Agennix announces the production of kilogram quantities of human lactoferrin.HOUSTON, Texas/TEESSIDE, England--(BUSINESS WIRE)--Nov. 27, 1995-- Agennix Inc., in collaboration with Zeneca BioMolecules This page aims to list articles on Wikipedia that describe particular biomolecules or types of biomolecules. This list is not necessarily complete or up to date - if you see an article that should be here but isn't (or one that shouldn't be here but is), please update the page , has successfully completed the fermentation and downstream processing Downstream processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of lactoferrin lactoferrin (lak´tōfer´in), n an iron-binding protein found in the specific granules of neutrophils where it apparently exerts an antimicrobial activity by withholding iron from ingested bacteria and fungi. -- an agent being developed by Agennix for use in the treatment of infectious diseases infectious diseases: see communicable diseases. . The companies have produced in excess of 10 kilograms of purified human lactoferrin from a single fermentation cycle, according to according to prep. 1. As stated or indicated by; on the authority of: according to historians. 2. In keeping with: according to instructions. 3. Denis Denis, king of Portugal: see Diniz. Headon, Ph.D., president and chief executive officer of Agennix. "This is an important milestone for Agennix, as we now have proven that large-scale production of human lactoferrin is commercially feasible," Headon said. "The purified human lactoferrin is being used for safety and toxicology studies and for various preclinical efficacy studies in infection." Zeneca BioMolecules, a part of Zeneca Specialties' newly formed LifeScience Molecules business, has provided expertise in recombinant production under a research and development agreement with Agennix. "Our skills in fermentation, downstream processing, protein purification Protein purification is a series of processes intended to isolate a single type of protein from a complex mixture. Protein purification is vital for the characterisation of the function, structure and interactions of the protein of interest. and process development have enabled the production of high purity material rapidly, which is key to the success of this project," said Stephen Taylor, Ph.D., general manager of Zeneca BioMolecules. "It is a good example of our partnership approach to biotechnology business development." Zeneca is a broadly based bioscience group comprising three international businesses, Pharmaceuticals, Agrochemicals and Specialties. Agennix is a biotechnology company engaged in the research and development of a new class of anti-infective drugs. The company's core underlying technology has been built on a human protein called lactoferrin, a broad spectrum, natural antimicrobial protein with anti-infective applications for the treatment of infectious diseases. CONTACT: Agennix Inc. Denis Headon, 713/796-1091 agennix@ix.netcom.com (e-mail) or Zeneca BioMolecules Stephen Taylor, Ph.D., +0 1642-523861 stephen.s.c.taylor@ukbla71.zeneca.com (e-mail) or Mentus Linda Seaton, 619/455-5500 lcs1@cerfnet.com (e-mail) |
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