Anal cytology screening for lesions among HIV-positive patients.Anal carcinoma is relatively rare although its incidence is increasing, particularly among HIV-positive men who have sex with men Men who have sex with men (MSM) is a term used mostly in the United States to classify men who engage in sex with other men, regardless of whether they self-identify as gay, bisexual, or heterosexual. . Anal carcinoma shares many similarities with cervical cancer, and based on the cervical cancer screening programme, many experts have suggested that routine anal cytology cytology (sītŏl`əjē), in biology, the study of the structure of all normal and abnormal components of cells and the changes, movements, and transformations of such components. screening be performed on high-risk individuals to detect and remove pre-cancerous anal lesions. This study describes a routine anal cytology screening programme in an urban HIV-positive population in the US to determine risk factors for abnormal anal cytology and whether an association exists between abnormal cytology and histology.
49% of the 560 clinic patients were screened for two years, of whom 32% were women. 28% had abnormal anal cytology, and they were also more likely to have anal disease on perianal perianal
around the anus.
under the skin outside the anal canal. Causes sufficient pain to inhibit defecation. visual inspection and a history of genital warts. They were also more likely to be caucasian, homosexual or bisexual and have a lower CD4+ count. Routine anal cytology screening is a feasible tool to incorporate into routine HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States. care. Cytological abnormalities were found in patients without obvious risk factors, suggesting that all HIV-positive patients should have anal cancer screening. The follow-up for abnormal cytology represents the most difficult aspect of the programme, including getting patients to come for anoscopy. (1)
(1.) Scott H, Khoury R, Moore BA, et al. Routine anal cytology screening for anal squamous intraepithelial lesions in an urban HIV clinic. Sexually Transmitted Diseases 2008;35(2):197-202.