Alpha lipoic acid. (Nutraceuticals Research).Nutraceutical nu·tra·ceu·ti·cal n. A food or naturally occurring food supplement thought to have a beneficial effect on human health. nutraceutical : Alpha lipoic acid lipoic acid: see coenzyme. Indication: Burning mouth syndrome Source: J Oral Path Med, 2002;31:267-269 Research: Burning mouth syndrome is a type of chronic oral pain diagnosed in the absence of any other clinical disorder. Its symptoms leave the tongue, palate palate (păl`ĭt), roof of the mouth. The front part, known as the hard palate, formed by the upper maxillary bones and the palatine bones, separates the mouth from the nasal cavity. and lips feeling as though they have been burned by hot liquid. Burning mouth syndrome tends to occur in postmenopausal post·men·o·paus·al adj. Of or occurring in the time following menopause. postmenopausal Change of life Gynecology adjective Referring to the time in ♀ when menstrual periods stop for ≥ 1 yr women, and it has been assumed to be related to psychological factors. In a double-blind study double-blind study, n experimental technique in clinical research in which neither the researcher nor the patient knows whether the treatment administered is considered inactive (placebo) or active (medicinal). , researchers asked 42 women and 18 men, ages 22-68, to take either 200 mg of alpha lipoic acid three times daily or placebo for two months. Results: Of the patients taking alpha lipoic acid supplements, 87% had either a complete resolution or partial improvement of symptoms during the two month study. None of those taking placebo had a complete resolution of symptoms, and only 40% had a significant improvement. One year later, 73% of the patients who had improved with alpha lipoic acid maintained that improvement. In contrast, all of the patients who improved while taking placebos deteriorated over the course of a year. |
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