American Medical Systems' Her Option(R) Office Cryoablation Effectiveness to Be Presented at Upcoming AAGL Congress.

Important new findings will be shared on post-procedure quality-of-life, anesthesia and return to normal menstruation

MINNEAPOLIS -- American Medical Systems Holdings, Inc. (NASDAQ:AMMD) announced today that Her Option[R] Office Cryoablation will be supported by an unprecedented six (6) abstracts at the American Association of Gynecologic Laparoscopists 36th Global Congress of Minimally Invasive Gynecology, held in Washington, D.C. on November 13-17, 2007.

"AMS has been committed to bringing physicians clinically validated and meaningful pelvic health innovation since our inception 35 years ago," said Martin J. Emerson, President and CEO. "We are pleased that the office-based benefits of Her Option continue to be proven through rigorous clinical studies, and look forward to sharing these findings with physicians at the AAGL Congress."

Among the topics to be addressed at this year's AAGL poster sessions are:

* Twelve month data indicating significant reduction in menstrual bleeding levels following Her Option Office Cryoablation treatment for abnormal uterine bleeding (AUB)

* Data suggesting extended treatment regimen using Her Option Office Cryoablation is well-tolerated by patients when using only minimal to moderate amounts of pre-treatment anesthesia

* Data on quality of life measures and the impact of AUB on social activities among patients undergoing extended Her Option Office Cryoablation treatment regimens

* Potential improvements in patient-reported mood, pain, cramping and PMS symptoms 12 months following treatment with Her Option Office Cryoablation

* Data on patients with uterine fibroids (< 3cm) with similar results to patients without uterine fibroids when undergoing Her Option Office Cryoablation

* Data demonstrating that patients undergoing Her Option Office Cryoablation were satisfied and perceived their outcomes as reduced to normal more often than pictorial bleeding assessment chart (PBAC) diaries indicate

"The new clinical research supports Her Option in areas critically important to both physicians and their patients with AUB," said Emerson. "We are pleased that Her Option offers physicians a proven and convenient solution for treating AUB in an office setting, and that patients are quite satisfied with the outcome of the procedure."

Her Option Office Cryoablation therapy is offered in over 500 offices in the United States and over 40,000 procedures will have been performed by the end of 2007.

About American Medical Systems

American Medical Systems, headquartered in Minnetonka, Minnesota, is a diversified supplier of medical devices and procedures to cure erectile dysfunction, benign prostatic hyperplasia, incontinence, menorrhagia, prolapse and other pelvic disorders in men and women. These disorders can significantly diminish one's quality of life and profoundly affect social relationships. In recent years, the number of people seeking treatment has increased markedly as a result of longer lives, higher quality-of-life expectations and greater awareness of new treatment alternatives. American Medical Systems' products reduce or eliminate the incapacitating effects of these diseases, often through minimally invasive therapies. The Company's products were used to provide approximately 240,000 patient cures in 2006.

More information about the Company and its products can be found at its website www.AmericanMedicalSystems.com and in the Company's Annual Report on Form 10-K for 2006 and its other SEC filings.