Advanced Cell Technology Announces Completion of Its First GMP Laboratory.ALAMEDA, Calif. -- Advanced Cell Technology, Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :ACTC ACTC Apple Certified Technical Coordinator ACTC Almaden Cycle Touring Club ACTC Associated Colleges of the Twin Cities ACTC All Ceylon Tamil Congress (Sri Lanka) ACTC Association Canadienne de Télévision par Câble ) announced today that it is in the final phase of validating its first Good Manufacturing Practices ("GMP GMP (guanosine monophosphate): see guanine. ") laboratory in its facility in Worcester, Massachusetts. The Company expects to complete the validation of its new 800 square foot GMP laboratory in April and to commence scientific work under GMP conditions in early May. The initial focus of the Company's scientific work in the new laboratory will be the derivation and differentiation of human embryonic stem (ES) cells under GMP conditions to be used in pre-clinical testing and, then later, in Phase I human clinical trials. The Company expects to initially derive human ES cells and then differentiate those ES cells into retinal pigment epithelium The retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells. (RPE RPE Retinal Pigment Epithelium RPE Rating of Perceived Exertion (exercise) RPE Respiratory Protective Equipment RPE Regular Pulse Excitation RPE Registered Professional Engineer RPE Rapid Palatal Expansion ) cells and hemangioblast cells to support its therapeutic programs. These programs specifically target age-related diseases of the eye such as macular degeneration macular degeneration, eye disorder causing loss of central vision. The affected area, the macula, lies at the back of the retina and is the part that produces the sharpest vision. and cardiovascular diseases such as coronary artery disease coronary artery disease, condition that results when the coronary arteries are narrowed or occluded, most commonly by atherosclerotic deposits of fibrous and fatty tissue. and congestive heart failure congestive heart failure, inability of the heart to expel sufficient blood to keep pace with the metabolic demands of the body. In the healthy individual the heart can tolerate large increases of workload for a considerable length of time. . The Company's scientific team has previously derived and differentiated both retinal pigment epithelium (RPE) and hemangioblast cell types, and is now looking forward to deriving these cells under GMP conditions for additional preclinical testing and, ultimately, human clinical trials. William Caldwell, CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Advanced Cell Technology said, "The completion of our first GMP laboratory represents a significant development milestone for the Company. By deriving our target cell types under GMP we can now accelerate our therapeutic programs to complete pre-clinical animal testing and begin taking aim at Phase I human clinical trials." "Completion of this GMP facility in Worcester is the result of a team effort," commented Dr. Robert Lanza, VP of Medical and Scientific Development. "We look forward to using this facility to drive our new embryonic stem cell Embryonic stem cells (ES cells) are stem cells derived from the inner cell mass of an early stage embryo known as a blastocyst. Human embryos reach the blastocyst stage 4-5 days post fertilization, at which time they consist of 50-150 cells. ES cells are pluripotent. therapies to the clinic." About Advanced Cell Technology, Inc. Advanced Cell Technology, Inc. is a biotechnology company applying embryonic stem cell technology in the emerging field of regenerative medicine. The company operates facilities in Alameda, California and Worcester, Massachusetts. For more information about the company, please visit http://www.advancedcell.com. Forward-Looking Statements Statements in this news release regarding future financial and operating results, future growth in research and development programs, potential applications of our technology, opportunities for the company and any other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995. Any statements that are not statements of historical fact (including statements containing the words "will," "believes," "plans," "anticipates," "expects," "estimates," and similar expressions) should also be considered to be forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward-looking statements, including: limited operating history, need for future capital, risks inherent in the development and commercialization of potential products, protection of our intellectual property, and economic conditions generally. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in the company's periodic reports, including the report on Form 10-KSB for the fiscal year ended December 31, 2005. Forward-looking statements are based on the beliefs, opinions, and expectations of the company's management at the time they are made, and the company does not assume any obligation to update its forward-looking statements if those beliefs, opinions, expectations, or other circumstances should change. |
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