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Altachem Pharma Acquires 100% of World Rights to Bionex, a Revolutionary Blood Decontamination Technology.


Business Editors & Health/Medical Writers

BIOWIRE2K

EDMONTON, Alberta--(BW HealthWire)--Sept. 26, 2001

Warren Jackson, President and Chief Executive Officer of Edmonton-based Altachem Pharma Limited, today announced the successful completion of the formal acquisition of 100% of the world rights to develop, manufacture and sell Bionex(TM), a revolutionary compound designed to potentially be used to clean blood products from contamination by a number of viruses, including the HIV/AIDS virus.

While other biotechnology firms are testing technologies that address the issue of contaminated blood products in a particular manner, there are currently no methodologies being marketed by any company designed to inactivate bacterial or viral pathogens in cellular or labile labile /la·bile/ (la´bil)
1. gliding; moving from point to point over the surface; unstable; fluctuating.
2. chemically unstable.


la·bile (l
 transfusion products. Bionex(TM) is expected to be effective in inactivating these pathogens in contaminated biological fluids such as whole blood. "The Bionex(TM) technology is based on the discovery of novel methods and compositions for treating pathogens that exist, or are transmitted in various human blood transfusion blood transfusion, transfer of blood from one person to another, or from one animal to another of the same species. Transfusions are performed to replace a substantial loss of blood and as supportive treatment in certain diseases and blood disorders. When whole blood is not needed, or when it is not available, plasma, the fluid of the blood without the blood cells, can be given. products and organs," explained Mr. Jackson.

The Canadian Veterinary Medical Association recently indicated that the lack of clinical research is leaving Canada defenseless against the mushrooming number of mysterious diseases that pose a threat to human health. Dr. Alex Livingston, dean of the University of Saskatchewan's Western College of Veterinary Medicine, reported that studies indicate that three out of four "emerging" diseases, in humans, come from animal hosts. Among the most devastating examples are AIDS, variant Creutzfeldt-Jakob Disease Creutzfeldt-Jakob disease: see prion. (vCJD), West Nile virus, Hantaviruses, and E.coli. to name only a few.

"The Bionex(TM) technology includes the introduction of one or more of its compounds into a blood bag, either before or after collecting whole blood, allowing the properties of the compound to decontaminate the blood," added Mr. Jackson. "As such, if this technology is successfully commercialized, it would be possible to provide whole blood suitable for transfusion without the fear of contamination from HIV, hepatitis B and hepatitis C, herpes and other bacteria."

The Bionex(TM) technology also includes methods for treating biological fluids such as plasma, packed red cells, bone marrow and sperm, and inactivating any pathogens in the biological fluid - vital in assuring a zero-risk blood product supply.

Mr. Jackson further explained the primary competitive advantages of Bionex(TM). "In addition to being effective against viruses and bacteria, we believe Bionex(TM) to be the first product of its kind that may prove to be safe for human consumption and/or contact. This is of vital importance in the use of blood products for transfusions."

To date, the Bionex(TM) compounds have shown to be viricidal and bacteriocidal in the initial stages of the experiments. Early experimental research has also indicated that the Bionex(TM) compounds in whole blood do not harm any of the constituents of the blood.

Altachem has acquired the world rights to Bionex(TM) from Bionel, a private biotechnology company in Maryland. These compounds were discovered by Dr. Rene-Guy Bushnel, an internationally-known scientist in the fields of Bio-Acoustics and Biochemistry. Dr. Bushnel is also the inventor of a patented product for surgical gloves and condoms that incorporates a viricide vi·ru·cide (vr-)
n.
An agent that inhibits or destroys viruses.
 compound between two layers of rubber. These surgical gloves and condoms prevent the inadvertent transmission of an active pathogen through the rubber.

"The Bionex(TM) acquisition is another major milestone for Altachem Pharma and completes our strategy of providing a fully integrated approach to the treatment of HIV/AIDS (Kill the virus with ACP-HIP; stop spread of the virus by blood transfusion with Bionex(TM) and, thirdly, to enhance the quality of life for people with the disease via treatment with Anticort(TM)," explained Mr. Jackson. "The urgent need for this product was further highlighted by recent announcements by the FDA and HPB HPB - Harbor Patrol Boat
HPB - Health Promotion Board (Singapore)
HPB - Health Protection Branch, Canada
HPB - Helping Phriendly Book
HPB - High Performance Business
HPB - High Ping Bait (gaming)
HPB - High Ping Bastard (gaming)
HPB - High Plains Biker
HPB - Hollywood Pictures Backlot (Disney's California Adventure)
HPB - Hooper Bay, AK, USA (Airport Code)
HPB - Hrvatska Poštanska Banka (Croatian Post Bank)
HPB - Hull Power Box (A3 Bradley)
 of blood-donation bans on anyone who has spent considerable time in Europe. The ban is expected to have a large impact on the national blood donor pool according to the FDA. USA TODAY reported, in a recent article, that the impact could be far greater regionally. In the New York Metro area, for example, where 25% of blood used is imported from Europe, the blood supply is expected to drop 35%.The successful commercialization of this technology is of significant importance to the intended recipients of blood products as well as the blood treatment industry world-wide," said Mr. Jackson.

Altachem Pharma Ltd. is a publicly traded (CDNX:AAF), Alberta-based pharmaceutical company committed to developing new and improved pharmaceutical products to globally enhance the quality of life. Altachem invests in, develops, manufactures and distributes pharmaceutical products in Canada and internationally. The Company is certified compliant with internationally recognized quality systems standards, ISO 9002:1994, ISO 13488 and EN 46002.

For additional information, contact:
Roger Andrews,                         Don Bain, Vice-President
Manager-Investor Relations             McManus Elliott Communications
Altachem Pharma Ltd.                   Tel. (416) 979-8300 (Ext. 237)
Tel. (780) 486-8331(Ext. 331)          Fax. (416) 979-8638
Toll-free (877) 502-5939(Ext. 331)     E-mail:  don@mcmanuselliott.com
Fax (780) 448-1436
E-mail: roger@altachempharma.com
Web site: www.altachempharma.com


Certain information contained in this press release may be forward-looking and is subject to unknown risks and uncertainties. Although the Company believes that the expectations reflected in such forward-looking statements are reasonable, it can give no assurance that such expectations will prove correct. This is neither an offer to buy or sell a security. For informational purposes only, from sources deemed to be reliable.

"CDNX has neither approved nor disapproved of the information contained herein."

        BACKGROUND SHEET TO ALTACHEM PHARMA/BIONEX NEWS RELEASE

The  Buoyant Blood Treatment & Blood Transfusion Market

    --  The market for blood products is over $ 10 billion and growing
        and with more than 90 million units of blood donated
        world-wide every year, the need for methods to improve the
        safety of blood products is truly significant. (5)

    --  "Any new technology to make the blood supply safer has been
        very well received by the public and has been adopted quickly
        by blood banks," says Richard Davey, Chief Medical Officer for
        American Red Cross. (3)

    --  Recent announcements by FDA and HPB banning blood donations by
        anyone who has spent considerable time in Europe is expected
        to have a large impact on the USA national donor pool
        according to the FDA. The impact could be far greater
        regionally. In New York Metro area, where 25% of blood used is
        imported from Europe, the blood supply is expected to drop
        35%.(4)

The Importance of Zero-Risk Blood Supplies and Products

    --  Number of people worldwide currently living with HIV/AIDS (at
        end 2000): 36.1 million(2)

    --  Number of people worldwide newly infected with HIV virus (at
        end 2000): 5.3 million(2)

    --  Number of people worldwide infected with Hepatitis B virus (at
        end 2000): 2.0 billion (7)

    --  Number of people worldwide with chronic (lifelong) Hepatitis B
        (at end 2000): 350 million (7)

    --  Number of people worldwide infected with Hepatitis C virus (at
        end 2000): 170 million (7)

Consumer Demands - Which Bionex(TM) May Possibly Meet

    --  Contaminant-free biological fluids such as whole blood or
        blood products intended for transfusion. Technology that may
        be proven to provide zero-risk blood transfusion products.

    --  The need to replace a Donor-Screening System that at best,
        only slightly increases the chance of blood safety.

    --  The Canadian Veterinary Medical Association indicated, in a
        recent article, that lack of clinical research is leaving
        Canada defenseless against the mushrooming number of
        mysterious diseases that pose a threat to human health. Dr.
        Alex Livingston, dean of the University of Saskatchewan's
        Western College of Veterinary Medicine, reported that "Studies
        indicate that three out of four "emerging" diseases, in
        humans, come from animal hosts. Among the most devastating
        examples are AIDS, variant Creutzfeldt-Jakob Disease (vCJD),
        West Nile virus, Hantaviruses, and E.coli. to name only a
        few.(6)

    Sources: (1) Bionel; (2) United Nations Joint Initiative on
    Aids(UNAIDS); (3) American Red Cross; (4) USA TODAY; (5) Cerus
    Corp; (6) Edmonton Journal (23-06-2001 A5); (7) World Heath
    Organization (WHO)
COPYRIGHT 2001 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2001, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Date:Sep 26, 2001
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