments and veterinary laboratories in many European countries, including Switzerland, Finland, Germany, Italy, Poland, as well as several countries in Africa and the Middle East.

Applied Biosystems currently has an installed base of over 1,400 real-time PCR platforms in public health laboratories across Europe, Asia, and Africa capable of running the avian influenza TaqMan(R) assay. Today's announcement is part of a broader Applied Biosystems international initiative to ensure that detection kits and up-to-date genomic data are available for priority epidemiology studies related to infectious disease Infectious disease

A pathological condition spread among biological species. Infectious diseases, although varied in their effects, are always associated with viruses, bacteria, fungi, protozoa, multicellular parasites and aberrant proteins known as prions.
 threats.

To ensure availability of the kits in the event of an outbreak, Applied Biosystems intends to stockpile materials in the United Kingdom and Japan to enable a more rapid response to kit production and distribution.

Applied Biosystems Global Infectious Disease Identification Initiative

Through its global installed base of life sciences research systems, Applied Biosystems has been contributing toward public health preparedness and life science knowledge for nearly 25 years. The goal of Applied Biosystems' Global Infectious Disease Identification Initiative is to enable a comprehensive biosecurity infrastructure to help protect the public from emerging man-made and natural infectious disease threats, including avian influenza, anthrax anthrax (ăn`thrăks), acute infectious disease of animals that can be secondarily transmitted to humans. It is caused by a bacterium (Bacillus anthracis , tularemia tularemia (tlərē`mēə) or rabbit fever, acute, infectious disease caused by Francisella tularensis (Pasteurella tularensis). , plague, and other priority pathogens. By combining scientific expertise, genetic analysis systems and identification kit development with global distribution channels, Applied Biosystems intends to deliver standardized and reliable biosecurity solutions for infectious disease identification.

For Research Use Only. Not for Use in Diagnostic Procedures.

Applied Biosystems' influenza detection products are for research and epidemiological use only in countries outside of the United States. They have not been cleared or approved by the United States Food and Drug Administration United States Food and Drug Administration (FDA),
n.pr a unit of the Public Health Service created to protect the health of the nation against impure and unsafe foods, drugs, and cosmetics.
 or any other regulatory agency regulatory agency

Independent government commission charged by the legislature with setting and enforcing standards for specific industries in the private sector. The concept was invented by the U.S.
, or under the European IVD (Interactive VideoDisc) See interactive video.  Directive, for human diagnostic or other clinical use, and are not intended and should not be used for human diagnostic or any other clinical purposes. TaqMan(R) Influenza A/H5 Detection Kits and Applied Biosystems' other influenza detection kits are not for sale in the United States.

About Applera Corporation and Applied Biosystems

Applera Corporation consists of two operating groups. The Applied Biosystems Group serves the life science industry and research community by developing and marketing instrument-based systems, consumables, software, and services. Customers use these tools to analyze nucleic acids Nucleic acids
The cellular molecules DNA and RNA that act as coded instructions for the production of proteins and are copied for transmission of inherited traits.
 (DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 and RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
), small molecules, and proteins to make scientific discoveries and develop new pharmaceuticals. Applied Biosystems' products also serve the needs of some markets outside of life science research, which we refer to as "applied markets," such as the fields of: human identity testing (forensic and paternity testing paternity testing

see parentage testing.
); biosecurity, which refers to products needed in response to the threat of biological terrorism and other malicious, accidental, and natural biological dangers; and quality and safety testing, for example in food and the environment. Applied Biosystems is headquartered in Foster City, CA, and reported sales of nearly $1.8 billion during fiscal 2005. The Celera Genomics Group is focused on discovery, development, and commercialization of diagnostic products as well as leveraging its proteomic, bioinformatic, and genomic capabilities to identify and validate drug targets, and is also seeking to advance therapeutic antibody and selected small molecule drug programs in collaboration with global technology and market leaders. Information about Applera Corporation, including reports and other information filed by the company with the Securities and Exchange Commission, is available at http://www.applera.com, or by telephoning 800.762.6923. Information about Applied Biosystems is available at http://www.appliedbiosystems.com.

Applied Biosystems Forward-Looking Statements

Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as "intends," "expects," "plans," and "should" among others. These forward-looking statements are based on Applera Corporation's current expectations. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995 provides a "safe harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
" for such forward-looking statements. In order to comply with the terms of the safe harbor, Applera Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. These factors include but are not limited to (1) rapidly changing technology could adversely affect demand for Applied Biosystems' products, and its business is dependent on development and customer acceptance of new products; (2) Applied Biosystems' sales are dependent on customers' capital spending capital spending

Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years.
 policies and government-sponsored research; (3) potential liabilities related to the risk that the detection kits will not detect the organism they are intended to detect, or that they may incorrectly yield a positive result when the organism is not present in the sample tested; (4) risks associated with lawsuits, arbitrations, investigations, and other legal actions with private parties and governmental entities, particularly involving claims for infringement of patents and other intellectual property rights, and the possibility that Applied Biosystems may need to license intellectual property from third parties to avoid or settle such claims; and (5) other factors that might be described from time to time in Applera Corporation's filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and Applera does not undertake any duty to update this information, including any forward-looking statements, unless required by law.

Copyright(C) 2006. Applera Corporation. All rights reserved. Applied Biosystems and Celera are registered trademarks, Applera, and Celera Genomics are trademarks of Applera Corporation or its subsidiaries in the U.S. and/or certain other countries.

TaqMan is a registered trademark of Roche Molecular Systems, Inc.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Geographic Code:1USA
Date:Mar 13, 2006
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