Adrenal toxicology.

9781420061291

Adrenal toxicology.

Ed. by Philip W. Harvey et al.

Informa Healthcare

2009

310 pages

$249.95

Hardcover

Target organ toxicology series; v.26

RC659

This volume has been conceived as a complement to and update of The Adrenal in Toxicology: Target Organ and Modulator of Toxicity (1996). Avoiding overlap with that text, it reviews major developments in the field over the last decade, focusing on the adrenal as a target organ in the main mammalian species used in pharmaceutical and chemical regulatory toxicology and on environmental sentinel species, as well as on advances in identifying molecular mechanisms of action. More discussion is included on the cortex rather than the medulla, reflecting the wider and more complex role of the former in physiological processes, although the pathology of the medulla is examined in the rodent and the human.

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