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Agilent Technologies Launches AgBio Program with Introduction of Industry's First Microarray to Include Genetic Probes from Two Species.


Business Editors/Health/Medical Writers

BIOWIRE2K

PALO ALTO, Calif.--(BUSINESS WIRE)--May 15, 2003

New AgBiotech Product to Enable Agricultural and Biotech

Researchers to Develop Solutions to Biological Threats

to World Food Supply

Agilent Technologies Inc. (NYSE: A) today announced a new AgBiotech business program that incorporates elements of the gene expression, agricultural and food safety industries. Agilent plans to build upon its existing advanced microarray and microfluidics The science of building microminiaturized devices with chambers and tunnels for the containment and flow of fluids. With devices measured at the micrometer level and fluids measured in nanoliters and picoliters, microfluidics devices are widely used in ink jet printer heads and labs on a chip. The latter are used to analyze body fluids for medical purposes. See lab on a chip and nanofluidics. (bioanalyzer) technology platforms to develop a full range of AgBio-specific products and applications to address an estimated total available market of more than U.S. $500 million.(1)

The first product to be introduced as part of the new program is the Agilent Magnaporthe grisea Oligo Microarray Kit (G4137A), the industry's first commercial microarray to include genetic probes from two genomes on one microarray, specifically rice blast (Magnaporthe grisea) and rice. Rice blast, a filamentous filamentous /fil·a·men·tous/ (fil?ah-men´tus) composed of long, threadlike structures. fungus, is responsible for rice blast disease, which destroys enough rice to feed 60 million people each year. The unique design of this new microarray enables agricultural and biotech researchers to examine the molecular basis of plant diseases and develop environmentally sounds strategies to improve food quality. The new microarray was developed in collaboration with researchers at North Carolina State University.

"Rice blast and rice together constitute a model system for studying fungal infection in plants," said Ralph Dean, professor of Plant Pathology plant pathology: see diseases of plants. and director of the Fungal Genomics Laboratory at NCSU. "By having two genomes on one microarray, we will be able to study host-pathogen interactions between plants and fungi in a way that was never before possible."

"Agilent has long-standing relationships with many customers in the AgScience and food industries, providing chemical analysis chemical analysis, the study of the chemical composition and structure of substances. More broadly, it may be considered the corpus of all techniques whereby any exact chemical information is obtained. There are two branches in analytical chemistry: qualitative analysis and quantitative analysis. Qualitative analysis is the determination of those elements and compounds that are present in a sample of unknown material. equipment," said Mary Pat Knauss, manager of Agilent's AgBiotech program. "This new program addresses their biological needs in agricultural research, such as with this new microarray, and in the detection of pathogens, biological agents, or genetically modified organisms in food. As concerns about food quality and labeling worldwide increase, so is the demand for these advanced biological analysis techniques."

"The line between chemical and biological research has become increasingly blurred and this program bridges the two," said Chris van Ingen, senior vice president and general manager of Agilent's Life Science and Chemical Analysis group. "By leveraging our successful microarray and microfluidics technology platforms, we can quickly expand our product offerings and markets. This helps us to position LSCA LSCA - La Salle College Antipolo (Antipolo City, Rizal, Philippines)
LSCA - Large-Signal Circuit Analysis
LSCA - left subclavian artery
LSCA - Library Services & Construction Act of 1957
 for strong growth, while improving our operational efficiency."

Microarray and Microfluidics Technologies

Agilent began to establish relationships in the AgBiotech market several years ago, working closely with customers through its custom microarray program. Microarrays are used to measure the expression level of genes under varying conditions and are principally used in AgBiotech research to better understand plant genetics and gene function. Agilent's flexible ink-jet-based microarray manufacturing enables the development of highly sensitive microarrays with a lower upfront investment than competing technologies, enabling the company to address niche markets with microarrays for new genomes.

Microfluidics technologies have the potential to play an important role in food safety. The Agilent 2100 Bioanalyzer and associated LabChips can assess the quality and quantity of biological samples, including DNA, RNA, proteins, and cells. Potential AgBio applications for this technology include protein characterization, pathogen detection, and GMO screening, which could aid researchers who need to address new labeling requirements under regulatory development in Europe and around the world.

U.S. Availability

The Agilent Magnaporthe grisea Oligo Microarray Kit (G4137A) is now available. More information about Agilent's new AgBiotech program is available at www.agilent.com/chem/agbiotech.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global technology leader in communications, electronics, life sciences and chemical analysis. The company's 35,000 employees serve customers in more than 110 countries. Agilent had net revenue of $6 billion in fiscal year 2002. Information about Agilent is available on the Web at www.agilent.com.

Forward-Looking Statements

This news release contains forward-looking statements (including, without limitation, statements relating to Agilent's plans to use its advanced microarray and microfluidics (bioanalyzer) technologies to develop an entire range of AgBio-specific products and applications to address the estimated more than U.S. $500 million AgBiotech market) that involve risks and uncertainties that could cause results to differ materially from management's current expectations. These risks are detailed in the company's filings with the Securities and Exchange Commission, including its Annual Report on Form 10-K for the year ended Oct. 31, 2002; its Current Report on Form 8-K dated Jan. 24, 2003; and its Current Report on Form 8-K dated Feb. 10, 2003. The company assumes no obligation to update the information in this press release.

(1) Estimate is a composite figure developed by Agilent based on information from the following research reports:

-- "Health Care - Life Science Tools," Goldman Sachs, 2001.

-- "The Growing Food Testing Business: Highlighting Pathogens and

Pesticides," Business Communications Company, Inc., 1995.

-- "Analyst Report on Strategic Diagnostics," Deutsche Banc Alex

Brown, 1999.

-- "Laboratory Analytical Instrument Industry," Strategic

Direction, 2001.

Note to Editors: Press releases, photography and other information can be accessed on the Agilent Life Sciences and Chemical Analysis newsroom at www.agilent.com/about/newsroom/lsca.

Further technology, corporate citizenship and executive news is available on the Agilent news site at www.agilent.com/go/news.
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Publication:Business Wire
Geographic Code:1USA
Date:May 15, 2003
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