Announcing Centeon, the largest worldwide plasma protein therapies company; Millions of patients to benefit from significant R & D investment and future innovation.NEW YORK--(BUSINESS WIRE)--Jan. 10, 1996--In a move to create the first global plasma protein plasma protein n. Any of the various dissolved proteins of blood plasma, including antibodies and blood-clotting proteins, that act by holding fluid in blood vessels by osmosis. therapies company, Hoechst AG and Rhone-Poulenc Rorer Inc. (NYSE NYSE See: New York Stock Exchange : RPR (Resilient Packet Ring) A packet-based protocol that provides fault tolerance and statistical multiplexing for the metropolitan and national SONET and Ethernet networks of the carriers. ) are announcing the formation of Centeon, a 50/50 joint venture between Hoechst and Rhone-Poulenc Rorer. Centeon now becomes the leader in the global plasma therapeutics field. To create this new $1.2 billion company, Hoechst has contributed all of the assets of the plasma protein division of Behringwerke AG, a Hoechst subsidiary based in Germany, and Rhone-Poulenc Rorer (RPR) has contributed all of the plasma protein-related assets of its subsidiary, Armour Pharmaceutical Company, based in the United States. "Our strategy is clear: Centeon will invest in research and development to lead the plasma protein industry in accelerating the availability of new products from human plasma and through biotechnology," said John A. Sedor, CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Centeon, headquartered in King of Prussia, Pennsylvania For Kings of Prussia, see List of rulers of Prussia King of Prussia is an unincorporated community in Upper Merion Township, Montgomery County, Pennsylvania, United States. As of the 2000 census, its population was 18,511. . "In an industry typified by regionalized companies, Centeon will have the critical mass and market access to meet patients' needs worldwide." "We are pleased to have created the world's leading plasma protein company," said Dr. Karl-Gerhard Seifert, Chairman of the Board of Centeon and a member of the Board of Management of Hoechst AG. "Centeon represents another significant accomplishment for Hoechst in meeting its commitment to expand the company's presence in the U.S. marketplace." Added Michel de Rosen Michel de Rosen (born 1951-02-18) is Chief Executive Officer and Chairman of the Board of Directors of ViroPharma Incorporated (since 2002-08-22), President and Chief Executive Officer (since August 2000), and Director (since May 2000. , a member of the Board of Centeon and President and CEO, Rhone-Poulenc Rorer Inc., "The launch of this new company fulfills Rhone-Poulenc Rorer's stated objective to become a leader in the plasma protein area, and the joint venture achieves this goal." Plasma protein products are used in such therapeutic categories as immune deficiencies, trauma, coagulation disorders Coagulation Disorders Definition Coagulation disorders deal with disruption of the body's ability to control blood clotting. The most commonly known coagulation disorder is hemophilia, a condition in which patients bleed for long periods of time before , bone marrow transplants and neurologic disorders. Centeon provides a comprehensive range of plasma products in all of the therapeutic applications. These include antihemophilic factors, immunoglobulins, plasma substitutes, wound healing wound healing Physiology The repair of a wound Steps Inflammation, repair and closure, remodeling, final healing; repair of incisions may be either simple–'clean' wounds with little loss of tissue heal by 'primary intention', or 'dirty' wounds heal by agents and inhibitor treatments. "Millions of people around the globe require plasma products. Through our increased investment in plasma protein and biotechnology research, Centeon will now have a greater capacity for innovation than Armour and Behring could separately," said Sedor. Centeon's Strategic Vision Centeon is focused on three critical areas: increasing R & D investment, better utilizing plasma resources, and ensuring high purity and viral safety for the company's plasma products. Research and Development Investment Centeon will invest in R & D at twice the current level of Armour and Behring combined, greatly enhancing the company's potential to achieve scientific breakthroughs and develop new life-saving therapies to satisfy unmet medical needs. Armour and Behring's complementary R & D strengths will allow Centeon to focus on a number of new research frontiers including: -0- -- Blood components: Investigating modified blood components, including red blood cells Red blood cells Cells that carry hemoglobin (the molecule that transports oxygen) and help remove wastes from tissues throughout the body. Mentioned in: Bone Marrow Transplantation red blood cells and lyophilized ly·oph·i·lize tr.v. ly·oph·i·lized, ly·oph·i·liz·ing, ly·oph·i·liz·es To freeze-dry (blood plasma or other biological substances). [lyophil(ic) + -ize. platelets, for use in transfusion medicine transfusion medicine Blood banking A subspecialty of clinical pathology or internal medicine which is involved in Pt management through administration of blood cells and blood products including fresh-frozen plasma and cryoprecipitate; TM specialists are versant in . -- rDNA technology: Developing therapeutics prepared by recombinant technology that improves the treatment of hemophilia. -- Gene therapy: Repairing genetic defects, replacing missing genes, and using non-plasma therapies are some of the most exciting frontiers in the treatment of genetic diseases. -0- Plasma Resources Plasma is in limited supply worldwide. By combining the complementary product lines of Armour and Behring and the best technology from both companies, Centeon will be positioned to use existing plasma resources more efficiently. Centeon will optimize plasma usage by increasing the number of products derived from a single liter of plasma. Commitment to Safety Critical to the processing and production of plasma protein therapies is the issue of safety. Both Armour and Behring have pioneered innovative plasma purification and viral inactivation inactivation /in·ac·ti·va·tion/ (in-ak?ti-va´shun) the destruction of biological activity, as of a virus, by the action of heat or other agent. techniques. Centeon will provide viral safety by combining the largest and most sophisticated commercial plasma collection and tracking operation in the world, with advanced technology for viral inactivation and purification of products. In addition to complementary R&D strengths and product lines, Armour and Behring also complement each other geographically. Armour has a strong presence in the United States, while Behring is a leader in Europe and Japan. "Strategically, this was important to us. These three markets represent more than three-fourths of the plasma protein therapies industry," said Sedor. "Also, because of the complements between Armour and Behring, Centeon is maintaining all existing operations and plans to expand at the R&D and manufacturing levels." Centeon is a stand-alone company run by an independent management team with a Board of Directors. Centeon is headquartered in King of Prussia, Pennsylvania, with corporate functions in both the United States and Germany. The company will employ approximately 4,500 people worldwide and has plasma fractionation fractionation /frac·tion·a·tion/ (frak?shun-a´shun) 1. in radiology, division of the total dose of radiation into small doses administered at intervals. 2. plants in the United States in Kankakee, Illinois, and in the European cities of Marburg, Germany; Strasbourg, France; Vienna, Austria; and Barcelona, Spain. -0- Note to Editors: Photos FPS (Frames Per Second) The measurement of full-motion video performance. See frame. fps - frames per second one, two of January 10, have moved on AP Photo Express CONTACT: Ketchum Public Relations Kirsten Gorsuch, 212/878-4677 or Centeon Beth Leahy, 610/878-4152 |
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