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An Essential Report on Diagnostic Imaging Agents - Discover the Next Generation of New Contrast Agents to Detect Metabolic Changes at the Molecular Level.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/research/735b4b/diagnostic_imaging) has announced the addition of the "Diagnostic Imaging Agents - The Next Generation" report to their offering.

Driven by advances in molecular probe design and biomarker detection methodologies, new imaging agents that can improve visualization of pathologies and cellular processes are changing the practice of diagnostic medicine. The ability of this new generation of contrast agents to detect metabolic changes at the molecular level has significant potential for improving visualization and quality of care. Targetable and activatable imaging agents are gaining interest for a wide range of diagnostic applications that include cardiology, neurology and soft tissue tumor detection. The number of healthcare conditions that can be effectively imaged noninvasivelyis expanding as a result of these innovative detection technologies. Targeted and activatable imaging agents offer a unique capability to generate unambiguous images by exploiting specific molecular targets, pathways or cellular processes. This new wave of imaging agents signals a paradigm shift A dramatic change in methodology or practice. It often refers to a major change in thinking and planning, which ultimately changes the way projects are implemented. For example, accessing applications and data from the Web instead of from local servers is a paradigm shift. See paradigm.  in which the reagents take on new importance alongside system hardware in revenue projections and product line ROI (Return On Investment) The monetary benefits derived from having spent money on developing or revising a system. In the IT world, there are more ways to compute ROI than Carter has liver pills (and for those of you who never heard of that expression, it means a lot). .

Imaging Processes at the Molecular and Cellular Level:

A number of challenging opportunities are on the horizon for medical imaging. Unlike many other sectors of the healthcare industry where technology successes periodical occur that seem to propel the market forward, these opportunities are being driven by the migratory migratory /mi·gra·to·ry/ (mi´grah-tor?e)
1. roving or wandering.

2. of, pertaining to, or characterized by migration; undergoing periodic migration.


migratory

emanating from or pertaining to migration.
 advances of academic, public (government) and commercial research programs.

The potential for the next generation of diagnostic imaging agents is significant. SPECT SPECT single-photon emission computed tomography.

SPECT
abbr.
single photon emission computed tomography


SPECT,
n See single photon emission computer tomography.
 and PET tracers Tracers

Refers to investment trusts which are populated by corporate bonds. In October 2001, Morgan Stanley's Tradable Custodial Receipts (Tracers) was launched. Tracers contain a number of coporate bonds and credit default swaps which are selected for liquidity and diversity.
 have been developed to measure oxidative metabolism, fatty acid fatty acid, any of the organic carboxylic acids present in fats and oils as esters of glycerol. Molecular weights of fatty acids vary over a wide range. The carbon skeleton of any fatty acid is unbranched. Some fatty acids are saturated, i.e.  and amino acid amino acid (əmē`nō), any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.  metabolism, and pre- and post-synaptic receptor densities. The ability of these first-generation agents to improve diagnostic and treatment capabilities is now driving a directed effort to develop the next-generation of molecular agents. To sense biological processes such as gene expression, angiogenesis angiogenesis /an·gio·gen·e·sis/ (-jen´e-sis) vasculogenesis; development of blood vessels either in the embryo or in the form of neovascularization or revascularization.

an·gi·o·gen·e·sis
n.
, apoptosis apoptosis
 or programmed cell death

Mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. It may be initiated when a cell is no longer needed, when a cell becomes a threat to the organism's health, or for other reasons.
 or cell trafficking in vivo in vivo /in vi·vo/ (ve´vo) [L.] within the living body.

in vi·vo
adj.
Within a living organism.



in vivo adv.
, imaging reporter agents that interact specifically with molecular targets and appropriate imaging systems are currently under development.

Molecular imaging will greatly reduce the need for animal tissue sampling or human biopsy when studying the progression of a disease or the follow-up of a gene therapy. It has the advantage of being non-invasive, and because it can be repeated many times, it provides both spatial and temporal dimensions to the understanding of the gene expression of the disease or therapy.

Market Data
The study presents qualitative and quantitative data and information
 on key market measures and benchmarks:
- Imaging Segment Assessment
- Commercial Limitations
- Global Market Analysis
- Company Profiles
- Technology Assessments
- Alliances and Strategies
- Commercialization Strategies
- Regulatory Factors
- Imaging Agent Development Criteria
- Technology Risk Factors
Key Topics Covered:
- Advanced Imaging Agents - Market Dynamics
- Diagnostic Imaging Technology
- Imaging Modalities & the Potential of Molecular Imaging
- The Need for New Imaging Agents
- Clinical Applications -Near-Term Assessment and Future Impact
- Market Factors
- Company Profiles


For more information visit http://www.researchandmarkets.com/research/735b4b/diagnostic_imaging
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Publication:Business Wire
Date:Oct 3, 2008
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