Acusphere to Present at the Cowen and Company 27th Annual Health Care Conference.

WATERTOWN, Mass. -- Acusphere, Inc. (NASDAQ: ACUS) announced today that it is scheduled to present at the Cowen and Company 27th Annual Health Care conference on Tuesday, March 13, 2007 at 8:45 a.m. Eastern Time. The conference is being held at The Boston Marriott Copley Place in Boston, MA. Presenting for the Company will be Sherri C. Oberg, President and Chief Executive Officer.

A webcast of the Company's presentation will be available both live and on a recorded basis via a link provided at the company's website www.acusphere.com on the Investor Relations page. The recording will be available through March 27, 2007.

About Acusphere, Inc.

Acusphere (NASDAQ: ACUS) is a specialty pharmaceutical company that develops new drugs and improved formulations of existing drugs using its proprietary microsphere technology. Acusphere's three initial product candidates are designed to address large unmet clinical needs within cardiology, oncology and asthma. These product candidates were created using proprietary technology that enables Acusphere to control the porosity and size of nanoparticles and microspheres in a versatile manner that allows them to be customized to address the delivery needs of a variety of drugs. Acusphere's lead product candidate, Imagify[TM] (perflubutane polymer microspheres) injectable suspension, is a cardiovascular drug in Phase 3 clinical development. Imagify is designed to enable ultrasound to compete more effectively with nuclear stress testing, the leading procedure for detecting coronary artery disease. It is estimated that over 10 million procedures are done each year in the U.S. to detect coronary artery disease, the leading cause of death in the United States. For more information about Acusphere visit the Company's web site at www.acusphere.com. "Acusphere" and "Imagify" are trademarks of Acusphere, Inc.