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Air pollution impairs lung development in children.


Gauderman WJ, Avol E, Gilliland F, Vora H, Thomas D Thomas D. (born Thomas Dürr, December 30 1968 in Ditzingen close to Stuttgart, Germany) is a rapper in the German hip hop group Die Fantastischen Vier. He frequently works on solo projects. Life
After finishing Realschule he took on an apprenticeship as a barber.
, Berhane K, McConnell R, Kuenzli N, Lurmann F, Rappaport E, Margolis H, Bates Bates   , Katherine Lee 1859-1929.

American educator and writer best known for her poem "America the Beautiful," written in 1893 and revised in 1904 and 1911.
 D, Peters J. 2004. The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med 351(11):1057-1067.

Mounting evidence suggests that exposure to air pollution has long-term effects on lung development in children; reductions in lung function have been observed in studies in Europe and the United States. To further investigate these effects, this NIEHS-supported research team performed a prospective epidemiologic study epidemiologic study A study that compares 2 groups of people who are alike except for one factor, such as exposure to a chemical or the presence of a health effect; the investigators try to determine if any factor is associated with the health effect  on 1,759 children from 12 communities in Southern California.

The communities had a wide range of exposures to air pollutants including particulate matter, acid aerosols, ozone, and nitrogen dioxide. The team recruited fourth-graders and performed lung function tests Lung function tests
Tests of how much air the lungs can move in and out, and how quickly and efficiently this can be done. Lung function tests are usually done by breathing into a device that measures air flow.

Mentioned in: Pulmonary Fibrosis
 annually for eight years.

Over the eight-year period, decreases in a measurement of lung function known as forced expiratory volume forced expiratory volume
n. Abbr. FEV
The maximum volume of air that can be expired from the lungs in a specific time interval when starting from maximum inspiration.
 ([FEV FEV forced expiratory volume.

FEV
abbr.
forced expiratory volume



FEV

forced expiratory volume.
.sub.1]) were associated with exposure to nitrogen dioxide, acid aerosols, particulate matter, and elemental carbon. The decreases noted were statistically and clinically significant. For example, the risk of diminished [FEV.sub.1] was almost five times higher at the highest level of particulate matter exposure than at the lowest level. The magnitude of the effects on development of lung function was comparable to that reported for exposure to maternal smoking.

The authors conclude that these results can be generalized to children living in other parts of the United States that have high air pollution levels. The results indicate that current ambient air pollution levels can have chronic and adverse effects on lung development in children, leading to clinically significant lung function deficits in adulthood. Given the severity of the effects and the importance of lung development as a determinant of morbidity and mortality Morbidity and Mortality can refer to:
  • Morbidity & Mortality, a term used in medicine
  • Morbidity and Mortality Weekly Report, a medical publication
See also
  • Morbidity, a medical term
  • Mortality, a medical term
 during adulthood, it is important to continue identifying strategies for reducing air pollution.
COPYRIGHT 2004 National Institute of Environmental Health Sciences
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2004, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Title Annotation:Headliners / Respiratory Health
Author:Phelps, Jerry
Publication:Environmental Health Perspectives
Date:Dec 1, 2004
Words:311
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