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Applied Biosystems/MDS Analytical Technologies Launch New Test Methods to Simplify Mass Spectrometry Applications.


New iMethods enhance food and environmental testing, forensic toxicology and clinical research

CARLSBAD, Calif. -- Applied Biosystems, a division of Life Technologies (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
:LIFE), and its mass spectrometry mass spectrometry
 or mass spectroscopy

Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields.
 joint-venture partner, MDS MDS,
n See temporomandibular pain-dysfunction syndrome.

MDS 1 Maternal deprivation syndrome, see there 2 Myelodysplastic syndrome, see there
 Analytical Technologies, a business unit of MDS Inc. (TSX TSX Toronto Stock Exchange (TSE before April, 2002)
TSX Transfer from Stack Pointer to Index
TSX True Space Extension
:MDS)(NYSE NYSE

See: New York Stock Exchange
:MDZ MDZ Mendez
MDZ Moskauer Deutsche Zeitung (Moscow German newspaper)
MDZ Maritime Defense Zone
MDZ Musik Der Zukunft (music label & community)
MDZ Mendoza, Mendoza, Argentina - El Plumerillo
), today announced the commercial availability of a new suite of test methods that simplify the use of mass spectrometry technology for food and water quality testing, forensic toxicology and clinical research. The iMethod Tests consist of 23 pre-configured and verified workflows that can be downloaded and shared by laboratories to conduct scientific analysis on mass spectrometry instruments.

The new iMethods are enabled by the latest release of Applied Biosystems/MDS Analytical Technologies' chemical testing application, Cliquid([R]) 2.0 Software for Routine Screening and Quantitation, which enables analysis of compounds and contaminants on its triple quadrupole A quadrupole is one of a sequence of configurations of electric charge or gravitational mass that can exist in ideal form, but it is usually just part of a multipole expansion of a more complex structure reflecting various orders of complexity.  and QTRAP([R]) systems. These tests can be used for accelerating responses to contamination in drinking water drinking water

supply of water available to animals for drinking supplied via nipples, in troughs, dams, ponds and larger natural water sources; an insufficient supply leads to dehydration; it can be the source of infection, e.g. leptospirosis, salmonellosis, or of poisoning, e.g.
, protecting the food supply, as well as aiding clinical research to improve drug and metabolic disease metabolic disease,
n a disorder that causes dysfunction of the metabolic action of the body, resulting in loss of control of homeostasis.

paraneoplastic syndrome 
 monitoring. The iMethods were developed according to regulatory requirements, enabling laboratories to adopt them and eliminate the cost and complexity involved in building their own custom tests.

Among the organizations already using iMethods is the University of Guelph The University of Guelph is a medium-sized university located in Guelph, Ontario, established in 1964. While the U of G offers degrees in many different disciplines, the university is best known for its focus on life sciences, based in part on a long-standing history of  in Canada where food testing experts were planning to develop a test for carbamate carbamate /car·ba·mate/ (kahr´bah-mat) any ester of carbamic acid.

car·ba·mate
n.
A salt or ester of carbamic acid.
 pesticides, based on liquid chromatography tandem mass spectrometry Tandem mass spectrometry, also known as MS/MS, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages.  (LC/MS/MS). Instead, they decided to use the iMethod Test for this particular class of contaminant contaminant /con·tam·i·nant/ (kon-tam´in-int) something that causes contamination.

contaminant

something that causes contamination.
, due to the fact that it had already been verified and is readily available from the Applied Biosystems web site.

"The ready availability of test methods saves our laboratory the cost of developing and verifying tests that have already been adopted by other laboratories with specialized expertise," said Perry Martos, Director of the food testing laboratory at the University of Guelph. "The iMethod Tests enable us to quickly obtain answers with great confidence in the data we generate."

In addition to the carbamate pesticide method, other iMethods include testing for illicit drugs, pharmaceutical residues, immunosuppressants immunosuppressants,
n.pl the agents that lower or reduce immune response; useful in organ transplant surgery to prevent organ rejection. Corticosteroid hormones given in large amounts; cytotoxic drugs, including antimetabolites and alkylating agents;
 and vitamin D vitamin D

Any of a group of fat-soluble alcohols important in calcium metabolism in animals to form strong bones and teeth and prevent rickets and osteoporosis. It is formed by ultraviolet radiation (sunlight) of sterols (see steroid) present in the skin.
, among others. The iMethods Tests and Cliquid 2.0 Software are part of a workflow solution supported by Applied Biosystems/MDS Analytical Technologies' LC/MS/MS mass spectrometry systems.

"Mass spectrometry is increasingly being used for a wide variety of applications," said Laura Lauman, President of Life Technologies' Mass Spectrometry Systems Division. "Applied Biosystems and MDS Analytical Technologies continue to innovate in developing complete workflow solutions that deliver the most accurate and reproducible data, providing our customers with confidence in their results."

Andy Boorn, President of MDS Analytical Technologies, which developed the mass spectrometry technology for iMethod Tests, added, "The new iMethods and the latest release of Cliquid software are examples of how our research and development pipeline is delivering differentiated, new products on a continuous basis across systems, software and a broad range of applications."

Applied Biosystems is a global leader in providing innovative instrument systems to accelerate academic and clinical research, drug discovery and development, pathogen detection and forensic DNA analysis DNA analysis Any technique used to analyze genes and DNA. See Chromosome walking, DNA fingerprinting, Footprinting, In situ hybridization, Jeffries' probe, Jumping libraries, PCR, RFLP analysis, Southern blot hybridization. . Applied Biosystems is a leading provider of mass spectrometry solutions through its joint venture with MDS Analytical Technologies. Applied Biosystems, along with Invitrogen - a leading provider of platform independent, essential life science technologies for disease and drug research, bioproduction and diagnostics - is part of Life Technologies. Applied Biosystems and Invitrogen products are used in nearly every major laboratory in the world.

For more information, please visit: www.appliedbiosystems.com and www.invitrogen.com.

About Life Technologies

Life Technologies Corporation (NASDAQ:LIFE) is a global biotechnology tools company dedicated to improving the human condition. Our systems, consumables and services enable researchers to accelerate scientific exploration, driving to discoveries and developments that make life even better. Life Technologies customers do their work across the biological spectrum, working to advance personalized medicine, regenerative science, molecular diagnostics, agricultural and environmental research, and 21st century forensics. Life Technologies had sales of more than $3 billion in 2008, employs approximately 9,500 people, has a presence in more than 100 countries, and possesses a rapidly growing intellectual property estate of approximately 3,600 patents and exclusive licenses. Life Technologies was created by the combination of Invitrogen Corporation and Applied Biosystems Inc. For more information on how we are making a difference please visit our website: www.lifetechnologies.com.

About MDS Analytical Technologies

MDS Analytical Technologies, a business unit of MDS Inc. (TSX: MDS; NYSE: MDZ), is focused on the research, design, manufacture and marketing of state-of-the-art tools for mass-spectrometry, drug discovery and bioresearch bi·o·re·search  
n.
Research in the biological sciences.
. MDS Analytical Technologies' products are designed to help accelerate the complex process of discovering and developing new drug compounds, and are sold to research scientists around the world. The mass-spectrometer product lines are also sold globally through joint ventures with two of the world's leading analytical instrumentation and life-sciences companies, Life Technologies Corporation and PerkinElmer, Inc. Find out more at www.mdssciex.com or www.moleculardevices.com.

Life Technologies' Safe Harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
 Statement

This press release includes forward-looking statements about our anticipated results that involve risks and uncertainties. Some of the information contained in this press release, including, but not limited to, statements as to industry trends and Life Technologies' plans, objectives, expectations and strategy for its business, contains forward-looking statements that are subject to risks and uncertainties that could cause actual results or events to differ materially from those expressed or implied by such forward-looking statements. Any statements that are not statements of historical fact are forward-looking statements. When used, the words "believe," "plan," "intend," "anticipate," "target," "estimate," "expect" and the like, and/or future tense or conditional constructions ("will," "may," "could," "should," etc.), or similar expressions, identify certain of these forward-looking statements. Important factors which could cause actual results to differ materially from those in the forward-looking statements are detailed in filings made by Life Technologies with the Securities and Exchange Commission. Life Technologies undertakes no obligation to update or revise any such forward-looking statements to reflect subsequent events or circumstances.

Copyright 2009. Life Technologies Corporation. All rights reserved. Cliquid is a registered trademark of Applied Biosystems/MDS Analytical Technologies, a joint venture between Life Technologies and MDS Inc.
COPYRIGHT 2009 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2009 Gale, Cengage Learning. All rights reserved.

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Publication:Business Wire
Date:Mar 10, 2009
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