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Alder Hey hope for arthritis risk kids.


Byline: By HELEN HUNT

EXPERTS at Alder Hey hospital have launched a major study to help arthritic youngsters avoid developing damaged bones.

Children with the condition take steroids to combat the pain and damaging effects, but it leaves about 50% of them with brittle bones brit·tle bones
n.
See osteogenesis imperfecta.


brittle bones 1 Osteogenesis imperfecta Bones with ↑ osseous fragility, a phenomenon seen in osteogenesis imperfecta, due to genetic defects–eg, point
, known as osteopenia.

Doctors at the world-famous children's hospital are now running a pounds 500,000 clinical trial funded by the Arthritis Research Campaign Arthritis Research Campaign is a British medical research charity dedicated to curing arthritis. External links
  • Official site
.

They hope to draw up guidelines for treating osteopenia and reduce the damage it causes.

Consultant Michael Beresford said: "Children with rheumatic rheu·mat·ic
adj.
Relating to or characterized by rheumatism.

n.
One who is affected by rheumatism.



rheumatic

pertaining to or affected with rheumatism.
 diseases often suffer thinning of their bones.

"This is due to factors including the underlying inflammatory process itself, nutrition and reduced physical activity, but steroids play a significant role.

"Steroids are extremely important in getting their disease under control, but they then have a greater risk of osteoporosis and are at increased risk of fractures."

The trial will compare two vitamin D vitamin D

Any of a group of fat-soluble alcohols important in calcium metabolism in animals to form strong bones and teeth and prevent rickets and osteoporosis. It is formed by ultraviolet radiation (sunlight) of sterols (see steroid) present in the skin.
 supplements, to see which is best at building up bones.

Both drugs have helped adults with osteoporosis, but doctors need to prove they work for children before they can prescribe them.

A third group of youngsters will receive a dummy drug as part of the test.

Youngsters from Merseyside and Cheshire are being recruited to take part in Alder Hey's trial.

The three-year study will help those with arthritis and other related illnesses.

There are thousands of children worldwide receiving steroids for chronic rheumatic diseases.

helenhunt@liverpoolecho.co.uk
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Publication:Liverpool Echo (Liverpool, England)
Date:Apr 15, 2008
Words:242
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