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Alcon's VEGAMOX(TM) Ophthalmic Solution Approved in Japan for Eye Infections.


FORT WORTH, Texas -- Alcon, Inc. (NYSE:ACL) announced today that the Ministry of Health, Labor and Welfare in Japan has approved its VEGAMOX(TM) (moxifloxacin moxifloxacin /mox·i·flox·a·cin/ (-flok´sah-sin) a fluoroquinoloneantibacterial effective against many gram-positive and gram-negative bacteria; used as the hydrochloride salt. hydrochloride ophthalmic solution) 0.5 % for the treatment of bacterial infections of the eye including, among others, conjunctivitis
acute contagious conjunctivitis , acute epidemic conjunctivitis pinkeye; a highly contagious form of conjunctivitis caused by Haemophilus aegyptius.
acute hemorrhagic conjunctivitis  a contagious form due to infection with enteroviruses.
allergic conjunctivitis  conjunctival inflammation, itching, tearing, and redness caused by allergens.
 and keratitis
keratitis bullo´sa  presence of blebs upon the cornea.
dendriform keratitis , dendritic keratitis herpetic keratitis which results in a branching ulceration of the cornea.
herpetic keratitis 
1. that, commonly with dendritic ulceration (dendriform or dendritic k.), due to infection with herpes simplex virus.
 (including corneal ulcer), as well as for surgical prophylaxis.

VEGAMOX(TM) solution is a fourth-generation fluoroquinolone fluoroquinolone /flu·o·ro·quin·o·lone/ (-kwin´o-lon) any of a subgroup of fluorine-substituted quinolones, having a broader spectrum of activity than nalidixic acid.

fluor·o·quin·o·lone (fl
 eye drop formulated at a 0.5% concentration, providing high drug concentration throughout relevant ocular
1. of, pertaining to, or affecting the eye.
2. eyepiece.


oc·u·lar (ky
 structures. Its near-neutral pH of 6.8 provides for ocular comfort. In clinical studies, VEGAMOX(TM) solution has demonstrated excellent efficacy and therapeutic penetration.

Alcon Japan President Scott Manning said the approval will present an opportunity for increased sales in Japan, the world's second largest ocular infective
1. capable of producing infection.
2. infectious (1).


in·fec·tive (n-fk
">anti-infective an·ti-in·fec·tive (nt-n-f market.

"The approval of VEGAMOX(TM) solution provides Alcon Japan with an important opportunity to expand its pharmaceutical offerings in Japan to include anti-infectives and more fully serve Japanese ophthalmologists," said Manning. "Because of its clinical profile and our experience with it in the U.S., where it is the number one prescribed ocular anti-infective, as well as the strong preference for fluoroquinolones by Japanese ophthalmologists, we expect it to be a strong participant in the anti-infective market in Japan. In anticipation of the commercial launch of VEGAMOX(TM) solution this year, we are expanding our sales force in order to reach physicians with information about how this product may contribute to the treatment of bacterial eye diseases."

VEGAMOX(TM) solution is currently approved as VIGAMOX(R) solution in more than 40 countries around the world.

About Alcon

Alcon, Inc. (NYSE:ACL) is the world's leading eye care company with sales of $4.4 billion in 2005. Alcon, which has been dedicated to the ophthalmic industry for more than 50 years, develops, manufactures and markets pharmaceuticals, surgical equipment and devices, contacts lens care solutions and other vision care products that treat diseases, disorders and other conditions of the eye. For more information on Alcon, Inc., visit the Company's web site at www.alconinc.com. Moxifloxacin hydrochloride ophthalmic solution 0.5 % is licensed to Alcon, Inc. by Bayer HealthCare, AG.

Caution Concerning Forward-Looking Statements. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements involve known and unknown risks, uncertainties and other factors which may cause our actual results, performance or achievements to be materially different from any future results, performances or achievements expressed or implied by our forward-looking statements. These statements reflect the views of our management as of the date of this press release with respect to future events and are based on assumptions and subject to risks and uncertainties. Given these uncertainties, you should not place undue reliance on these forward-looking statements.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Jul 26, 2006
Words:457
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