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Anorexia impairs bone development in teens, shows study.


Byline: ANI

Washington, Nov 18 (ANI): With the help of a new CT technology, researchers have found that children and teenagers with even mild cases of anorexia exhibit abnormal bone structure.

Anorexia is an eating disorder characterized by emaciation, distorted body image and intense fear of gaining weight. People with the disorder are obsessed with weight control and often perceive themselves as overweight, even when they are dangerously thin.

"Adolescence is the most critical period for growth of bone mass, and the onset of anorexia interferes with that process," said Miriam A. Bredella, M.D., musculoskeletal radiologist at Massachusetts General Hospital and assistant professor of radiology at Harvard Medical School Harvard Medical School (HMS) is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  in Boston.

"Impairment of bone development may permanently alter bone structure and increase the risk of fractures and osteoporosis in adult life," she added.

Traditionally, dual energy x-ray absorptiometry Dual energy X-ray absorptiometry (DXA, previously DEXA) is a means of measuring bone mineral density (BMD). Two X-ray beams with differing energy levels are aimed at the patient's bones.  (DXA DXA Dual Energy X-Ray Absorptiometry (radiology)
DXA Direct Exchange Activity
) is used to test bone mineral density bone mineral density
n.
See bone density.


bone mineral density A measurement of bone mass, expressed as the amount of mineral–in grams divided by the area scanned in cm2. See Bone densitometry.
 in adolescents with anorexia.

Dr. Bredella and colleagues set out to determine if alterations in bone structure occur before significant decreases in bone mineral density become evident.

In the study involving 10 adolescent girls, age 13 to 18, the researchers used high-resolution, flat-panel volume computed tomography (CT) and DXA

The new, high-resolution CT exam allowed the researchers to identify differences in bone structure between the patients with anorexia and the healthy controls, whereas bone mineral density measurements obtained using DXA did not.

"Our data suggest that reassuring values of bone mineral density obtained using DXA may not reflect the true status of bone structure in this undernourished population," said Bredella.

"In patients with anorexia, bone structure should be analyzed to detect abnormal bone health.

"Flat-panel volume CT allows the examination of bone at high resolution with relatively low radiation exposure making it a suitable technique for evaluation of bone structure in adolescent patients," she added. (ANI)

Copyright 2008 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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Publication:Asian News International
Date:Nov 25, 2008
Words:320
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