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Antares Pharma Signs EasyTec(TM) ODT Agreement.


Provides Opportunity for Product Life Cycle Planning

EWING, N.J. -- Antares Pharma, Inc. (Amex:AIS) announced the signing of a feasibility and development agreement with an unnamed multi-national pharmaceutical partner for an opioid analgesic analgesic (ăn'əljē`zĭk), any of a diverse group of drugs used to relieve pain. Analgesic drugs include the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, narcotic drugs such as morphine, and synthetic drugs  to be delivered using Antares' proprietary EasyTec[TM] oral disintegrating tablet (ODT See SCO Open Desktop.

ODT - Open Desktop
) delivery platform. EasyTec (ODT) tablets disintegrate in approximately 10 to 30 seconds with only saliva and may assist in patient compliance. EasyTec (ODT) importantly also provides an opportunity for product life cycle planning and is patented in both the U.S. and Europe. Antares will receive funding for both feasability and development activities over the course of the contract. It is anticipated that the parties will enter into an exclusive licensing arrangement upon satisfactory evaluation.

Jack E. Stover, President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Antares Pharma, said, "This agreement represents an important milestone in potentially validating the utility of Antares' proprietary EasyTec (ODT) technology, as a component of life cycle planning for opiates Opiates
Analgesic, pain killing drugs, such as heroin and morphine that depress the central nervous system.

Mentioned in: Withdrawal Syndromes
."

About EasyTec[TM] Orally Disintegrating Tablet The Food and Drug Administration's (FDA) definition of an orally disintegrating tablet (ODT) is: "A solid dosage form containing medicinal substances which disintegrates rapidly, usually within a matter of seconds, when placed upon the tongue.  (ODT) Fast-Dissolve Technology

Antares Pharma's EasyTec[TM] is a simple, cost-efficient, and robust technology platform which uses direct compression during the tablet making process. EasyTec[TM] relies on the combination of classic disintegrants and a specific excipient excipient /ex·cip·i·ent/ (ek-sip´e-int) any more or less inert substance added to a drug to give suitable consistency or form to the drug; a vehicle.

ex·cip·i·ent
n.
 to enhance rates of disintegration. All excipients excipients,
n.pl all the constituents of a remedy that lack medicinal properties. See also adjuvant, auxiliary substance, and vehicle.
 are compendial, low cost, and do not involve special production or manufacturing equipment. EasyTec[TM] tablets satisfy pharmacopoeial requirements for hardness and friability fri·a·ble  
adj.
Readily crumbled; brittle: friable asbestos insulation.



[Latin fri
 when compared to conventional tablets, therefore conventional high-speed rotary tablet presses are used for tablet compression and there is no requirement for specialized packaging. The disintegration time is generally less than 10 seconds for EasyTec tablets with a mass lower than 200 mg increasing up to 30 seconds for tablets with a mass increasing to 1000 mg. EasyTec[TM] technology is compatible with a broad range of actives, with high or low drug loading, and can be used with traditional and specialized excipient categories in addition to the incorporation of taste-masking and flavouring technologies.

Antares Pharma

Antares Pharma is a specialized pharma product development company focused on developing patented drug delivery systems and injectable device engineering capabilities. Antares' current technology platforms include its ATD ATD Anthropomorphic Test Dummy
ATD Attention to Detail
ATD Advanced Technology Demonstration
AtD Achieving the Dream
ATD Atmospheric Technology Division (US National Center for Atmospheric Research)
ATD Assistant Technical Director
[TM] Advanced Transdermal Delivery system transdermal delivery system: see skin patch. , and its related TecTix[TM] system for topical and transmucosal delivery, its Easy Tec[TM] oral fast-melt technology, and subcutaneous injection technology platforms including both Vibex[TM] disposable mini-needle injection device and Valeo[TM]/Vision[R] reusable needle-free injection devices. Antares Pharma is committed to leveraging its multiple drug delivery platforms to add value to existing drugs and to create new pharmaceutical products and injectable devices. Overall, Antares' product pipeline, if approved, will address unmet medical needs by reducing side effect profiles, improving safety, increasing effectiveness, and improving patient compliance and convenience. Antares Pharma has corporate headquarters in Princeton Crossroads Corporate Center in Ewing, NJ, with subsidiaries performing research, development, manufacturing and product commercialization activities in Minneapolis, Minnesota and Basel, Switzerland.

Safe Harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
 Statement

In addition to historical facts or statements or current conditions, this press release contains forward-looking statements within the meaning of the "Safe Harbor" provisions of The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995, including statements regarding the timing of product sales, market estimates and market potential. Forward-looking statements provide Antares' current expectation or forecasts of future events. Antares' results could differ materially from those reflected in these forward-looking statements due to decisions of regulatory authorities, Antares' ability to execute on its development plans and general financial, economic, regulatory and political conditions affecting the pharmaceutical industry generally. For a discussion of these and other risks and uncertainties that may effect the forward-looking statements, please see the risk factors in Antares' quarterly reports filed with the Securities and Exchange Commission. Given these risks and uncertainties, any or all of these forward-looking statements may prove to be incorrect. Antares undertakes no obligation to update publicly any forward-looking statement.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Nov 28, 2006
Words:638
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