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AmeriPath Announces Advanced Testing for Myeloproliferative Disorders.


PALM BEACH GARDENS, Fla. -- AmeriPath, Inc., a leading national provider of physician-based anatomic pathology, has developed a new assay that detects and quantifies a mutation in the Janus kinase Janus kinase (JAK) is a family of intracellular non-receptor tyrosine kinases, ranging from 120-140 kDa in size, that transduce cytokine-mediated signals via the JAK-STAT pathway.  2 (JAK2) gene common in bcr/abl-negative myeloproliferative disorders (MPDs). The JAK2 V167F Mutation Analysis -- available through both AmeriPath and Specialty Laboratories -- can aid in or confirm the diagnosis of polycythemia vera Polycythemia Vera Definition

Polycythemia vera (PV) is a chronic blood disorder marked by an abnormal increase in three types of blood cells produced by bone marrow: red blood cells (RBCs), white blood cells (WBCs), and platelets.
, essential thrombocythemia essential thrombocythemia Essential thrombocytosis Hematology A primary myeloproliferative disorder of older–age 55-75–adults, or less commonly of young ♀, with a platelet count is > 600 x 109/L; ET has many clinical features of P vera; it , or idiopathic idiopathic /id·io·path·ic/ (id?e-o-path´ik) self-originated; occurring without known cause.

id·i·o·path·ic
adj.
1. Of or relating to a disease having no known cause; agnogenic.
 myelofibrosis Myelofibrosis Definition

Myelofibrosis is a rare disease of the bone marrow in which collagen builds up fibrous scar tissue inside the marrow cavity.
, thereby giving physicians a dynamic new diagnostic tool to more effectively manage treatment decisions for improved patient outcomes.

With its maximized specificity and sensitivity, this new assay offers physicians the following:

--Potentially earlier and more confident diagnosis of bcr/abl-negative MPD MPD maximum permissible dose.

MPD
abbr.
1. maximal permissible dose

2. multiple personality disorder


Multiple personality disorder (MPD) 
 patients

--Rapid, real-time PCR PCR polymerase chain reaction.

PCR
abbr.
polymerase chain reaction


Polymerase chain reaction (PCR) 
 analysis for earlier implementation of appropriate treatment

--A quantitative result that provides a reference point for future patient assessments

"We're very excited about how this test can improve the assessment of myeloproliferative disorders," said Russell L. Maiese, M.D., National Director of Hematopathology, AmeriPath, Inc. "It's an outstanding development for AmeriPath, but more importantly, it's a valuable one for our physicians and their patients."

For more information, visit AmeriPath's Web site at www.ameripath.com.

About AmeriPath, Inc.

AmeriPath, a leading national provider of physician-based anatomic pathology, dermatopathology and molecular diagnostic services diagnostic services,
n.pl the imaging and laboratory capabilities available for determining the cause of an illness.
 to physicians, hospitals, clinical laboratories and surgery centers, supports community-based medicine by helping physicians provide excellent and effective care for their patients. A team of sub-specialized pathologists and Ph.D. scientists provide medical expertise, diagnostic quality, and personal consultation services. AmeriPath's team of more than 400 highly trained, board-certified pathologists and Ph.D.-level scientists provide medical diagnostics services in outpatient laboratories owned, operated and managed by AmeriPath, as well as in hospitals and ambulatory surgical centers.

About Specialty Laboratories, Inc.

Specialty Laboratories supports local pathology and community-based medicine by partnering with pathologists and hospitals to improve patient care and reduce episodes-of-care costs. Specialty offers hospitals an extensive menu of highly advanced clinical tests used by physicians to diagnose, monitor, and treat disease and a single-source solution for esoteric testing needs. Specialty's Web address is www.specialtylabs.com.

Interview Opportunity:

Russell L. Maiese, M.D.

National Director of Hematopathology

AmeriPath, Inc.
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Publication:Business Wire
Date:Mar 29, 2006
Words:354
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