Amersham Biosciences' Innovative ECL Advance Kit Offers 10-Fold Increased Sensitivity in Protein Detection.Business Editors/Health & Medical Writers BIOWIRE2K PISCATAWAY, N.J.--(BUSINESS WIRE)--Sept. 30, 2002 Chemiluminescent chem·i·lu·mi·nes·cence n. Emission of light as a result of a chemical reaction at environmental temperatures. chem Substrate for Western Blot Western blot A technique developed in 1979 that is used to confirm ELISA results. HIV antigen is purified by electrophoresis and attached by blotting to a nylon or nitrocellulose filter. Detection Yields Highest Sensitivity Amersham Biosciences, the life sciences business of Amersham plc (LSE LSE - Language Sensitive Editor : NYSE NYSE See: New York Stock Exchange : OSE OSE - Open Systems Environment : AHM AHM Automated Hacking Machines AHM All Hands Meeting AHM Academy for Healthcare Management AHM Atom Heart Mother (Pink Floyd album) AHM Airport Handling Manual AHM Acutely Hazardous Material AHM Anti-Helicopter Mine ), has introduced ECL (Emitter-Coupled Logic) A digital circuit composed of bipolar transistors in which the emitter ends are wired together. ECL gates switch faster than TTL gates, but consume more power. See TTL, I2L and bipolar. 1. (TM) Advance Western Blotting Detection Kit, containing the highest sensitivity chemiluminescent substrate available for the detection of immobilized protein. ECL Advance will enable scientists to visualize and identify proteins that previously went undetected due to their low concentrations. ECL Advance is up to 10 times more sensitive than other chemiluminescent Western blotting detection kits currently on the market. Added convenience and reliability are made possible by the inclusion of the innovative ECL Advance Blocking Agent blocking agent n. A drug that blocks transmission of nerve impulses at an autonomic receptor site, autonomic synapse, or neuromuscular junction. that controls backgrounds and ensures a high level of signal intensity. Antibody concentrations can also be reduced to previously unmatched levels allowing stocks of these potentially valuable preparations to be conserved. "Scientists now have an even more powerful solution for protein detection. With optimized reagents, ECL Advance offers both the highest sensitivity chemiluminescent Western blotting and the ability to reduce the concentration of antibody, thereby saving on the cost and supply of these valuable resources," says Pieter Noordeloos, VP Marketing, Proteomics, at Amersham Biosciences. "With its easy to follow protocols, the ECL Advance Western Blotting Detection Kit is particularly suitable for detecting low abundance proteins. It expands Amersham Biosciences' highly popular ECL product range, which has been the industry standard for chemiluminescent detection in Western blotting applications for more than 10 years." ECL Advance is a proprietary new substrate licensed exclusively to Amersham Biosciences by Lumigen, Inc. (Southfield, MI). It produces a much more intense light output than currently available substrates, which can be captured on film or by a CCD camera. Amersham Biosciences, the life sciences business of Amersham plc (LSE: NYSE: OSE: AHM), is a world leader in developing and providing integrated systems and solutions for disease research, drug development, and manufacture. Our systems are used to uncover the function of genes and proteins, for the discovery and development of drugs, and for the manufacture of biopharmaceuticals. The customers for Amersham Biosciences' products and technology are pharmaceutical and biotechnology companies and research and academic institutions, principally in North America, Europe, Latin America, and Asia. More information about Amersham Biosciences is available at www.amershambiosciences.com. Amersham Biosciences--enabling molecular medicine |
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