Allergan Reports Fourth Quarter Operating Results.* Total Product Net Sales Net Sales The amount a seller receives from the buyer after costs associated with the sale are deducted. Notes: This amount is calculated by subtracting the following items from gross sales: merchandise returned for credit, allowances for damaged or missing goods, freight Increased 37 Percent for the Fourth Quarter * 2006 BOTOX[R] Sales Top $1 Billion Mark * Board of Directors Declares Fourth Quarter Dividend IRVINE, Calif. -- Allergan, Inc. (NYSE NYSE See: New York Stock Exchange :AGN AGN Again (Amateur Radio) AGN Active Galactic Nucleus AGN Acute Glomerulonephritis AGN Accountants Global Network AGN Air Gabon (ICAO code) ) today announced operating results for the fourth quarter ended December 31, 2006. Allergan also announced that its Board of Directors has declared a fourth quarter dividend of $0.10 per share, payable on March 9, 2007 to stockholders of record on February 16, 2007. Operating Results For the quarter ended December 31, 2006: * Allergan reported $0.89 diluted earnings per share diluted earnings per share An earnings measure calculated by dividing net income less preferred stock dividends for a period by the average number of shares of common stock that would be outstanding if all convertible securities were converted into shares of compared to the $1.03 diluted earnings per share reported for the fourth quarter of 2005. The reported $1.03 diluted earnings per share for the fourth quarter of 2005 included a $0.13 per share benefit related to the resolution of certain tax disputes. In accordance with GAAP GAAP See: Generally Accepted Accounting Principles GAAP See generally accepted accounting principles (GAAP). , Allergan began implementing Statement of Financial Accounting Standards No. 123 (revised 2004), Shared-Based Payment (FAS 123R) in the first quarter of 2006. The reported $0.89 diluted earnings per share for the fourth quarter of 2006 includes a $0.07 per share expense related to the effect of expensing stock options in accordance with FAS 123R. * The pre-tax costs related to expensing stock options included in Allergan's statement of operations See Income statement. for the fourth quarter of 2006 are allocated as follows: $0.9 million to cost of sales, $11.9 million to selling, general and administrative expense and $3.3 million to research and development expense. Allergan's results of operations for the fourth quarter of 2005 do not include any costs related to expensing stock options. * Allergan's adjusted diluted earnings per share were $1.02 in the fourth quarter of 2006, compared to adjusted diluted earnings per share of $1.00 in the fourth quarter of 2005. Adjusted diluted earnings per share of $1.00 in the fourth quarter of 2005 included a $0.09 per share benefit related to the resolution of certain tax disputes. Adjusted diluted earnings per share of $1.02 in the fourth quarter of 2006 includes a $0.07 per share expense related to the effect of expensing stock options in accordance with FAS 123R. Adjusted diluted earnings per share for the fourth quarter of 2006 exclude non-GAAP adjustments to diluted earnings per share which are contained in the financial tables of this press release. Product Sales For the quarter ended December 31, 2006: * Allergan's total product net sales were $816.2 million, which includes $127.0 million of product net sales acquired in connection with the Inamed acquisition. Total product net sales increased 37.2 percent, or 35.5 percent at constant currency, compared to total product net sales in the fourth quarter of 2005. * Pharmaceutical net sales (which excludes product sales acquired in connection with the Inamed acquisition) increased 15.9 percent, or 14.1 percent at constant currency, compared to pharmaceutical net sales in the fourth quarter of 2005. Pharmaceutical net sales increased 18.1 percent, or 16.4 percent at constant currency, compared to pharmaceutical net sales in the fourth quarter of 2005 adjusted to exclude BOTOX[R] sales in Japan as a result of Allergan's development and promotion arrangement with GlaxoSmithKline (GSK GSK GlaxoSmithKline plc (pharmaceutical company) GSK Glycogen Synthase Kinase GSK Gruppentraining Sozialer Kompetenzen (Germany) GSK Greenland Shark (FAO fish species code) ). A reconciliation of the adjustments made from pharmaceutical product net sales reported in accordance with United States United States, officially United States of America, republic (2005 est. pop. 295,734,000), 3,539,227 sq mi (9,166,598 sq km), North America. The United States is the world's third largest country in population and the fourth largest country in area. Generally Accepted Accounting Principles The standard accounting rules, regulations, and procedures used by companies in maintaining their financial records. Generally accepted accounting principles (GAAP) provide companies and accountants with a consistent set of guidelines that cover both broad accounting (GAAP) to adjusted pharmaceutical product net sales is contained in the financial tables of this press release. "We are pleased with our strong sales growth and performance in 2006 across a broad range of businesses, products and geographic regions," said David E.I. Pyott, Allergan's Chairman of the Board and Chief Executive Officer. "Furthermore, we are looking forward in 2007 to building on our strong position as the global leader in the high growth medical aesthetics market and also on our momentum as the fastest growing global ophthalmic pharmaceutical company." Achieving a major milestone, 2006 sales of BOTOX[R] (botulinum toxin type A botulinum toxin type A Botox, Botox Cosmetic, Dysport (UK), Vistabel (UK) Pharmacologic class: Neurotoxin Therapeutic class: Neuromuscular blocker Pregnancy risk category C Action) crossed the billion-dollar mark on the strength of growth in sales for both therapeutic and cosmetic use, including GSK's sales in Japan and China as a result of Allergan's development and promotion arrangement with GSK. For full year 2006, therapeutic sales accounted for approximately 52% of total BOTOX[R] sales and cosmetic sales accounted for approximately 48% of total BOTOX[R] sales. The BOTOX[R] therapeutic and cosmetic growth rate calculations are contained in the financial table of this press release.Product and Pipeline Update During the fourth quarter of 2006: * On October 5, 2006, Allergan announced completion of the integration of Inamed's commercial and research and development operations, uniting the companies' facial aesthetics, breast aesthetics and obesity intervention product portfolios under the Allergan name and within a newly established corporate division, Allergan Medical. * On October 20, 2006, Allergan announced that Health Canada Health Canada (French: Santé Canada) is the department of the government of Canada with responsibility for national public health. Health Canada's goal is to improve Canadian life by improving Canadian longevity, lifestyle and use of public healthcare. granted a medical device license with conditions to sell and market INAMED[R] Silicone-Filled Breast Implants Breast Implants Definition Breast implantation is a surgical procedure for enlarging the breast. Breast-shaped sacks made of a silicone outer shell and filled with silicone gel or saline (salt water), called implants, are used. , including the INAMED[R] Round, Smooth and Textured Silicone-Filled Breast Implants and INAMED[R] Style 410 Shaped and Textured Silicone-Filled Breast Implants, for use in breast augmentation AUGMENTATION, old English law. The name of a court erected by Henry VIII., which was invested with the power of determining suits and controversies relating to monasteries and abbey lands. , reconstruction and revision surgery. * GSK launched BOTOX[R] in China for blepharospasm bleph·a·ro·spasm n. Spasmodic winking caused by the involuntary contraction of an eyelid muscle. blepharospasm spasm of the orbicularis oculi muscle of the eyelid. and hemifacial spasm Hemifacial spasm or HFS is a neurological disorder in which blood vessels constrict the seventh cranial nerve and cause varying degrees of facial spasming, typically originating around the eye of the afflicted side of the face. , for the first time, bringing BOTOX[R] treatment to the many patients in China suffering from these debilitating de·bil·i·tat·ing adj. Causing a loss of strength or energy. Debilitating Weakening, or reducing the strength of. Mentioned in: Stress Reduction neuromuscular neuromuscular /neu·ro·mus·cu·lar/ (-mus´ku-ler) pertaining to nerves and muscles, or to the relationship between them. neu·ro·mus·cu·lar adj. 1. conditions. * On November 17, 2006, Allergan announced that the United States Food and Drug Administration United States Food and Drug Administration (FDA), n.pr a unit of the Public Health Service created to protect the health of the nation against impure and unsafe foods, drugs, and cosmetics. (FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. ) approved Allergan's INAMED[R] Silicone-Filled Breast Implants for use in breast augmentation, reconstruction and revision surgery. * On December 21, 2006, Allergan announced that the FDA issued an approvable letter for COMBIGAN[TM] (brimonidine tartrate/timolol maleate maleate /mal·e·ate/ (mal´e-at) any salt or ester of maleic acid. ma·le·ate n. 1. A salt of maleic acid. 2. An ester of maleic acid. ophthalmic solution ophthalmic solution n. A sterile solution that is free from foreign particles and is compounded and dispensed for eyedrops. ) 0.2%/0.5% for the reduction of elevated intraocular pressure intraocular pressure n. The pressure of the intraocular fluid within the eye. intraocular pressure (in´tr (IOP IOP intraocular pressure. IOP Intraocular pressure, see there ) in patients with glaucoma glaucoma (glôkō`mə), ocular disorder characterized by pressure within the eyeball caused by an excessive amount of aqueous humor (the fluid substance filling the eyeball). or ocular hypertension Ocular hypertension (OHT) is intraocular pressure higher than normal in the absence of optic nerve damage or visual field loss.[1][2] Current consensus in ophthalmology defines normal introcular pressure (IOP) as that between 10 mmHg and 21 mmHg. who require adjunctive or replacement therapy due to inadequately controlled IOP. Following the end of the fourth quarter of 2006: * On January 2, 2007, Allergan completed the acquisition of Groupe Corneal corneal pertaining to the cornea. See also keratitis, keratopathy. corneal anomaly includes microcornea, coloboma, megalocornea, dermoid, congenital opacity. corneal black body see corneal sequestrum (below). Laboratoires, obtaining exclusive rights to market and manufacture JUVEDERM[TM]. * On January 17, 2007, Allergan announced nationwide availability of its 'next-generation' hyaluronic acid hyaluronic acid: see mucopolysaccharide. Hyaluronic acid A polysaccharide which is an integral part of the gel-like substance of animal connective tissue; it supposedly serves as a lubricant and shock absorbent in the joints. dermal dermal /der·mal/ (der´mal) pertaining to the dermis or to the skin. der·mal or der·mic adj. Of or relating to the skin or dermis. filler family of products, JUVEDERM[TM] ULTRA and JUVEDERM[TM] ULTRA PLUS. Memantine Update Following the fourth quarter, Allergan completed the initial analysis of the data from the first of two phase III clinical trials Noun 1. phase III clinical trial - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the of memantine for the preservation of visual function in patients with glaucoma. The use of memantine as a neuroprotective agent neuroprotective agent Neurology Any agent or drug that protects the brain from secondary injury caused by stroke. See Stroke. would be the first drug approved to prevent the loss of visual function, and potentially lead to a paradigm shift A dramatic change in methodology or practice. It often refers to a major change in thinking and planning, which ultimately changes the way projects are implemented. For example, accessing applications and data from the Web instead of from local servers is a paradigm shift. See paradigm. in the treatment of this important disease. To date, glaucoma treatment has focused on medications or surgery to lower intraocular pressure. Two measures of visual function were selected in the statistical analysis plan to assess the efficacy of memantine in glaucoma. The functional measure chosen as the primary endpoint did not show a benefit of memantine in preserving visual function. In a number of analyses using the secondary functional measure, memantine demonstrated a statistically significant benefit of the high dose compared to placebo. While Allergan is encouraged that a functional benefit of memantine was demonstrated in this secondary analysis, there are a number of challenges that remain. First, Allergan needs to complete the full assessment of the data from this complex clinical trial that contains four years of data on approximately one thousand glaucoma patients. Once completed, Allergan will review the data with the FDA and other regulatory agencies regulatory agency Independent government commission charged by the legislature with setting and enforcing standards for specific industries in the private sector. The concept was invented by the U.S. . Importantly, the safety and efficacy of memantine must be confirmed in the second phase III Noun 1. phase III - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA trial. Until Allergan completes the data analysis and agency meetings, which could take up to twelve months, it cannot assess the impact to filing and approval timing. Outlook For the full year of 2007, Allergan estimates: * Total product net sales between $3,460 million and $3,630 million.
-- Pharmaceutical product net sales between $2,885 million and
$2,985 million. Pharmaceutical sales exclude sales of
products acquired in connection with the Inamed
acquisition.
-- ALPHAGAN[R] Franchise product net sales between $295
million and $315 million.
-- LUMIGAN[R] Franchise product net sales between $355 million
and $375 million.
-- RESTASIS[R] product net sales between $320 million and $340
million.
-- BOTOX[R] product net sales between $1,100 million and
$1,145 million.
-- Breast aesthetic product net sales between $250 million and
$280 million.
-- Obesity intervention product net sales between $215 million
and $235 million.
-- Dermal filler product net sales between $110 million and
$130 million.
* Cost of sales ratio to product net sales between 17.5% and 18.0%. * Other revenue between $50 million and $60 million. * Selling, General and Administrative ratio to product net sales between 40% and 41%. * Research and Development ratio to product net sales at approximately 16.5%. This guidance excludes any potential in-process research and development associated with the Corneal acquisition. * Amortization of acquired intangible assets Intangible Asset An asset that is not physical in nature. Notes: Examples are things like copyrights, patents, intellectual property, and goodwill. These are the opposite of tangible assets. at approximately $20 million. This guidance excludes the amortization of acquired intangible assets associated with the Inamed acquisition of approximately $78 million and any potential amortization associated with the Corneal acquisition. * Adjusted diluted earnings per share guidance between $4.27 and $4.31. Adjusted diluted earnings per share guidance excludes the non-GAAP adjustments to diluted earnings per share guidance that are contained in the financial tables of this press release. * Diluted shares outstanding between approximately 153 million and 155 million. * Effective tax rate on adjusted earnings at approximately 28%. For the first quarter of 2007, Allergan estimates: * Total product net sales between $830 million and $850 million. * Adjusted diluted earnings per share guidance between $0.88 and $0.90. Adjusted diluted earnings per share guidance excludes the non-GAAP adjustments to diluted earnings per share guidance that are contained in the financial tables of this press release. Forward-Looking Statements forward-looking statement A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections. In this press release, the statements regarding new product development, market potential, expected growth, efficiencies, costs and savings, the statements by Mr. Pyott as well as the outlook for Allergan's earnings per share and revenue forecasts, among other statements above, are forward-looking statements. Because forecasts are inherently estimates that cannot be made with precision, Allergan's performance at times differs materially from its estimates and targets, and Allergan often does not know what the actual results will be until after a quarter's end and year's end. Therefore, Allergan will not report or comment on its progress during a current quarter except through public announcement. Any statement made by others with respect to progress during a current quarter cannot be attributed to Allergan. Any other statements in this press release that refer to Allergan's expected, estimated or anticipated future results are forward-looking statements. All forward-looking statements in this press release reflect Allergan's current analysis of existing trends and information and represent Allergan's judgment only as of the date of this press release. Actual results may differ materially from current expectations based on a number of factors affecting Allergan's businesses, including, among other things, changing competitive, market and regulatory conditions; the timing and uncertainty of the results of both the research and development and regulatory processes; domestic and foreign health care and cost containment cost containment, n the features of a dental benefits program or of the administration of the program designed to reduce or eliminate certain charges to the plan. reforms; technological advances and patents obtained by competitors; the performance, including the approval, introduction, and consumer and physician acceptance, of new products and the continuing acceptance of currently marketed products; the effectiveness of advertising and other promotional campaigns; the timely and successful implementation of strategic initiatives; the results of any pending or future litigations, investigations or claims; the uncertainty associated with the identification of and successful consummation and execution of external corporate development initiatives and strategic partnering transactions; and Allergan's ability to obtain and successfully maintain a sufficient supply of products to meet market demand in a timely manner. In addition, matters generally affecting the economy, such as changes in interest and currency exchange rates; international relations international relations, study of the relations among states and other political and economic units in the international system. Particular areas of study within the field of international relations include diplomacy and diplomatic history, international law, ; and the state of the economy worldwide, can materially affect Allergan's results. Therefore, the reader is cautioned not to rely on these forward-looking statements. Allergan expressly disclaims any intent or obligation to update these forward-looking statements except as required to do so by law. Additional information concerning the above-referenced risk factors and other risk factors can be found in press releases issued by Allergan, as well as Allergan's public periodic filings with the Securities and Exchange Commission, including the discussion under the heading "Risk Factors" in Allergan's 2005 Form 10-K Form 10-K A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information. Form 10-K See 10-K. and Allergan's Form 10-Q Form 10-Q See 10-Q. for the period ended September 29, 2006. Copies of Allergan's press releases and additional information about Allergan is available at www.allergan.com or you can contact the Allergan Investor Relations Investor relations The process by which the corporation communicates with its investors. Department by calling 714-246-4636. About Allergan, Inc. With more than 55 years of experience providing high-quality, science-based products, Allergan, Inc., with headquarters in Irvine, California Irvine is an incorporated city in Orange County, California, United States. It is a planned city, mainly developed by the Irvine Company since the 1960s. Formally incorporated on December 28 1971, the 69.7 square mile (180.5 km²) city has a population of 202,079 (as of 2007). , discovers, develops and commercializes products in the ophthalmology ophthalmology (ŏf'thălmŏl`əjē), branch of medicine specializing in the anatomy, function and diseases of the eye. Ophthalmologists specialize in the medical and surgical treatment of eye disorders, vision measurements for , neurosciences, medical dermatology dermatology (dûrmətŏl`əjē), branch of medicine concerned with diagnosis and treatment of diseases and disorders of the skin. , medical aesthetics, obesity intervention and other specialty markets that deliver value to its customers, satisfy unmet medical needs, and improve patients' lives. [R] and TM Marks owned by Allergan, Inc. JUVEDERM[TM] Mark owned by Corneal Industrie SAS (1) (SAS Institute Inc., Cary, NC, www.sas.com) A software company that specializes in data warehousing and decision support software based on the SAS System. Founded in 1976, SAS is one of the world's largest privately held software companies. See SAS System. [TABLE OMITTED] (a) Integration and transition costs related to the acquisition of Inamed, consisting of Cost of sales of $0.2 million and Selling, general and administrative expense of $5.0 million (b) Costs related to the acquisition of Groupe Corneal Laboratoires of $0.1 million (c) Amortization of acquired intangible assets (d) Restructuring charges (e) Unrealized gain Unrealized Gain A profit that results from holding on to an asset rather than cashing it in and using the funds. Notes: Let's say you own a stock that has doubled, but you haven't sold it yet. This is said to be an unrealized gain. (loss) on the mark-to-market adjustment to derivative instruments Derivative instruments Contracts such as options and futures whose price is derived from the price of an underlying financial asset. (f) Reversal of accrued costs for a previously disclosed contingency involving non-income taxes in Brazil (g) Total tax effect for non-GAAP pre-tax adjustments and other income tax adjustments, consisting of the following amounts (in millions): [TABLE OMITTED] (h) Transition/duplicate operating expenses Operating expenses The amount paid for asset maintenance or the cost of doing business, excluding depreciation. Earnings are distributed after operating expenses are deducted. related to restructuring and streamlining of European operations, consisting of Cost of sales of $0.2 million; Selling, general and administrative expense of $1.9 million and Research and development expense of $0.4 million (i) Restructuring charges of $6.2 million and related inventory adjustments of $(0.1) million (j) Costs related to the acquisition of Inamed of $0.4 million (k) Gain on sale of a former manufacturing plant in Argentina of $0.6 million (l) Loss on sales of assets primarily used for AMO AMO - America's Multimedia Online Contract Manufacturing of $0.1 million (m) Reversal of interest expense related to tax settlements (n) Total tax effect for non-GAAP pre-tax adjustments and other income tax adjustments, consisting of the following amounts (in millions): [TABLE OMITTED] "GAAP" refers to financial information presented in accordance with generally accepted accounting principles in the United States. This press release includes non-GAAP financial measures, as defined in Regulation G promulgated prom·ul·gate tr.v. prom·ul·gat·ed, prom·ul·gat·ing, prom·ul·gates 1. To make known (a decree, for example) by public declaration; announce officially. See Synonyms at announce. 2. by the Securities and Exchange Commission, with respect to the three and twelve months ended December 31, 2006 and December 31, 2005 and with respect to anticipated results for the first quarter and full year of 2007. Allergan believes that its presentation of non-GAAP financial measures provides useful supplementary information to investors regarding its operational performance because it enhances an investor's overall understanding of the financial performance and prospects for the future of Allergan's core business activities by providing a basis for the comparison of results of core business operations Business operations are those activities involved in the running of a business for the purpose of producing value for the stakeholders. Compare business processes. The outcome of business operations is the harvesting of value from assets between current, past and future periods. The presentation of historical non-GAAP financial measures is not meant to be considered in isolation from or as a substitute for results prepared in accordance with accounting principles generally accepted in the United States. In this press release, Allergan reported the non-GAAP financial measure "adjusted net earnings" and related "adjusted earnings per share" - both basic and diluted. Allergan uses adjusted earnings to enhance the investor's overall understanding of the financial performance and prospects for the future of Allergan's core business activities. Adjusted earnings is one of the primary indicators management uses for planning and forecasting in future periods, including trending and analyzing the core operating performance of Allergan's business from period to period without the effect of the non-core business items indicated. Management uses adjusted earnings to prepare operating budgets and forecasts and to measure Allergan's performance against those budgets and forecasts on a corporate and segment level. Allergan also uses adjusted earnings for evaluating management performance for compensation purposes. Despite the importance of adjusted earnings in analyzing Allergan's underlying business, the budgeting and forecasting process and designing incentive compensation, adjusted earnings has no standardized meaning defined by GAAP. Therefore, adjusted earnings has limitations as an analytical tool, and should not be considered in isolation, or as a substitute for analysis of Allergan's results as reported under GAAP. Some of these limitations are: * it does not reflect cash expenditures, or future requirements, for expenditures relating to relating to relate prep → concernant relating to relate prep → bezüglich +gen, mit Bezug auf +acc restructurings, and certain acquisitions, including severance and facility transition costs associated with acquisitions; * it does not reflect gains or losses on the disposition of assets associated with restructuring and business exit activities; * it does not reflect the tax benefit or tax expense associated with the items indicated; * it does not reflect the reduction of cash and earnings associated with a contribution to the Allergan Foundation; * it does not reflect the impact on earnings of charges resulting from certain matters Allergan considers not to be indicative of its on-going operations; and * other companies in Allergan's industry may calculate adjusted earnings differently than it does, which may limit its usefulness as a comparative measure. Allergan compensates for these limitations by using adjusted earnings only to supplement net income (loss) on a basis prepared in conformance with GAAP in order to provide a more complete understanding of the factors and trends affecting its business. Allergan strongly encourages investors to consider both net income (loss) and cash flows determined under GAAP as compared to adjusted earnings, and to perform their own analysis, as appropriate. [TABLE OMITTED] (a) Integration and transition costs related to the acquisition of Inamed, consisting of Cost of sales of $0.9 million; Selling, general and administrative expense of $19.6 million and Research and development expense of $0.2 million (b) Inamed fair-market value inventory adjustment roll out of $47.9 million (c) Costs related to the acquisition of Groupe Corneal Laboratoires of $0.1 million (d) Transition/duplicate operating expenses related to restructuring and streamlining of European operations, consisting of Selling, general and administrative expense of $5.7 million and Research and development expense of $0.5 million (e) Contribution to Allergan Foundation of $28.5 million (f) In-process research and development charge of $579.3 million related to the acquisition of Inamed (g) Amortization of acquired intangible assets (h) Restructuring charges (i) Reversal of interest income on previously paid state income taxes and reversal of interest expense related to the resolution of uncertain tax positions (j) Unrealized gain (loss) on the mark-to-market adjustment to derivative instruments (k) Accrued costs for a previously disclosed contingency involving non-income taxes in Brazil (l) Total tax effect for non-GAAP pre-tax adjustments and other income tax adjustments, consisting of the following amounts (in millions): [TABLE OMITTED] (m) Transition/duplicate operating expenses related to restructuring and streamlining of European operations, consisting of Cost of Sales of $0.3 million; Selling, general and administrative expense of $3.8 million and Research and development expense of $1.5 million (n) Restructuring charge of $43.8 million and related inventory write-offs of $0.2 million (o) Gain on sale of assets primarily used for AMO contract manufacturing ($5.7 million), gain on sale of distribution business in India ($7.9 million), and gain on sale of a former manufacturing plant in Argentina ($0.6 million) (p) Costs related to the acquisition of Inamed of $0.4 million (q) Buy-out of license agreement with Johns Hopkins Noun 1. Johns Hopkins - United States financier and philanthropist who left money to found the university and hospital that bear his name in Baltimore (1795-1873) Hopkins 2. (r) Interest income related to previously paid state income taxes and reversal of interest expense related to tax settlements (s) Termination of ISTA ISTA International Safe Transit Association ISTA Indiana State Teachers Association ISTA International Seed Testing Association ISTA International Sail Training Association ISTA Information, Science, and Technology Agency (British Columbia) Vitrase collaboration agreement (including interest income of $0.1 million) (t) Gain on sale of third party equity investment (u) Total tax effect for non-GAAP pre-tax adjustments and other income tax adjustments, consisting of the following amounts (in millions): [TABLE OMITTED] (v) Minority interest related to gain on sale of distribution business in India [TABLE OMITTED] [TABLE OMITTED] (a) Including inventory adjustments reported in cost of sales of $(0.1) million and $0.2 million for the three and twelve month periods ending December 31, 2005, respectively. (b) The number of shares used to calculate adjusted diluted earnings per share includes the dilutive effect Dilutive effect Result of a transaction that decreases earnings per common share (EPS). of outstanding stock options and the assumed conversion of convertible notes. [TABLE OMITTED] [TABLE OMITTED] [TABLE OMITTED] [TABLE OMITTED] [TABLE OMITTED] [TABLE OMITTED] (a) Adjustments to pharmaceutical product net sales consist of Botox net sales in Japan in 2005 of $11.4 and $38.8 million for the three and twelve month periods ended December 31, 2005, respectively. (b) Adjustments to Botox/Neuromodulator net sales consist of Therapeutic net sales in Japan in 2005 of $38.8 million for the twelve month period ended December 31, 2005. (c) The breakout between therapeutic and cosmetic net sales is subjectively determined based upon management's estimate of use based on customer specialty, product SKU (StockKeeping Unit) The number of one specific product available for sale. If a hardware device or software package comes in different versions, there is an SKU for each one. SKU - stock-keeping unit and limited third party customer surveys. In this press release, Allergan reported sales performance using the non-GAAP financial measure of constant currency sales. Constant currency sales represent current period reported sales adjusted for the translation effect of changes in average foreign exchange rates between the current period and the corresponding period in the prior year. Allergan calculates the currency effect by comparing adjusted current period reported amounts, calculated using the monthly average foreign exchange rates for the corresponding period in the prior year, to the actual current period reported amounts. Management refers to growth rates Growth Rates The compounded annualized rate of growth of a company's revenues, earnings, dividends, or other figures. Notes: Remember, historically high growth rates don't always mean a high rate of growth looking into the future. at constant currency so that sales results can be viewed without the impact of changing foreign currency exchange rates, thereby facilitating period-to-period comparisons of Allergan's sales. Generally, when the dollar either strengthens or weakens against other currencies, the growth at constant currency rates will be higher or lower, respectively, than growth reported at actual exchange rates. Allergan also reported sales performance using the non-GAAP financial measure of adjusted total pharmaceutical product net sales. Adjusted total pharmaceutical product net sales represents reported sales adjusted to exclude prior period net sales for Japan. Allergan shifted to a third party license and distribution business model for its operations in Japan in 2005 and accordingly has recorded no current period pharmaceutical product net sales for the Japan operations. Allergan uses adjusted total pharmaceutical product net sales to enhance the investor's overall understanding of the financial performance and prospects for the future of Allergan's core business activities. Specifically, Allergan believes that a report of adjusted total pharmaceutical product net sales provides consistency in its financial reporting and facilitates the comparison of net sales of core business operations between its current, past and future periods. Adjusted total pharmaceutical product net sales is one of the primary indicators management uses for planning and forecasting in future periods. Allergan also uses adjusted total pharmaceutical product net sales for evaluating management performance for compensation purposes. [TABLE OMITTED] [TABLE OMITTED] (a) GAAP diluted earnings per share guidance excludes any potential impact of future unrealized gains or losses on derivative instruments, restructuring charges and integration and transition costs that may occur but that are not currently known or determinable Liable to come to an end upon the happening of a certain contingency. Susceptible of being determined, found out, definitely decided upon, or settled. determinable adj. . |
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