Agilent Technologies and Exelixis Sign Agreement for Customized DNA Microarrays.Business Editors and Health/Medical Writers PALO ALTO Palo Alto, city, California Palo Alto (păl`ō ăl`tō), city (1990 pop. 55,900), Santa Clara co., W Calif.; inc. 1894. Although primarily residential, Palo Alto has aerospace, electronics, and advanced research industries. , Calif.--(BW HealthWire)--Oct. 12, 2000 Agilent's DNA Microarrays to Further Exelixis' Design of Commercial Genomics Applications Agilent Technologies This article needs sources or references that appear in reliable, third-party publications. Alone, primary sources and sources affiliated with the subject of this article are not sufficient for an accurate encyclopedia article. Inc. (NYSE NYSE See: New York Stock Exchange :A) today announced that it has entered into an agreement to supply customizable DNA microarrays to Exelixis Inc. (Nasdaq:EXEL), a leader in the fields of model system genetics and comparative genomics Comparative genomics is the study of relationships between the genomes of different species or strains. Comparative genomics is an attempt to take advantage of the information provided by the signatures of selection to understand the function and evolutionary processes that act on . Exelixis will use Agilent's flexible microarray platform for expression profiling Microarray technology is often used for gene expression profiling. It makes use of the sequence resources created by the genome sequencing projects and other sequencing efforts to answer the question, experiments in various model organisms to supplement existing Exelixis platforms for high-throughput functional genomics Noun 1. functional genomics - the branch of genomics that determines the biological function of the genes and their products genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences) analysis. Financial details of the agreement were not disclosed. "We are pleased to have Exelixis, a pioneer in the field of comparative genomics, select Agilent's microarrays as research tools to perform high-throughput gene expression profiling analysis," said Bill Buffington, vice president of Agilent's Life Sciences Business Unit. "As a leading provider of customized microarray solutions, consulting services, informatics software and tools for gene expression analysis, Agilent is well placed to help Exelixis identify those key pathways associated with diseases or biologies." "The Agilent technology provides another tool in our powerful array of integrated genetics and genomics technologies," said Geoffrey Duyk, M.D., Ph.D., chief scientific officer of Exelixis Inc. "We can use the expression profiling analysis in a variety of ways, including our 'Mechanism of Action program,' to study toxicological profiles of drugs, or as a step in validating our proprietary targets in therapeutic areas, such as oncology and inflammation." Agilent Technologies in Gene Expression Agilent Technologies is a leading provider of solutions including consulting services, informatics software and tools for gene expression analysis, a fast-growing field of study that allows researchers to identify key gene transcriptional regulatory events or pathways associated with diseases or biologies. Researchers can do rapid, iterative, hypothesis-driven gene expression research by first determining their research goals and then having custom-designed microarrays developed by Agilent to be delivered within days. Agilent is also a leading original equipment manufacturer of high-quality bioanalyzers and microarray scanners. Agilent supports the collaborative research efforts by the National Human Genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes. Research Institute (NHGRI NHGRI National Human Genome Research Institute ) and others to analyze genome-wide patterns of mRNA expression, and is actively driving open data standards for gene expression research in alliance with Rosetta Inpharmatics Inc. About Exelixis, Inc. Exelixis, Inc. is a leading life sciences biotechnology company focused on product development through its expertise in comparative genomics and model system genetics. These technologies provide a rapid, efficient and cost-effective way to move from DNA sequence DNA sequence Genetics The precise order of bases–A,T,G,C–in a segment of DNA, gene, chromosome, or an entire genome. See Base pair, Base sequence analysis, Chromosome, Gene, Genome. data to knowledge about the function of genes and the proteins that they encode. The company's technology is broadly applicable to all life science industries including pharmaceutical, diagnostic, agricultural biotechnology and animal health. Exelixis has partnerships with Bayer, Pharmacia, Bristol-Myers Squibb Bristol-Myers Squibb (NYSE: BMY), colloquially referred to as BMS, is a pharmaceutical corporation, formed by a 1989 merger between pharmaceutical companies Bristol-Myers Company, founded in 1887 by William McLaren Bristol and John Ripley Myers in Clinton, NY (both were and Dow AgroSciences Dow AgroSciences LLC is a wholly owned subsidiary of the Dow Chemical Company specializing in not only agricultural chemicals such as pesticides, but also seeds and biotechnology solutions. The company is based in Indianapolis, Indiana, in the United States. and is building its internal development program in the area of oncology. For more information, please visit the company's web site at www.exelixis.com. About Agilent Technologies Agilent Technologies Inc. (NYSE:A) is a diversified technology company with approximately 46,000 employees serving customers in more than 120 countries. Agilent is a global leader in designing and manufacturing test, measurement and monitoring instruments, systems and solutions, and semiconductor and optical components. In fiscal year 1999, Agilent had net revenue of more than $8.3 billion. The company serves markets that include communications, electronics, life sciences and healthcare. Information about Agilent Technologies can be found on the Web at www.agilent.com. |
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