Animal-based nutrients associated with greater risk of some types of cancer. (Scientific update: a review of recent scientific papers related to vegetarianism).A recent study examined dietary factors that could increase risk of developing cancer of the esophagus esophagus (ĭsŏf`əgəs), portion of the digestive tube that conducts food from the mouth to the stomach. When food is swallowed it passes from the pharynx into the esophagus, initiating rhythmic contractions (peristalsis) of the or stomach. Dietary factors may be important because both the esophagus and the stomach are exposed to the food we eat. Nearly 500 people with cancer of the esophagus, 600 people with stomach cancer, and almost 700 healthy people were studied. Each person was questioned about his or her eating habits three to five years earlier (before those with cancer had cancer). The groups were then compared. Those with cancer of the esophagus or stomach had higher intakes of cholesterol, animal protein, and vitamin [B.sub.12], suggesting that their diets were higher in animal products. Those without cancer had higher intakes of fiber, beta-carotene, and folate folate /fo·late/ (fo´lat) 1. the anionic form of folic acid. 2. more generally, any of a group of substances containing a form of pteroic acid conjugated with l-glutamic acid and having a variety of substitutions. , suggesting that their diets were higher in plant-based foods. These results are especially pertinent for people with gastroesophageal reflux disease gastroesophageal reflux disease (GERD) Disorder characterized by frequent passage of gastric contents from the stomach back into the esophagus. Symptoms of GERD may include heartburn, coughing, frequent clearing of the throat, and difficulty in swallowing. (also called reflux esophagitis reflux esophagitis n. Inflammation of the lower esophagus from regurgitation of acid gastric contents, characterized by substernal pain and usually due to malfunction of the lower esophageal sphincter. Also called peptic esophagitis. ), who are more likely to develop cancer of the esophagus. The results of this study suggest that diets rich in fruits, vegetables, and fiber, and low in animal protein and fat, could be especially useful for those with gastroesophageal reflux disease to reduce their risk of developing cancer of the esophagus. Mayne ST, Risch HA, et al. 2001. Nutrient intake and risk of subtypes of esophageal and gastric cancer gastric cancer Stomach cancer, see there . Cancer Epidemiol Biomarkers Prey 10:1055-1062. |
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