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Agilent Technologies Introduces Microarray Kit With Human Genome Screening Capabilities.


Business Editors & Medical/Health Writers

PALO ALTO Palo Alto, city, California
Palo Alto (păl`ō ăl`tō), city (1990 pop. 55,900), Santa Clara co., W Calif.; inc. 1894. Although primarily residential, Palo Alto has aerospace, electronics, and advanced research industries.
, Calif.--(BUSINESS WIRE)--Oct. 29, 2001

Second Kit in Agilent's Line of cDNA Microarray Kits for Human DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 

to Assist Researchers in Drug Discovery and Disease Research

Agilent Technologies This article needs sources or references that appear in reliable, third-party publications. Alone, primary sources and sources affiliated with the subject of this article are not sufficient for an accurate encyclopedia article.  Inc. (NYSE NYSE

See: New York Stock Exchange
:A) today introduced the second in its line of human cDNA microarray kits. The ready-to-use kit, with human genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes.  screening capabilities, delivers consistent genomic information to researchers racing to discover new drugs and diagnose diseases.

Based on Agilent's industrial-scale inkjet manufacturing of printed microarrays, these new cDNA microarrays contain more than 14,000 amplicons(1) representing cDNAs from Incyte's proprietary Human Foundation 1 and 2 clone sets. With the new Agilent Human 2 cDNA Microarray Kit (G4101A) and the previous version (G4100A), researchers can now study the expression of more than 25,000 human sequences with the convenience and consistency associated with a pre-packaged format.

"We've ramped up and made exciting breakthroughs in delivering cDNA microarrays that exhibit unparalleled consistency and quality," said Barney Saunders, vice president and general manager of Agilent's BioResearch bi·o·re·search  
n.
Research in the biological sciences.
 Solutions. "By using well-characterized content from Incyte Genomics, we're now able to provide researchers with genome-wide screening with our cDNA microarrays as well as targeted gene expression analysis using our custom in situ In place. When something is "in situ," it is in its original location.  microarrays designed with probes that map to Incyte clones or other sequences of interest."

"We're pleased with the speed by which Agilent is building their product line," said Roy A. Whitfield, chief executive officer of Incyte. "It's evident that their technology roots combined with their product-generation know-how have been brought to bear on taking our content to create cDNA microarrays and kits that should deliver a whole new level of consistency and quality not previously seen with 'in-lab/homebrew' microarrays and methods."

Agilent's cDNA microarrays are printed on standard 1" x 3" glass slides that can be imaged on numerous microarray scanners including Agilent's new 48-slide DNA Microarray scanner (G2565AA). In addition, the cDNA microarrays are based on a two-color assay format that enables simultaneous expression analysis of two samples on one microarray, reducing variability and increasing productivity. All Agilent cDNA microarray kits are delivered with four microarrays (two each printed per glass slide), hybridization hybridization /hy·brid·iza·tion/ (hi?brid-i-za´shun)
1. crossbreeding; the act or process of producing hybrids.

2. molecular hybridization

3.
 buffer, user protocol and a CD containing pertinent microarray layout information. For ease of use, an optional Agilent Fluorescent Direct Label Kit for cDNA synthesis and labeling is also available.

Availability

The Agilent Human 2 cDNA Microarray Kit is available now for commercial release in the United States, Canada, Japan and Europe. Further information is available by contacting a local Agilent sales representative, by e-mailing Agilent at dna_microarrays@agilent.com, or by visiting Agilent's Web site at www.agilent.com/chem/dna (enter code: BR3002).

Agilent in Gene Expression

Agilent offers a robust modular solution to improve customer productivity in gene expression. Key components include Agilent's flexible, high-quality industrial-scale inkjet printed DNA microarrays as well as custom microarray design services, RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
 and DNA LabChip(R) sample analysis kits, microarray reagents, DNA microarray scanners, and microarray analysis software featuring Rosetta Resolver(R) data analysis software.

About Agilent Technologies

Agilent Technologies Inc. (NYSE:A) is a global technology leader in communications, electronics and life sciences. The company's 43,000 employees serve customers in more than 120 countries. Agilent had net revenue of $9.4 billion in fiscal year 2000, as restated to reflect the sale of its healthcare business. Information about Agilent is available on the Web at www.agilent.com.

LabChip and the LabChip Logo are registered trademarks of Caliper caliper

Instrument that consists of two adjustable legs or jaws for measuring the dimensions of material parts. Spring calipers have an adjusting screw and nut; firm-joint calipers use friction at the joint to hold the legs unmoving.
 Technologies Corp. in the U.S. and other countries.

Rosetta Resolver is a U.S. trademark of Rosetta Inpharmatics.

(1) An amplicon is a small piece of DNA that has been amplified by PCR PCR polymerase chain reaction.

PCR
abbr.
polymerase chain reaction


Polymerase chain reaction (PCR) 
 (polymerase chain reaction polymerase chain reaction (pŏl`ĭmərās') (PCR), laboratory process in which a particular DNA segment from a mixture of DNA chains is rapidly replicated, producing a large, readily analyzed sample of a piece of DNA; the process is ).

NOTE TO EDITORS: Press releases, photography and other information can be accessed and downloaded from the Agilent Technologies Life Sciences and Chemical Analysis newsrooms at www.agilent.com/about/newsroom/lifesciences/ and www.agilent.com/about/newsroom/chemical/.
COPYRIGHT 2001 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2001, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Oct 29, 2001
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