Aperio Partners With HistoRx to Provide Integrated Fluorescence Whole Slide Imaging System.Fluorescence Scanner and Image Analysis Software Offer Complete Solution for Biomarker Discovery Biomarker discovery is the process by which biomarkers are discovered. It is a medical term. Many commonly used blood tests in medicine are biomarkers. The way that these tests have been found can be seen as biomarker discovery. VISTA, Calif. & NEW HAVEN New Haven, city (1990 pop. 130,474), New Haven co., S Conn., a port of entry where the Quinnipiac and other small rivers enter Long Island Sound; inc. 1784. Firearms and ammunition, clocks and watches, tools, rubber and paper products, and textiles are among the many , Conn. -- Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, and HistoRx, Inc., (HistoRx), a leader in the emerging field of tissue-based assays for targeted patient treatment, have entered into a partnership to provide an integrated solution for whole-slide imaging with fluorescence. The partnership integrates Aperio's new ScanScope[R] FL, a multi-slide fluorescence scanning system designed to meet the growing demand for multiplexing with fluorescent biomarkers and quantitative analysis Quantitative Analysis A security analysis that uses financial information derived from company annual reports and income statements to evaluate an investment decision. Notes: , with HistoRx' AQUA[R] (Automated Quantitative Analysis) software for fluorescent image analysis that provides in-depth scientific insights from biomarker measurements. Aperio will be a value-added reseller A value-added reseller (VAR) is a company that adds some feature(s) to an existing product(s), then resells it (usually to end-users) as an integrated product or complete "turn-key" solution. of the AQUA software. Aperio CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. Dirk G. Soenksen said, "With HistoRx, we see an opportunity to meet the growing trend in scientific research and drug discovery toward the use of fluorochrome-labeled tissue markers for diagnosis, treatment selection and monitoring in cancer." HistoRx' AQUA image analysis technology can be used for quantitative assessment of protein expression in fixed tissue by measuring the intensity of expression in a particular cellular compartment Cellular compartments in cell biology comprise all closed parts within a cell whose lumen is usually surrounded by a single or double lipid layer membrane. Most organelles are compartments like mitochondria, chloroplasts (in photosynthetic organisms), peroxisomes, lysosomes, the , such as the cytoplasmic cytoplasmic pertaining to or included in cytoplasm. cytoplasmic inclusions include secretory inclusions (enzymes, acids, proteins, mucosubstances), nutritive inclusions (glycogen, lipids), pigment granules (melanin, lipofuscin, or nuclear compartment. The output of the analysis, called the AQUA score, can be correlated with other parameters such as disease detection, progression, response to therapy, or expression of proteins in alternate pathways. This technology will help to advance personalized medicine by identifying and validating new drug targets. The AQUA analysis application will interface with Aperio's Spectrum Plus[TM] image and data management platform, giving customers a seamless experience digitizing, viewing and analyzing fluorescence slides. "Partnering with the global leader in digital pathology is a significant expansion of the availability of HistoRx AQUA technology," said Rana K. Gupta, CEO of HistoRx. "We are pleased to collaborate with Aperio in helping pathologists worldwide improve their ability to identify correlations between biomarker expression and patient response to therapy." About HistoRx HistoRx, Inc. is a leading developer of tissue-based theranostic solutions to advance individualized in·di·vid·u·al·ize tr.v. in·di·vid·u·al·ized, in·di·vid·u·al·iz·ing, in·di·vid·u·al·iz·es 1. To give individuality to. 2. To consider or treat individually; particularize. 3. patient care. The company's products and services are based on proprietary AQUA[R] technology for tissue biomarker analysis. AQUA[R] software is the only platform capable of precisely measuring protein biomarker concentration with subcellular sub·cel·lu·lar adj. 1. Situated or occurring within a cell: subcellular organelles. 2. Smaller in size than ordinary cells: subcellular organisms. 3. resolution in tissue sections, enabling fully objective, standardized, reproducible, and automated analysis to guide targeted drug development and therapeutic decision making. HistoRx currently helps biopharmaceutical companies advance their product pipelines by generating valuable new insights into the safety and effectiveness of targeted therapeutics in development for cancer and other diseases, and is developing clinical assays based on these insights. About Aperio Aperio is the leading provider of digital pathology solutions in hospital and reference labs, academic medical centers, and biopharma institutions across the world. Today, our affordable and complete product portfolio is proven to lower costs, increase efficiencies, and enhance workflow in labs everywhere. Our comprehensive product line features our ScanScope[R] scanners, Spectrum[TM] image management (PACS (Picture ArChiving System) A storage and management system for high-resolution images. Typically pertaining to the medical field, images such as X-rays, MRIs and CAT scans require a greater amount of storage than other industries. ) software, SecondSlide[TM] slide sharing service for pathology, and image analysis tools and services. Aperio's products are FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. cleared for specific clinical applications, and are intended for research and education use for other applications. For clearance updates and more information please visit www.aperio.com. |
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