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Antibiotic-eating germ alarms doctors.


For 50 years, doctors have been assailing bacteria with the best antimicrobials science can devise, but the bugs have shown a remarkable ability to adapt to the onslaught. Bacteria not only survive, they thrive. Worse, they continue to feast on people, which is why doctors are so concerned about antibiotic-resistant microbes.

Now, researchers at St. George's Noun 1. St. George's - the capital and largest city of Grenada
capital of Grenada

Grenada - an island state in the West Indies in the southeastern Caribbean Sea; an independent state within the British Commonwealth
 Hospital Medical School in London say they have isolated a bacterium from two patients that is not only resistant to an antibiotic but actually dependent upon it. This bacterium, a strain of Enterococcus faecium Enterococcus faecium A nosocomial pathogen resistant to most antibiotics–eg, penicillin, teicoplanin, aminoglycosides, glycopeptides; ID of E faecium in a clinical specimen requires Pt isolation with barrier precautions. , cannot survive without a steady diet of vancomycin vancomycin (văn'kōmī`sĭn), antibiotic resembling penicillin in the way it acts. It is derived from the bacterium Streptomyces orientalis, which was isolated from soil of India and Indonesia. , report Nadia Farrag, Ian Eltringham, and Helen Liddy in the Dec. 7 Lancet. This finding suprised the researchers because vancomycin is one of the most potent antibiotics known.

The two patients were men in their sixties. One had a ruptured esophagus that required emergency treatment, and the other had undergone prostate cancer prostate cancer, cancer originating in the prostate gland. Prostate cancer is the leading malignancy in men in the United States and is second only to lung cancer as a cause of cancer death in men.  surgery. Both developed Enterococcus enterococcus /en·tero·coc·cus/ (en?ter-o-kok´us) pl. enterococ´ci   an organism belonging to the genus Enterococcus.
Enterococcus /En·tero·coc·cus/ (
 infections and were treated with vancomycin. The antibiotic initially seemed to banish the infection, but the bugs bounced back. When researchers began testing the germs, they found the vancomycin-dependent strains, which alarmed them. "Have we at last witnessed the emergence of a true superbug su·per·bug
n.
Any of various disease-causing bacteria that develop a resistance to drugs normally used to control or eradicate them.



superbug
?" the trio asked, tabloid-style, in Lancet.

Mark Wilks, a microbiologist at St. Bartholomew's Hospital Medical College in London, blames this "rhetorical flourish" for "elevating an interesting laboratory phenomenon to the status of yet another health panic."
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Copyright 1996, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Title Annotation:Biomedicine; Enterococcus faecium bacterium survives on diet of the antibiotic vancomycin
Publication:Science News
Article Type:Brief Article
Date:Dec 21, 1996
Words:234
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