Antidepressant drugs banned for children.The UK Medicines and Healthcare Products Regulatory Agency The Medicines and Healthcare products Regulatory Agency (MHRA) is the UK government agency which is responsible for ensuring that medicines and medical devices work and are acceptably safe. (MHRA) has told doctors not to prescribe all but one (Prozac) of the selective serotonin reuptake inhibitor selective serotonin reuptake inhibitor n. SSRI. Selective serotonin reuptake inhibitor (SSRI) A class of antidepressants that work by blocking the reabsorption of serotonin in the brain, raising the levels of (SSRI SSRI selective serotonin reuptake inhibitor. SSRI n. Selective serotonin reuptake inhibitor; a class of drugs that inhibit the reuptake of serotonin in the central nervous system, used to treat depression and other ) antidepressants to children. This follows evidence from clinical trials carried out in the late 1990s, that had subsequently been suppressed, that they can cause children to become suicidal. Trials that did not produce favourable results were neither published nor sent to the FDA (US) or the MHRA. In fact trials into one of the drugs, Lustral Lustral® Sertraline, see there (manufactured by Pfizer), found that 9% of children using it became suicidal. It is thought that as many as 50,000 children are on antidepressants in Britain. With Prozac only being effective in around 10% of children, and with a significant shortage of trained counsellors and psychotherapists available, severe problems lie ahead. (The Guardian, December 10, 2003). |
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