Amersham Biosciences Launches New Fully Automated High Throughput Multi-Step Protein Purification System.Business Editors/Health/Medical Writers BIOWIRE2K PISCATAWAY, N.J.--(BUSINESS WIRE)--March 8, 2004 AKTAxpress enables large quantities of high purity proteins to be produced on an industrialized in·dus·tri·al·ize v. in·dus·tri·al·ized, in·dus·tri·al·iz·ing, in·dus·tri·al·iz·es v.tr. 1. To develop industry in (a country or society, for example). 2. research scale The AKTA AKTA American Knife Throwers Alliance AKTA American Korean Taekwondo Association (TM)xpress, launched today by Amersham Biosciences, the life sciences business of Amersham (LSE LSE - Language Sensitive Editor :, NYSE NYSE See: New York Stock Exchange :, OSE OSE - Open Systems Environment : AHM AHM Automated Hacking Machines AHM All Hands Meeting AHM Academy for Healthcare Management AHM Atom Heart Mother (Pink Floyd album) AHM Airport Handling Manual AHM Acutely Hazardous Material AHM Anti-Helicopter Mine ), at Pittcon 2004, Chicago, Il, is the first fully integrated protein purification Protein purification is a series of processes intended to isolate a single type of protein from a complex mixture. Protein purification is vital for the characterisation of the function, structure and interactions of the protein of interest. system to deliver totally automated, high throughput, multi-step purification of His- and GST-tagged proteins. AKTAxpress is an invaluable tool for researchers working in structural genomics Noun 1. structural genomics - the branch of genomics that determines the three-dimensional structures of proteins genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences) where the determination of a protein's three-dimensional structure requires large quantities of extremely pure protein. AKTAxpress provides up to 50mg of proteins of the highest possible purity, maximising the chances of successful crystallisation. Furthermore, the high throughput provided by the system enables a large number of target proteins to be purified in a short time. AKTAxpress combines hardware, software and media in a truly automated way. No complex programming is required; the specifically designed UNICORN unicorn (y  `nĭkôrn), fabulous equine beast with a long horn jutting from the middle of its forehead. (TM) software wizard selects the optimum purification protocol, and automatically transfers the largest peak from every purification step to the next column. This multi-step process provides protein of greater than 95% purity. AKTAxpress accepts multiple samples to provide high throughput: researchers can purify eight proteins in one day using a four-step protocol, or 16 samples overnight using a two-step protocol. A standard system can be extended from four modules to twelve, so increasing throughput even further. The built-in knowledge of the AKTAxpress system means that high-purity proteins can be produced with great reproducibility, even by researchers inexperienced in protein purification. The entire process can run unattended, leaving operators' time free for other tasks. "The launch of AKTAxpress means that purifying tagged proteins will no longer be a bottle-neck in a researcher's workflow," says Allan Simpson, vice president, research and analysis marketing, at Amersham Biosciences. "The built-in knowledge of this fully integrated system means that our customers can obtain the high-purity proteins they need quickly, and easily. In fact, AKTAxpress is really a laboratory scale protein purification factory." Amersham Biosciences, the life sciences business of Amersham (LSE: NYSE: OSE: AHM), is a world leader in developing and providing integrated systems and solutions for disease research, drug development and manufacture. Our systems are used to uncover the function of genes and proteins, for the discovery and development of drugs and for the manufacture of biopharmaceuticals. The customers for Amersham Biosciences' products and technology are pharmaceutical and biotechnology companies and research and academic institutions, principally in North America, Europe, Latin America and Asia. More information about Amersham Biosciences is available at www.amershambiosciences.com Amersham Biosciences--enabling molecular medicine Protein separations - simpler protein purification |
|
||||||||||||
Printer friendly
Cite/link
Email
Feedback
Reader Opinion