Acusphere to Present at the Lazard Capital Markets 3rd Annual Life Sciences Conference.

WATERTOWN, Mass. -- Acusphere, Inc. (NASDAQ: ACUS) announced today that it is scheduled to present at the Lazard Capital Markets 3rd Annual Life Sciences Conference on Tuesday, November 28, 2006 at 9:00 a.m. local time. Presenting for the company will be Sherri C. Oberg, President and Chief Executive Officer. The conference is being held at The New York Palace Hotel in New York City which is located at 455 Madison Avenue.

A webcast of the Company's presentation will be available both live and on a recorded basis via a link provided at the company's website www.acusphere.com on the Investor Relations page.

About Acusphere, Inc.

Acusphere (NASDAQ: ACUS) is a specialty pharmaceutical company that develops new drugs and improved formulations of existing drugs using its proprietary microsphere technology. Acusphere's three initial product candidates are designed to address large unmet clinical needs within cardiology, oncology and asthma. These product candidates were created using proprietary technology that enables Acusphere to control the porosity and size of nanoparticles and microspheres in a versatile manner that allows the microspheres to be customized to address the delivery needs of a variety of drugs. For more information about Acusphere visit the Company's web site at www.acusphere.com. "Acusphere" is a trademark of Acusphere, Inc.