Affymetrix Automated Microarray Processing Platform Analyzes up to 96 Samples at a Time.GeneChip([R]) HT Array Plate System Increases Productivity by Decreasing Processing Time, Improving Data Consistency Data consistency summarizes the validity, accuracy, usability and integrity of related data between applications and across the IT enterprise. This ensures that each user observes a consistent view of the data, including visible changes made by the user's own transactions and and Reducing Overall Costs SANTA CLARA Santa Clara, city, Cuba Santa Clara (sän`tä klä`rä), city (1994 est. pop. 217,000), capital of Villa Clara prov., central Cuba. , Calif. -- Affymetrix Inc. (NASDAQ NASDAQ in full National Association of Securities Dealers Automated Quotations U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on : AFFX) today announced the commercial launch of its GeneChip([R]) HT Array Plate System, a full microarray See micro array. microarray - A technique for performing many DNA experiments in parallel. Nothing to do with computers. processing platform that analyzes up to 96 samples at a time. The HT Array Plates offer the same comprehensive, validated content as the traditional cartridges in a format designed for larger-scale studies. The complete system increases productivity for large-scale gene expression studies by decreasing processing time, improving data consistency and reducing overall costs. Researchers at large pharmaceutical companies and clinical research laboratories can now increase the scope and scale of their gene expression microarray projects without additional manpower. The automated system provides consistent microarray data for every experimental sample run, which drastically reduces the need to reanalyze samples. The HT Array Plate System also helps ensure reproducible data for large-scale studies that are conducted in multiple laboratories. Compared to manual methods, the complete HT Array Plate System reduces the overall required labor time by at least 40 percent. Scientists at Avalon Pharmaceuticals have processed thousands of samples on the system and are using the data to identify and develop new compounds for oncology oncology /on·col·o·gy/ (ong-kol´ah-je) the sum of knowledge regarding tumors; the study of tumors. on·col·o·gy n. therapeutics therapeutics Treatment and care to combat disease or alleviate pain or injury. Its tools include drugs, surgery, radiation therapy, mechanical devices, diet, and psychiatry. . The Affymetrix system enables the team to analyze compound effects across thousands of genes simultaneously, and compare the activity of compounds to a large transcription database derived from cellular treatments. "The Affymetrix HT Array Plate System enables high-throughput gene expression studies in a highly reliable, reproducible and cost-effective manner," said Dan Soppet, Ph.D., director of lead development at Avalon Pharmaceuticals. "When compared to our previous two color glass slide arrays, the automated 96-well format has more than doubled our throughput, while reducing process failures by 10-fold to a level of 1 to 2 percent. These features allow us to confidently schedule research programs and rapidly produce very high-quality results for both internal discovery and corporate partnerships." Complete Microarray Processing System The Affymetrix HT Array Plate System is built on the same GeneChip([R]) technology that has been the industry standard in microarray research for the past decade. The system includes flexible instrumentation, proven GeneChip([R]) microarrays, optimized assays and reagents as well as open software architecture. The integral components include: * GeneChip([R])HT Array Plates--provide comprehensive coverage of the transcribed human, mouse and rat genomes in a convenient configuration that enables researchers to interrogate (1) To search, sum or count records in a file. See query. (2) To test the condition or status of a terminal or computer system. either 24 or 96 distinct samples at one time * GeneChip([R]) HT One-Cycle Target Labeling and Control Reagents--offer optimized target preparation kit for large-scale gene expression studies * GeneChip([R])Array Station for automated target preparation and microarray processing--allows one person to prepare the same number of targets that four people could accomplish manually * GeneChip([R]) HT Array Plate Scanner--delivers the industry-leading image quality and turnaround time (1) In batch processing, the time it takes to receive finished reports after submission of documents or files for processing. In an online environment, turnaround time is the same as response time. of less than three minutes "Three Minutes" is the 46th episode of Lost. It is the twenty-second episode of the second season. The episode was directed by Stephen Williams, and written by Edward Kitsis and Adam Horowitz. It first aired on May 17, 2006 on ABC. per array * GeneChip([R]) HT Software Suite--features latest version of GeneChip([R]) Operating Software (GCOS (General Comprehensive OS) An operating system from Bull that, originally used in its minis and mainframes, has migrated to its Intel-based servers. GCOS was originally developed by GE in the early 1970s as GECOS (GE Comprehensive OS), then changed to General ), HT Image Reader and HT Data Transfer Tool "Affymetrix has set the standard in the industry for whole-genome 3' expression arrays with thousands of peer-reviewed publications citing the technology," said Chip Leveille, vice president of the pharmaceutical business unit at Affymetrix. "The GeneChip HT Array Plate System makes this same comprehensive and well-proven content available in a format designed to better enable larger-scale studies, while reducing overall study costs and processing variability." For more information on the Affymetrix GeneChip HT Array Plate System, please visit: www.affymetrix.com/genechip/htap.affx. About Affymetrix Affymetrix GeneChip([R])microarray technology is the industry-standard tool for analyzing complex genetic information. After inventing microarray technology in the late 1980s, Affymetrix scientists have been dedicated to developing innovative products that provide researchers with a more complete view of the genome. These products continue to accelerate genetic research and enable scientists to develop diagnostics and tailor treatments for individual patients by identifying and measuring the genetic information associated with complex diseases. Today, Affymetrix technology is used by the world's top pharmaceutical, diagnostic and biotechnology companies Top 100 Biotechnology Companies The following is a list of the top 100 biotechnology companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies. , as well as leading academic, government and not-for-profit research institutes. More than 1,500 systems have been shipped around the world and more than 8,500 peer-reviewed papers have been published using the technology. Affymetrix is headquartered in Santa Clara, Calif., and has manufacturing facilities in Sacramento, Calif., and Singapore. The company has about 1,100 employees worldwide and maintains sales and distribution operations across Europe and Asia. For more information about Affymetrix, please visit the company's website at www.affymetrix.com. Forward-looking Statements forward-looking statement A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections. All statements in this press release that are not historical are "forward-looking statements" within the meaning of Section 21E of the Securities Exchange Act as amended, including statements regarding Affymetrix' "expectations," "beliefs," "hopes," "intentions," "strategies" or the like. Such statements are subject to risks and uncertainties that could cause actual results to differ materially for Affymetrix from those projected, including, but not limited to: risks and uncertainties associated with the success of the GeneChip([R]) HT Array Plate System discussed in this press release; risks of the company's ability to achieve and sustain higher levels of revenue, higher gross margins and reduced operating expenses Operating expenses The amount paid for asset maintenance or the cost of doing business, excluding depreciation. Earnings are distributed after operating expenses are deducted. ; uncertainties relating to relating to relate prep → concernant relating to relate prep → bezüglich +gen, mit Bezug auf +acc technological approaches, manufacturing and product development; personnel retention; uncertainties related to cost and pricing of Affymetrix products; dependence on collaborative partners; uncertainties relating to sole-source suppliers; uncertainties relating to FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. and other regulatory approvals; competition; risks relating to intellectual property of others and the uncertainties of patent protection and litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute. When a person begins a civil lawsuit, the person enters into a process called litigation. . These and other risk factors are discussed in Affymetrix' Form 10-K Form 10-K A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information. Form 10-K See 10-K. for the year ended December 31, 2006, and other SEC reports, including its Quarterly Reports on Form 10-Q Form 10-Q See 10-Q. for subsequent quarterly periods. Affymetrix expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Affymetrix' expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based. NOTE: Affymetrix, the Affymetrix logo and GeneChip([R]) are registered trademarks owned or used by Affymetrix Inc. |
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