Agencourt Bioscience Announces Publication Of DNA Sequence of Human Chromosome 10.Business Editors BEVERLY, Mass.--(BUSINESS WIRE)--May 27, 2004 Agencourt Bioscience in Collaboration with Wellcome Trust Sanger Institute Publishes Paper in Nature Agencourt Bioscience Corporation, a provider of genomic services and nucleic acid purification products to the life sciences industry, today announced the publication of the human chromosome 10 manuscript in the May 27th issue of Nature. Agencourt scientists contributed to the BAC BAC abbr. blood alcohol concentration based sequencing effort on the genome sequence of human chromosome 10, the finished sequence of which comprises a total of 131,666,441 base pairs represented by 1,357 annotated genes. Library construction and genome sequencing efforts began at Genome Therapeutics Corporation (now Oscient Pharmaceuticals) and were transferred to Agencourt Bioscience upon acquisition of the GenomeVision(TM) Services division. Agencourt continues to utilize this experience in the sequencing of additional genomes. In addition to Agencourt, the other major sequencing center was the Wellcome Trust Sanger Institute. "The completion of one of the human chromosomes is a major accomplishment for both our team and the other contributors. We are pleased this completed sequence with analysis of chromosome 10 is available to be used by researchers worldwide," said Douglas Smith, Ph.D., Principal Investigator and Director of Grants and Contracts at Agencourt. "Agencourt is now applying the experience we gained in sequencing portions of the human and rat genomes towards the sequencing of genomes of biomedically important organisms as part of the NHGRI NHGRI National Human Genome Research Institute Large-Scale Sequencing Research Network." About the National Human Genome Research Institute (NHGRI) NHGRI is one of 27 institutes and centers at the National Institutes of Heath, which is an agency of the Department of Health and Human Services Noun 1. Department of Health and Human Services - the United States federal department that administers all federal programs dealing with health and welfare; created in 1979 Health and Human Services, HHS . NHGRI's Division of Extramural extramural /ex·tra·mu·ral/ (-mur´il) situated or occurring outside the wall of an organ or structure. extramural situated or occurring outside the wall of an organ or structure. Research supports grants for research, and for training and career development at sites nationwide. About Agencourt Bioscience Corporation Agencourt Bioscience Corporation is a provider of genomic services and nucleic acid purification products that help biotech and pharmaceutical companies improve the effectiveness and efficiency of their drug development pipelines. Agencourt's Discovery Solutions(TM) suite of genomic and functional genomic services includes high-throughput sequencing, SAGE(TM) sequencing, library construction and SNP SNP Scottish National Party Noun 1. SNP - (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily discovery. The company's purification products and services are based on the proven and patented Solid Phase Reversible Immobilization Immobilization Definition Immobilization refers to the process of holding a joint or bone in place with a splint, cast, or brace. This is done to prevent an injured area from moving while it heals. (SPRI SPRI Scott Polar Research Institute (University of Cambridge) SPRI Single Ply Roofing Institute SPRI Schering-Plough Research Institute (Corporate division) (TM)) technology, which has been adopted by several of the largest genome research facilities, resulting in more base pairs contributed to GenBank than any other nucleic acid purification technology and used to sequence over one-third of the human genome. In 2003, Agencourt was awarded one of five large-scale sequencing grants from NHGRI to sequence genomes of high biomedical bi·o·med·i·cal adj. 1. Of or relating to biomedicine. 2. Of, relating to, or involving biological, medical, and physical sciences. importance. The company has also been confirmed to be operating in compliance with the requirements of the Good Laboratory Practices (GLP See gateway location protocol. ) as a contract analytical laboratory. Agencourt is located in Beverly, Massachusetts and is available on the Web at www.agencourt.com. |
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