AntiCancer Inc. develops first in vivo cancer therapeutic gene screen, a major step in speeding development of cancer gene therapy.SAN DIEGO--(BUSINESS WIRE)--Nov. 17, 1994--AntiCancer Inc. Thursday announced the first patient-like animal model of human cancer that can be used to discover, evaluate and develop genes for cancer therapy. Dr. Andrew Perry of AntiCancer said: ``We feel this gene discovery model is a tremendous breakthrough. Up until now, gene therapy has suffered from the lack of an animal model to reliably evaluate effectiveness of this cancer therapy. Our new animal model will be a major cost savings to anyone involved in gene-therapy research and should lead to faster development of new treatments for cancer.'' AntiCancer calls this new model MetaMouse. The model uses special immune-deficient mice transplanted with human tumors to replicate the metastatic Metastatic The term used to describe a secondary cancer, or one that has spread from one area of the body to another. Mentioned in: Coagulation Disorders metastatic pertaining to or of the nature of a metastasis. behavior of the tumor tumor: see neoplasm. in the patient. The model is being presented this week in conjunction with the San Diego San Diego (săn dēā`gō), city (1990 pop. 1,110,549), seat of San Diego co., S Calif., on San Diego Bay; inc. 1850. San Diego includes the unincorporated communities of La Jolla and Spring Valley. Coronado is across the bay. ``Genetic Revolution'' conference. ``MetaMouse models have been developed for all the major human cancers. MetaMouse puts cancer gene-therapy discovery and development on a rational basis. With the MetaMouse models for each cancer type, candidate cancer therapeutic genes can be tested against the primary tumor primary tumor A neoplasm which, in clinical parlance, is regarded as malignant, arising in one site and capable of giving rise to metastatic or secondary tumors. See Metastasis. Cf Tumor of unknown origin. and, more importantly, the killer metastases Metastasis (plural, metastases) A tumor growth or deposit that has spread via lymph or blood to an area of the body remote from the primary tumor. Mentioned in: Malignant Melanoma . Different routes of delivery can be assessed such as arterial delivery directly to liver metastases. Different types of carriers such as liposomes Liposomes Aqueous compartments enclosed by lipid bilayer membranes; liposomes are also known as lipid vesicles. Phospholipid molecules consist of an elongated nonpolar (hydrophobic) structure with a polar (hydrophilic) structure at one end. can also be assessed directly,'' said Perry. ``The MetaMouse models should help to rush promising cancer therapeutic genes to the clinic.'' AntiCancer is a privately held biotechnology company located in San Diego. The company was founded in 1984 specifically to work in the field of cancer treatment and is developing a range of cancer therapeutics and diagnostics. CONTACT: AntiCancer Inc., San Diego Andrew Perry, 619/654-2555 |
|
||||||||||||||
Printer friendly
Cite/link
Email
Feedback
Reader Opinion