Apoptosis and cancer; methods and protocols.9781588294579 Apoptosis apoptosis or programmed cell death Mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. It may be initiated when a cell is no longer needed, when a cell becomes a threat to the organism's health, or for other reasons. and cancer; methods and protocols. Ed. by Gil Mor and Ayesha B. Alvero. Humana Press Inc. 2008 266 pages $99.50 Hardcover Methods in molecular biology molecular biology, scientific study of the molecular basis of life processes, including cellular respiration, excretion, and reproduction. The term molecular biology was coined in 1938 by Warren Weaver, then director of the natural sciences program at the Rockefeller ; 414 RC268 The failure of apoptosis--programmed cell death--has long been implicated im·pli·cate tr.v. im·pli·cat·ed, im·pli·cat·ing, im·pli·cates 1. To involve or connect intimately or incriminatingly: evidence that implicates others in the plot. 2. in the onset of cancer, but recently it has also been associated more specifically with the acquisition of resistance to chemotherapy and immune effectors. Biological scientists, many describing instruments made by the companies they work for, detail contemporary techniques for studying the biology of apoptosis and its role in cancer and resistance. Among the aspects they discuss are the modulation modulation, in communications modulation, in communications, process in which some characteristic of a wave (the carrier wave) is made to vary in accordance with an information-bearing signal wave (the modulating wave); demodulation is the process by which of apoptosis to reverse chemo-resistance, assessing the expression of apoptotic markers using large cohort tissue microarrays Tissue microarrays (also TMAs) consist of paraffin blocks in which up to 1000 separate tissue cores are assembled in array fashion to allow simultaneous histological analysis. , and caspase activity assays. ([c]20082005 Book News, Inc., Portland, OR) |
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