Agencourt Announces Winner of Pan-Mass Genomic Services Grant to Help Fund Cancer Research.Business Editors/Health/Medical Writers
BEVERLY, Mass.--(BUSINESS WIRE)--Feb. 9, 2004
Dana-Farber Researcher Will Use Agencourt's Sequencing Services to
Identify Gene Responsible for Rare Tumor of the Adrenal Gland adrenal gland (ədrēn`əl) or suprarenal gland (sprərēn`əl), endocrine gland (see endocrine system) about 2 in. (5.
Agencourt Bioscience Corporation, a provider of genomic services and nucleic acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis. purification products to the life sciences industry, has awarded Patricia Dahia, Ph.D., Instructor of Medicine at the Dana-Farber Cancer Institute, the $10,000 Agencourt Pan-Mass Genomic Services Grant. The grant is being presented as part of Agencourt's sponsorship of the 2003 Pan-Massachusetts Challenge, an annual bicycle race across the state that raises funds for the Jimmy Fund, a Dana-Farber Cancer Institute charity.
Dr. Dahia was selected for her proposal, "A Novel Familial Pheochromocytoma Pheochromocytoma Definition
Pheochromocytoma is a tumor of special cells (called chromaffin cells), most often found in the middle of the adrenal gland. Susceptibility Locus: towards identification of the target gene." The goal of this study is to identify the gene(s) responsible for novel familial pheochromocytoma syndrome (FP). Pheochromocytoma is a rare tumor of the adrenal gland that can increase production of adrenaline and can cause life-threatening elevation in blood pressure. Identification of the FP gene will provide tools for early diagnosis of affected individuals and, as a result, guide therapeutic decisions. Agencourt's high-throughput sequencing capabilities will play a fundamental role in the identification of the susceptibility gene in this disorder.
"Agencourt is very proud to award this year's Genomic Services Grant to Dr. Dahia," said Krista Steger, Marketing Manager at Agencourt. "Although pheochromocytomas are rare, identifying the disease is critical because patients often exhibit few to no symptoms. It is our hope that Agencourt's sequencing services will greatly aid Dr. Dahia in her effort to accelerate the diagnosis, treatment and prevention of FP."
Sequencing, the determination of the order of nucleotides (basic subunits of DNA DNA: see nucleic acid.
or deoxyribonucleic acid
One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. ), aids researchers in identifying genes involved in various biological processes, including cancer. This type of information allows researchers to better understand the development of cancer and pinpoint potential means of therapy and cancer diagnosis.
"We are very pleased that Agencourt has chosen to support Dr. Dahia's research through its services grant," said Kornelia Polyak, M.D., Ph.D., a Dana-Farber physician-scientist and member of the grant selection committee. "This grant will help us further our understanding of cancer."
The Agencourt Pan-Mass Genomic Services Grant was awarded to a researcher at the Dana-Farber Cancer Institute performing oncology-related research with the potential to significantly increase the understanding of the cellular processes leading to cancer, or provide insights into the diagnosis or treatment of cancer. A scientific committee comprised of individuals from the Dana-Farber Cancer Institute and Agencourt Bioscience reviewed the applications.
About Agencourt Bioscience Corporation
Agencourt Bioscience Corporation is a provider of genomic services and nucleic acid purification products that help biotech and pharmaceutical companies improve the effectiveness and efficiency of their drug development pipelines. Agencourt's Discovery Solutions(TM) suite of genomic and functional genomic services includes high-throughput sequencing, SAGE(TM) sequencing, library construction and SNP SNP Scottish National Party
Noun 1. SNP - (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily discovery. The company's purification products and services are based on the proven and patented Solid Phase Reversible Immobilization Immobilization Definition
Immobilization refers to the process of holding a joint or bone in place with a splint, cast, or brace. This is done to prevent an injured area from moving while it heals. (SPRI SPRI Scott Polar Research Institute (University of Cambridge)
SPRI Single Ply Roofing Institute
SPRI Schering-Plough Research Institute (Corporate division) ) technology, which has been adopted by several of the largest genome research Genome Research is the title of a peer-reviewed scientific journal published by Cold Spring Harbor Laboratory Press. The focus of the journal is on genome-wide studies in any organism, including single gene studies that are placed in a genomic context. facilities, resulting in more base pairs contributed to GenBank than any other nucleic acid purification technology and used to sequence over one-third of the human genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes. . Agencourt has been confirmed to be operating in compliance with the requirements of the Good Laboratory Practices (GLP See gateway location protocol. ) as a contract analytical laboratory. Several of Agencourt's founders worked at the Whitehead Institute Founded in 1982, the Whitehead Institute for Biomedical Research is a non-profit research and teaching institution located in Cambridge, Massachusetts. The Whitehead Institute was founded as a fiscally independent entity from Massachusetts Institute of Technology, and its members Center for Genome Research, and have significant experience in combining the chemistries and instrumentation for high-throughput genomics. Agencourt is located in Beverly, Massachusetts and is available on the Web at www.agencourt.com.